Publications by authors named "Chiyin Li"

Background: Persistent fatigue, often accompanied by neuropsychiatric symptoms (e.g., cognitive impairment, sleep disorders, depression, anxiety, and PTSD), commonly referred to as "long COVID".

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Post-traumatic stress symptoms (PTSS) have emerged as a prominent psychological consequence of the coronavirus disease 2019 (COVID-19) pandemic. Although early-stage fatigue is a known risk factor for developing PTSS, neural mechanisms linking fatigue and PTSS after COVID-19 infection remain unclear. In this study, we investigate whether dysfunctional fatigue-related brain functional connectivity during the acute phase is associated with PTSS in individuals with COVID-19 at 3-month follow-up.

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Introduction: Growing evidence suggests that corticospinal tract (CST) damage and microstructural integrity are key predictors of post-stroke motor impairment. However, their combined clinical utility-particularly in CST sub-pathways originating from non-primary motor cortical areas-remains underexplored. This study aimed to determine whether microstructural integrity and lesion load (LL) of each CST sub-pathway at 2 weeks predict motor outcomes at 2, 6, and 12 weeks post-stroke.

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Long COVID is characterized by debilitating fatigue, likely stemming from abnormal interactions among brain regions, but the neural mechanisms remain unclear. Here, we utilized a nested-spectral partition (NSP) approach to study the segregation and integration of resting-state brain functional networks in 34 patients with long COVID from acute to chronic phase post infection. Compared to healthy controls, patients with long COVID exhibited significantly higher fatigue scores and shifted the brain into a less segregated state at both 1 month and 3 months post infection.

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Background: Cognitive dysfunction after traumatic brain injury (TBI) significantly reduces quality of life and imposes a heavy burden on society. A detailed examination of research trends of cognitive dysfunction following TBI has not yet been conducted. This study aimed to examine the bibliometric analysis of cognitive dysfunction after traumatic brain injury over the past 20 years.

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Insomnia disorder is a significant global health concern. This research aimed to explore the pathogenesis of insomnia disorder using static and dynamic degree centrality methods at the voxel level. A total of 29 patients diagnosed with insomnia disorder and 28 healthy controls were ultimately included to examine differences in degree centrality between the two groups.

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Aims: To assess the prevalence of thrombophilia among Chinese women with venous thromboembolism (VTE) developed during pregnancy.

Methods: Based on information from a tertiary teaching unit, all recorded cases of deep vein thrombosis (DVT) and pulmonary embolism (PE) during pregnancy diagnosed between 1997 and 2005, were assessed for prevalence of thrombophilia. Fifty-five healthy women, who had at least one normal pregnancy but without any previous history of VTE, were recruited as controls.

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