Clinical and radiographic outcomes of dynamic navigation-assisted and freehand zygomatic implant surgery: a retrospective study with an average follow-up of 5 years.

Little evidence was available regarding the long-term clinical outcomes of zygomatic implants placed with dynamic navigation assistance compared to freehand zygomatic implants placement. The study aimed to evaluate the clinical and radiographic outcomes of dynamic navigation-assisted and freehand zygomatic implant placement over an average observation period of 5 years. Zygomatic implants were placed in patients with dynamic navigation assistance or by freehand.

Effect of Auxiliary Occlussal Devices on the Occlusal Accuracy of Multiple Implant-Supported Restorations Fabricated Using Digital Workflow: A Randomized Control Trial.

Objective: This study aimed to evaluate the effectiveness of auxiliary occlusal devices (AODs) in improving occlusal accuracy and reducing clinical adjustments in a fully digital workflow for multiple (3 or more) implant-supported single crowns.

Materials And Methods: Twenty-nine patients with a total of 106 implant-supported single crowns were enrolled. Participants were randomly assigned to either the test group (with AODs) or the control group (without AODs).

Three-dimensional analysis of implant-supported fixed prosthesis in the edentulous maxilla: a retrospective study.

Background: The maxillary incisal edge position is considered the starting point for full-mouth reconstructions. This retrospective study employed three-dimensional virtually planned patient data to evaluate the positional relationship between the upper incisor and underlying alveolar bone in implant-supported fixed prostheses of the edentulous maxilla and the associated influencing factors.

Methods: Three-dimensional virtual models were constructed for 22 edentulous patients rehabilitated with implant-supported fixed prostheses using cone-beam computed tomography, facial and denture scan data.

PIK3R3 regulates differentiation and senescence of periodontal ligament stem cells and mitigates age-related alveolar bone loss by modulating FOXO1 expression.

Introduction: Periodontal diseases are prevalent among middle-aged and elderly individuals. There's still no satisfactory solution for tooth loss caused by periodontal diseases. Human periodontal ligament stem cells (hPDLSCs) is a distinctive subgroup of mesenchymal stem cells, which play a crucial role in periodontal supportive tissues, but their application value hasn't been fully explored yet.

An innovative evaluation method for clinical comparative analysis of occlusal contact regions obtained via intraoral scanning and conventional impression procedures: a clinical trial.

Objectives: To compare the occlusal contact regions (OCRs) obtained through an intraoral scanning system and conventional impression procedures via an innovative evaluation method.

Materials And Methods: Fifteen participants with complete dentitions and stable centric occlusion were included. Three groups were created based on the technique used to obtain the OCRs of quadrant posterior teeth at the maximal intercuspal position: 100 μm articulating paper (Control), an intraoral scanner (Test 1, T1) and conventional impression procedure (Test 2, T2).

Multifunctional aggregation network of cell nuclei segmentation aiming histopathological diagnosis assistance: A new MA-Net construction.

Automated diagnostic systems can enhance the accuracy and efficiency of pathological diagnoses, nuclear segmentation plays a crucial role in computer-aided diagnosis systems for histopathology. However, achieving accurate nuclear segmentation is challenging due to the complex background tissue structures and significant variations in cell morphology and size in pathological images. In this study, we have proposed a U-Net based deep learning model, called MA-Net(Multifunctional Aggregation Network), to accurately segmenting nuclei from H&E stained images.

Impact of vertical alveoloplasty on changes in keratinized mucosa width following full-arch immediate implant placement and rehabilitations: A prospective case series.

Purpose: This prospective case series aimed to investigate the effect of vertical alveoloplasty on the changes in keratinized mucosa width (KMW) following full-arch immediate implant placement and rehabilitation.

Materials And Methods: A total of 17 potential edentulous patients were enrolled and received implant placement and full-arch implant-supported immediate rehabilitations. The main outcome was to analyze the effect of vertical alveoloplasty on the changes in KMW.

Digital registration versus cone-beam computed tomography for evaluating implant position: a prospective cohort study.

Background: Postoperative cone-beam computed tomography (CBCT) examination is considered a reliable method for clinicians to assess the positions of implants. Nevertheless, CBCT has drawbacks involving radiation exposure and high costs. Moreover, the image quality can be affected by artifacts.

Quantitative analysis of the color in six CAD-CAM dental materials of varied thickness and surface roughness: An in vitro study.

Statement Of Problem: Computer-aided design and computer-aided manufacturing (CAD-CAM) monochromatic restorative materials are gaining popularity because of their convenience and efficiency. However, studies that quantitatively analyzed color change associated with thickness and surface roughness are sparse.

Purpose: The purpose of this in vitro study was to quantitatively evaluate the color of 6 CAD-CAM monochromatic materials of different thickness and surface roughness using the CIELab color system.

Effects of thickness and polishing treatment on the translucency and opalescence of six dental CAD-CAM monolithic restorative materials: an in vitro study.

Background: Computer-aided design and computer-aided manufacturing (CAD-CAM) materials for prosthetic is gaining popularity in dentistry. However, limited information exists regarding the impact of thickness and roughening treatment on the optical properties of contemporary CAD-CAM restorative materials. This study aimed to quantitatively evaluate the translucency and opalescence of six dental CAD-CAM materials in response to different thicknesses and roughening treatments.

Clinical evaluation and quantitative occlusal change analysis of posterior implant-supported all-ceramic crowns: A 3-year randomized controlled clinical trial.

Objectives: To compare the survival and complication rates of posterior screw-retained monolithic lithium disilicate (LS )/veneered zirconia (ZrO ) single implant crowns (SICs), as well as analyze the occlusal changes observed during a 3-year follow-up period.

Materials And Methods: Thirty-three patients were included and randomly divided into two groups. The test group consisted of 17 patients who received monolithic-LS -SIC, while the control group consisted of 16 patients who received veneered-ZrO -SIC.

Lateral sinus floor elevation in patients with sinus floor defects: A retrospective study with a 1- to 9-year follow-up.

Objectives: We aimed to retrospectively evaluate the long-term clinical outcomes of lateral sinus floor elevation (LSFE) in patients with sinus floor defects.

Materials And Methods: Between 2008 and 2020, patients with sinus floor defects were recruited after confirmation on preoperative cone-beam computed tomography (CBCT). The split-thickness flap technique with a palatal crestal incision was used to manage tissue adhesion in the bone defects area.

Topical Application of Butyl Flufenamate Ointment Promotes Cranial Defect Healing in Mice by Inducing BMP2 Secretion in Skin Mesenchymal Stem Cells.

Bone defects and fractures heal slowly compared with injuries to other tissues, creating a heavy burden for patients, their families, and society. Alongside conventional treatment methods for fractures and bone defects, adjuvant therapies play an important but underappreciated role. In a previous study, we found that systemic administration of flufenamic acid promoted osteogenesis in vivo, but its side effects limited the application of our findings.

Quantitative analysis of color accuracy and bias in 4 dental CAD-CAM monolithic restorative materials with different thicknesses: An in vitro study.

Statement Of Problem: Computer-aided design and computer-aided manufacturing (CAD-CAM) monolithic restorative materials have become a popular option because of advantages such as convenience and efficiency. However, studies that quantitatively analyzed their color accuracy and bias are lacking.

Purpose: The purpose of this in vitro study was to evaluate the color accuracy and bias of 4 CAD-CAM monolithic restorative materials with different thicknesses by using the CIELab color space.

Effects of printing layer thickness on mechanical properties of 3D-printed custom trays.

Statement Of Problem: The layer thickness serves as a straightforward and controllable parameter to alter the mechanical properties of 3D-printed custom trays. However, how the printing layer thickness affects the mechanical properties of the trays is not fully understood.

Purpose: The purpose of this in vitro study was to investigate the effects and their underlying mechanisms and to optimize the mechanical properties through modulation of the printing layer thickness.

Clinical and radiographic outcomes of reentry lateral sinus floor elevation after a complete membrane perforation.

Background: Although small perforation of the maxillary sinus schneiderian membrane is a well-documented complication during lateral sinus floor elevation (LSFE), complete perforations larger than 10 mm often result in discontinuation of surgery. Reports on reentry LSFE and its long-term outcomes are sparse.

Purpose: To evaluate the long-term outcomes of reentry LSFE following complete membrane perforation to elucidate the technical details of the reentry procedure.

Evaluation of intraoral digital impressions for obtaining gingival contour in the esthetic zone: accuracy outcomes.

Objectives: To assess the accuracy of intraoral digital impressions for gingival contour captured in the esthetic zone in vivo.

Material And Methods: Five participants with full upper dentition were recruited. For each participant, three scans were taken using two intraoral scanning (IOS) systems (3Shape TRIOS Color, TRC; CEREC Omnicam, OC) respectively; three conventional impressions (CIs) were taken using vinyl polysiloxane materials.

Quantitative clinical adjustment analysis of posterior single implant crown in a chairside digital workflow: A randomized controlled trial.

Objectives: To compare the three-dimensional changes in quantity and morphology following clinical adjustment of a posterior single implant crown between chairside digital workflow (test) and hybrid digital workflow (control).

Materials And Methods: A total of 33 participants were included for single-tooth replacement with screw-retained crowns in posterior sites of either the maxillary or mandible. A total of 17 participants were carried to a chairside digital workflow, receiving monolithic lithium disilicate (LS2)-crowns (test), while the remaining 16 participants were fitted with CAD/CAM-fabricated zirconia superstructures and hand-layered ceramic veneering crowns (control).

Labial soft tissue contour dynamics following immediate implants and immediate provisionalization of single maxillary incisors: A 1-year prospective study.

Background: Soft tissue dynamics in the esthetic zone are gaining increasing attention in recent years. Emerging intraoral scanning technology allows easier capture of soft tissue contours.

Purpose: To quantitatively assess the time-dependent contour alterations of labial soft tissue following single immediate implants and immediate provisionalization (IIPP) in maxillary incisors via intraoral scanning.