Prevalence of preterm birth and risk factors associated with it at different gestational ages: A multicenter retrospective survey in China.

Objectives: To investigate the prevalence of preterm birth (PTB) and the risk factors for different gestational age subgroups of preterm birth in China.

Methods: We carried out a descriptive cross-sectional study encompassing all singleton live births (24 to 41 weeks) with completed data in 23 provinces in China from 2010 to 2017 during investigation period. We compared both the preterm group (24 to 36 weeks) and preterm subgroups (<32 weeks, 32 to 33 weeks, and 34 t0 36 weeks) with the term group (37 to 41 weeks).

Ancient DNA and multimethod dating confirm the late arrival of anatomically modern humans in southern China.

The expansion of anatomically modern humans (AMHs) from Africa around 65,000 to 45,000 y ago (ca. 65 to 45 ka) led to the establishment of present-day non-African populations. Some paleoanthropologists have argued that fossil discoveries from Huanglong, Zhiren, Luna, and Fuyan caves in southern China indicate one or more prior dispersals, perhaps as early as ca.

Pregnancy induced hypertension and outcomes in early and moderate preterm infants.

Objective: To identify the effect of pregnancy induced hypertension on neonatal outcomes in early and moderate preterm infants of gestational age less than 34 weeks.

Study Design: Prospectively collected data in 773 premature deliveries less than 34 weeks from 10 centers in China between July 2014 and July 2016 were analyzed in this cohort study. Univariate and Multivariate regression analyses were conducted to exam the effect of pregnancy induced hypertension on neonatal outcomes, including mortality to discharge, intrauterine growth restriction, severe brain injury, neonatal respiratory distress syndrome, bronchopulmonary dysplasia, necrotizing enterocolitis, early onset of sepsis and retinopathy of prematurity.

Effects of preweaning environmental enrichment on hippocampus-dependent learning and memory in developing rats.

Previous studies have shown that environmental enrichment (EE) improves learning and memory in adult animals. However, the effects of preweaning EE (preEE) on hippocampus-dependent learning and memory as well as its possible mechanisms are poorly understood. Here we report that preEE enhanced the exploratory activity in rats immediately after weaning, and the EE group showed greater performance in a passive avoidance task than the control group (p<0.

[Clinical features and follow-up study of neonatal asymmetric crying facies].

Objective: To evaluate the clinical characteristics and short-term outcomes of neonatal asymmetric crying facies (ACF), in order to improve recognition of the disease.

Methods: The clinical data of 11 infants with ACF between January 2010 and February 2012 were retrospectively studied. Physical and neurological development were followed up at correct gestational age 44 weeks and 3 months.

Calmodulin activation is required for the enhancement of hippocampal neurogenesis following environmental enrichment.

Objective: An enriched environmental exposure has been shown to promote hippocampal neurogenesis, which is an important mechanism underlying enrichment-induced memory improvement. The cAMP response element-binding protein is an important stimulus-inducible factor in the brain and is crucial for neurogenesis and memory ability. Calmodulin activation is important for activity-induced cAMP response element-binding protein phosphorylation.

[Effects of preweaning enrichment on activity-regulated cytoskeletal protein expression and long-term memory in rats].

Objective: To investigate the effects of preweaning enrichment on the expression of activity-regulated cytoskeletal protein (Arc), an immediate early gene, and on the long-term memory in rats.

Methods: Forty neonatal Sprague-Dawley rats were randomly assigned to control group (standard environment, n=20) and experimental group (enriched environment, n=20). The experimental group received enriched environment exposure from postnatal day 10 until weaning (2 weeks, 20 minutes per day).

[Preweaning exposure to enriched environment induces hippocampal neurogenesis: experiment with rats].

Objective: To explore the effects of preweaning exposure to enriched environment on hippocampal neurogenesis and the underlying mechanisms.

Methods: Thirty-six 10-day-old SD rats were randomly divided into the 2 equal groups: control group and enriched environment group (EE group. From the age of 10 days to 24 days the rats received intraperitoneal injection of bromodeoxyuridine (BrdU) 50 mg/kg every other day to label the newly proliferated cells in vivo, and the rats in EE group were daily exposed to enriched environment for 20 minutes.