Protocol: Scoping review of the association between complementary feeding, growth, and immune health in infants and toddlers-An EAACI guideline paper.

The European Academy of Allergy and Clinical Immunology (EAACI) is currently developing guidelines on immunomodulation and nutrition. To inform these recommendations, a scoping review will be conducted to synthesize and map the available empirical evidence on how complementary feeding affects immune health in infants and toddlers to explore the association between complementary feeding during the first year of life and immune health outcomes in children up to 3 years of age. The scoping review will be conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analysis Scoping Review Extension for scoping reviews (PRISMA-ScR) guidelines.

Guidance for healthy complementary feeding practices for allergy prevention in developed countries: An EAACI interest group report.

The goals of the complementary feeding period starting from 4 to 6 months of age are to fulfill the infant's nutritional need for nutrients and expose the infant to foods of varying flavors and textures to encourage acceptance of a diverse and nutritionally complete diet. Healthy complementary feeding consists of the timely introduction of a high diversity of whole, nutrient dense, and home-cooked foods or alternatively commercially frozen meals based on whole ingredients without added sugar or salt. These meals consist of predominantly plant-based foods, such as fruits, vegetables, legumes, grains, as well as fermented foods such as yoghurt.

Dietary and Nutritional Opportunities and Concerns for Patients with Food Allergy.

Individualized avoidance is the cornerstone of immunoglobulin E (IgE)-mediated food allergy (FA) management. Education on proper avoidance, including label reading, avoiding cross-contact, eating safely away from home, and alternatives, is paramount. Individuals with FAs are at increased risk for growth faltering, and the involvement of a dietitian to ensure the diet is complete is essential.

Parental Motivation for Introducing Babies' First Foods and Common Food Allergens.

Background/objectives: Findings from the Learning Early About Peanut trial prompted a shift in clinical practice guidelines to support the early and continuous introduction of allergenic foods to reduce the risk of food allergy. Our study aimed to describe the reasoning behind parents' decisions on the introduction of first foods to their infants and the age at which parents first introduced common allergens.

Methods: Parents of a child aged <18 years old with ≥1 food allergy, who lived in either Canada or the United States, were recruited via social media between March 2021 and February 2022 to participate in an online, anonymous survey.

The Impact of Rhinovirus, Syncytial Respiratory Virus and Helminth Infection on the Risk of New-Onset Asthma and Other Allergic Conditions-A Systematic Review for the EAACI Guidelines on Environmental Science for Allergic Diseases and Asthma.

This systematic review evaluated the association between lower respiratory tract infections (LRTI) in infancy with respiratory syncytial virus (RSV), rhinovirus (RV) or infestation with helminths and the risk of developing asthma and allergic diseases. The risk of bias was assessed with ROBINS-E, and the certainty of evidence (CoE) with GRADE. Meta-analysis applied a random-effects model.

Towards a common approach for managing food allergy and serious allergic reactions (anaphylaxis) at school. GALEN and EFA consensus statement.

GALEN and EFA propose minimum specifications for all industrialised countries/regions to work towards to support students with food allergies in educational settings. We reviewed research and legislation and gained feedback from over 100 patient and professional groups. We built shared expectations around: 1.

Prevalence and possible causes of crying and mild gastrointestinal and skin symptoms in infants reported by healthcare professionals - worldwide data.

Objective: Many infants experience crying, mild gastrointestinal (GI) symptoms (such as regurgitation, constipation, and diarrhea) and skin symptoms during the first year of life. However, little is known about the prevalence and the management of these symptoms. The aim of this study was to gather insights in the experiences, prevalences, and potential causes of mild-to-moderate crying and GI and skin symptoms in healthy infants (< 12 months) as reported by health care professionals (HCPs) globally.

Evaluating the Need for Pre-CoMiSS™, a Parent-Specific Cow's Milk-Related Symptom Score: A Qualitative Study.

: Cow's milk allergy (CMA) presents a significant clinical burden. The Cow's Milk-related Symptom Score (CoMiSS™) is a widely used clinical screening tool designed to raise awareness of CMA among healthcare professionals. This qualitative study aimed to assess the need for a parent-reported CoMiSS™ tool (Pre-CoMiSS™) and explore its potential usefulness for parents and primary care physicians (PCPs).

Oral Immunotherapy in Peanut-Allergic Adults Using Real-World Materials.

Background: Peanut oral immunotherapy (OIT) has shown effectiveness in achieving desensitization of children; however, evidence in adults is lacking.

Methods: This phase II trial evaluated peanut OIT in peanut-allergic adults using real-world peanut products. A Simon's minimax two-stage design, incorporating a stop:go for futility, was employed.

Systematic review of feeding difficulties in children with eosinophilic esophagitis: An EAACI Task Force report.

The term "feeding difficulties" (FD) encompasses a range of phenotypes characterized by inadequate food intake and/or inappropriate eating habits for a given age. Eosinophilic esophagitis (EoE) is a chronic, immune-mediated condition often affecting children. It leads to esophageal dysmotility, potentially impacting feeding/eating.

Corrigendum: The future of cow's milk allergy - milk ladders in IgE-mediated food allergy.

[This corrects the article DOI: 10.3389/fnut.2024.

Emerging concepts in introducing foods for food allergy prevention.

Purpose Of Review: This review focuses on the latest information regarding the role of complementary feeding practices and food allergen introduction in the prevention of food allergies.

Recent Findings: Early introduction of food allergens for food allergy prevention is recommended by food allergy prevention guidelines and is supported by the latest randomized controlled trials. Diet diversity is recommended, supported by the latest studies from Asia.

Clinical Presentation and Nutrition Management of Non-IgE-Mediated Food Allergy in Children.

Non-IgE-mediated food allergy encompasses a wide spectrum of allergic disorders ranging from mild to severe presentations, including food protein-induced allergic proctocolitis, food protein-induced enterocolitis syndrome, and food protein-induced enteropathy. Other gastrointestinal symptoms such as constipation and gastroesophageal reflux disease have not previously been recognised as symptoms of non-IgE-mediated food allergy in food allergy guideline publications. Recently, two new consensus documents from the European Academy of Allergy, Asthma and Immunology address a potential role of food allergens in these disorders, where standard treatment has failed, and provide guidance for diagnosis and management of these conditions.

Diversity of complementary diet and early food allergy risk.

Introduction: Diet diversity (DD) in infancy may be protective for early food allergy (FA) but there is limited knowledge about how DD incorporating consumption frequency influences FA risk.

Methods: Three measures of DD were investigated in 2060 infants at 6 and/or at 9 months of age within the NorthPop Birth Cohort Study: a weighted DD score based on intake frequency, the number of introduced foods, and the number of introduced allergenic foods. In multivariable logistic regression models based on directed acyclic graphs, associations to parentally reported physician-diagnosed FA at age 9 and 18 months were estimated, including sensitivity and stratified analyses.

Food Allergy Prevalence in Two Population-Based UK Cohorts Born 12 Years Apart.

Background: Adverse food reactions include food allergy (FA; immune-mediated) and food intolerances (non-immune-mediated). FA are classified into IgE- and non-IgE-mediated FA. There is limited information available about changes in FA prevalence over time.

Systematic review on maternal dietary patterns during pregnancy and offspring allergy.

Allergic diseases including food allergy, atopic dermatitis, asthma, and allergic rhinitis are increasing. Nutritional intake may play a role in this increase. Systematic reviews indicate that intake of specific nutrients and foods does not prevent allergic diseases.

10 practical priorities to prevent and manage serious allergic reactions: GALEN ANACare and EFA Anaphylaxis Manifesto.

This Anaphylaxis Manifesto calls on communities to prioritise 10 practical actions to improve the lives of people at risk of serious allergic reactions. The Global Allergy and Asthma European Network and the European Federation of Allergy and Airways Diseases Patients' Associations (EFA) compiled patient-centric priorities. We used qualitative consensus methods, research evidence and feedback from over 200 patient groups, stakeholder organisations and healthcare professionals.

The evolution of nutritional care in children with food allergies - With a focus on cow's milk allergy.

Cow's milk allergy (CMA) remains one of the most common and complex paediatric food allergies. In the last decade, our understanding has advanced in terms of immunoglobulin E (IgE)-mediated CMA and focus is now also paid to non-IgE-mediated CMA, particularly in some Western countries where incidence rates are high. We have had significant progress in the last 10 years in relation to our understanding of existing supportive tests for IgE-mediated CMA, with the advancement of newer tests, such as the basophil activation test (BAT), which have shown great promise.

Validation of a Food Frequency Questionnaire: VioScreen-Allergy.

Background/objectives: An adapted version of an online pictorial food frequency questionnaire (FFQ), VioScreen-Allergy, assesses total dietary intake and intake of allergens and foods in the maternal diet index (MDI), linked to offspring allergy. This study assessed intermethod reliability, test-retest reliability, and external validity of the VioScreen-Allergy.

Methods: Females of childbearing age were recruited at Denver Health and Children's Hospital, Colorado, USA, and were asked to complete four 24 h recalls and two VioScreen-Allergy FFQs over the course of a month.