Computational Fluid Dynamics Simulations to Personalize Nasal Irrigations.

: Proper nasal irrigation techniques are essential for treating nasal and sinus conditions, influencing drug delivery efficiency and patient comfort. This study evaluates how different head positions-upright, right-tilted, and left-tilted-affect the distribution of saline solution in the nasal cavity and maxillary sinus using computational fluid dynamics (CFD). : CFD simulations were conducted on a CT-based model of a healthy adult.

Evaluation of Artificial Intelligence Chatbots for Facial Injection Planning: Comparative Performance and Safety Limitations.

Background: To evaluate the performance of artificial intelligence (AI)-powered chatbots in generating treatment plans for facial aesthetic injections, focusing on their accuracy, safety, and clinical applicability.

Methods: A comparative observational study was conducted in an otolaryngology tertiary care department according to STROBE guidelines. Patients seeking facial injections were recruited from July to October 2024.

Intracochlear Drug Delivery Using a Catheter and Dexamethasone-Eluting Electrode Preserves Residual Hearing Post-Cochlear Implantation.

Objectives: This study aims to assess the feasibility and safety of a cochlear catheter (cannula) for inner ear drug delivery during cochlear implantation. We evaluated the otoprotective effect of L-N-acetylcysteine (L-NAC) administered via a cannula in combination with a dexamethasone-eluting cochlear implant (CI).

Study Design: An animal model study.

Can numerical modeling help us understanding hydrops in Menière's disease? A PRISMA scoping review.

BackgroundThe pathophysiology of Meniere's disease (MD) is complex and intertwined with endolymphatic hydrops. Available experimental models have limitations.ObjectiveThis study aimed to analyze the impact of endolymphatic hydrops on cochleovestibular hydrodynamics through numerical simulations.

Vestibular Aqueduct and Temporal Bone Radioanatomy in Patients With and Without Meniere Disease: A Retrospective Cross-Sectional Analysis With Implications for Endolymphatic Sac Surgery.

Objectives: The vestibular aqueduct (VA) exhibits significant anatomical variability. These variations and their spatial relationships with neighboring structures may pose technical challenges during endolymphatic sac surgery. We aimed to characterize the anatomical features of the VA and its relationship with surrounding structures in patients with severe Meniere disease compared to controls using high-resolution computed tomography (CT).

Endolymphatic Duct Blockage and Anatomical Variations Management.

Endolymphatic duct blockage technique should be dictated by a precise anatomical understanding and surgical adaptation. This article focuses on the surgical approaches and anatomical variations of the endolymphatic sac during the transmastoid route, which varies with the size of the duct within the petrous bone and its accessibility. Laryngoscope, 135:2097-2099, 2025.

Sound-induced drug distribution in the cochlea, how close are we? A PRISMA scoping review.

Objective: To evaluate the efficacy of sound stimulation for enhancing drug distribution in the cochlea's perilymph, crucial for treating one of the most inaccessible organs and a major disability factor worldwide.

Design: A systematic scoping review following PRISMA guidelines was conducted, analysing studies on cochlear fluid dynamics influenced by sound stimulation. Data were collected from PubMed and Google Scholar using both MeSH and non-MeSH terms, with exclusions for unrelated topics.

Prospective Evaluation of Aesthetic and Functional Outcomes following Video-Assisted Rhino-Septoplasty.

Background: Conservative techniques have been developed in the field of rhinoplasty, focusing on limited tissue resection while emphasizing the reshaping of nasal structural elements.

Objectives: We aimed to prospectively evaluate aesthetic and functional outcomes following Video-Assisted Rhino-Septoplasty (VARS) using validated tools.

Methods: Patients' self-reported outcomes were assessed before and 6 months after surgery.

Advancing the Era of Liquid Rhinoplasty: A Methodological Approach to Injection Protocols.

Background: Liquid rhinoplasty, a non-surgical procedure using hyaluronic acid (HA) to reshape and refine the nose, has gained in popularity as an alternative to traditional surgical rhinoplasty although its results are not definitive. However, the lack of standardized injection protocols has raised concerns about treatment consistency and patient safety.

Objectives: In this article, the authors propose a systematic protocol for the most common indications of liquid rhinoplasty.

Reply to: "Invited Discussion on: Video Assisted Septo-Rhinoplasty, the Future of Endonasal Rhinoplasty-a Technical Note".

We respond to Gryskiewic and Alameddine's commentary on our recent study regarding endoscopic use in rhinoplasty. Highlighting the context-dependent nature of technique superiority, we discuss the alternative approach of Video Assisted Rhinoseptoplasty (VARS) in mitigating visible scarring concerns. Additionally, we emphasize the benefits of comparing closed procedures with and without endoscopic assistance, underscoring the advantages of optical utilization.

Systematic review of cochlear implantation in patients with inner ear malformations.

Objectives: To evaluate the outcomes of cochlear implantation in patients with severe to profound sensorineural hearing loss due to inner ear malformations (IEMs) when compared to patients without IEMs. We discussed audiological outcomes such as open-set testing, closed-set testing, CAP score, and SIR score as well as postoperative outcomes such as cerebrospinal fluid gusher and incomplete insertion rate associated with cochlear implantation in individuals with IEMs.

Data Sources: PubMed, Science Direct, Web of Science, Scopus, and EMBASE databases.

Cochlear Implant Outcomes in Patients with Neurosarcoidosis.

Introduction: Audiovestibular symptoms are rare in sarcoidosis, but they may also be the first manifestation of the disease. Sudden or progressive bilateral hearing loss is usually associated with vestibular impairment. The mechanism of hearing loss remains unclear, but clinical presentation and magnetic resonance imaging suggest a retrocochlear site for the lesion in most patients.