Computational Fluid Dynamics Simulations to Personalize Nasal Irrigations.

: Proper nasal irrigation techniques are essential for treating nasal and sinus conditions, influencing drug delivery efficiency and patient comfort. This study evaluates how different head positions-upright, right-tilted, and left-tilted-affect the distribution of saline solution in the nasal cavity and maxillary sinus using computational fluid dynamics (CFD). : CFD simulations were conducted on a CT-based model of a healthy adult.

Sound-induced drug distribution in the cochlea, how close are we? A PRISMA scoping review.

Objective: To evaluate the efficacy of sound stimulation for enhancing drug distribution in the cochlea's perilymph, crucial for treating one of the most inaccessible organs and a major disability factor worldwide.

Design: A systematic scoping review following PRISMA guidelines was conducted, analysing studies on cochlear fluid dynamics influenced by sound stimulation. Data were collected from PubMed and Google Scholar using both MeSH and non-MeSH terms, with exclusions for unrelated topics.

Computational fluid dynamics (CFD), virtual rhinomanometry, and virtual surgery for neonatal congenital nasal pyriform aperture stenosis.

Objectives: Investigate the implications of Congenital Nasal Pyriform Aperture Stenosis (CNPAS) on neonatal nasal airflow through computational fluid dynamics (CFD), create a virtual rhinomanometry, and simulate the prospective outcomes post-virtual surgical intervention.

Methods: CT scanning of a neonate diagnosed with CNPAS and a control model were used to execute CFD simulations. The segmentation file of the CNPAS underwent manual modifications to simulate a virtual surgical procedure, resulting in a geometry that mirrors a post-operatively corrected patient.

Heliox simulations for initial management of congenital laryngotracheal stenosis.

Objectives: Congenital laryngotracheal stenosis is rare, potentially severe, and difficult to manage. Heliox is a medical gas effective in obstructive airway pathologies, given its physical properties. This study aims to model the interest of Heliox in reducing the respiratory work in congenital laryngotracheal stenosis, using numerical fluid flow simulations, before considering its clinical use.

Numerical simulation of nasal airflows and thermal air modification in newborns.

Warming, filtering, and humidification of inspired air are major functions of the upper airway, which can be negatively altered by local disorders or surgical interventions. These functions have not been described in neonates because of ethical and technical problems difficult to solve. Numerical simulations can get around these limitations.

Functional relevance of computational fluid dynamics in the field of nasal obstruction: A literature review.

Background: Nasal airway obstruction (nasal obstruction) is a common symptom affecting the quality of life of patients. It can be estimated by patient perception or physical measurements. Computational fluid dynamics (CFD) can be used to analyse nasal ventilation modalities.

Correlations between computational fluid dynamics and clinical evaluation of nasal airway obstruction due to septal deviation: An observational study.

Objectives: The primary objective of this study was to determine how computational fluid dynamics (CFD) could be correlated to clinical evaluation of nasal airway obstruction (NAO) in a population of patients with symptomatic septal deviation (SD). The secondary objective was to determine whether CFD could define which side was the more obstructed.

Design: This was an observational study.

A preliminary study of computer assisted evaluation of congenital tracheal stenosis: a new tool for surgical decision-making.

Objective: Congenital tracheal stenosis is a rare but severe condition with tracheal narrowing. There is no absolute correlation between luminal diameter and prognosis, and therapeutic decisions are difficult for intermediate cases. The aim of this study was to develop a dynamic model of the ventilatory consequences of congenital tracheal stenosis using computational fluid dynamics.