Revisiting the Role of Soy Formula for Infants With IgE-Mediated Cow's Milk Allergy.

Cow's milk allergy is one of the most commonly reported food allergies in infancy and early childhood. Although extensively hydrolyzed formulas and then amino acid-based formulas are the current standard of care, soy-based formula represents a less costly and more palatable alternative. Some cited concerns about soy-based formula include potential phytoestrogen-related effects and coallergy with cow's milk.

Introduction of allergenic foods after treatment with omalizumab.

Background: Omalizumab has been shown to increase reaction thresholds to allergenic foods during treatment. Little is known about its potential to permit introduction of allergenic foods.

Objective: The aim of this study was to examine introduction of allergenic foods after stopping treatment with omalizumab.

Emerging concepts in introducing foods for food allergy prevention.

Purpose Of Review: This review focuses on the latest information regarding the role of complementary feeding practices and food allergen introduction in the prevention of food allergies.

Recent Findings: Early introduction of food allergens for food allergy prevention is recommended by food allergy prevention guidelines and is supported by the latest randomized controlled trials. Diet diversity is recommended, supported by the latest studies from Asia.

Clinical Presentation and Nutrition Management of Non-IgE-Mediated Food Allergy in Children.

Non-IgE-mediated food allergy encompasses a wide spectrum of allergic disorders ranging from mild to severe presentations, including food protein-induced allergic proctocolitis, food protein-induced enterocolitis syndrome, and food protein-induced enteropathy. Other gastrointestinal symptoms such as constipation and gastroesophageal reflux disease have not previously been recognised as symptoms of non-IgE-mediated food allergy in food allergy guideline publications. Recently, two new consensus documents from the European Academy of Allergy, Asthma and Immunology address a potential role of food allergens in these disorders, where standard treatment has failed, and provide guidance for diagnosis and management of these conditions.

Peanut Oral Immunotherapy in Children with High-Threshold Peanut Allergy.

Background: Approved therapeutics for peanut allergy are not designed for the many patients with allergic reactions to more than one peanut.

Methods: We randomly assigned (1:1) participants 4 to 14 years of age reacting to a challenge of between 443 mg and 5043 mg of peanut protein to peanut oral immunotherapy (P-OIT) using home-measured peanut butter versus peanut avoidance. The primary end point was the difference between groups in the proportion tolerating a two-dose-level increase or 9043 mg of peanut protein.

The evolution of nutritional care in children with food allergies - With a focus on cow's milk allergy.

Cow's milk allergy (CMA) remains one of the most common and complex paediatric food allergies. In the last decade, our understanding has advanced in terms of immunoglobulin E (IgE)-mediated CMA and focus is now also paid to non-IgE-mediated CMA, particularly in some Western countries where incidence rates are high. We have had significant progress in the last 10 years in relation to our understanding of existing supportive tests for IgE-mediated CMA, with the advancement of newer tests, such as the basophil activation test (BAT), which have shown great promise.

The Multiple Facets of Cow's Milk Allergy.

Cow's milk allergy (CMA) is one of the most common food allergies in early childhood. CMA has varied presentations and multiple facets. A detailed clinical history is key for classification.

World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update - XVI - Nutritional management of cow's milk allergy.

Cow's milk allergy (CMA) is one of the most common presentations of food allergy in early childhood. Management of CMA involves individualized avoidance of cow's milk and other mammalian milk and foods containing these. Optimal elimination of cow's milk avoidance includes: label reading; information about safe and nutritious substitute foods; appropriate choice of infant formula or a plant-based food; establishing tolerance to baked milk and monitoring nutritional intake and growth.

Awareness and Application of United States Food Allergy Prevention Guidelines Among Pediatricians and Other Clinicians.

Objective: To characterize the awareness of, adherence to, and barriers to the 2017 National Institute of Allergy and Infectious Diseases (NIAID) peanut allergy prevention guidelines among the pediatrics health care workforce.

Study Design: Pediatricians, family physicians, advanced practice providers (APPs), and dermatologists who provide care for infants were solicited for a population-based online survey, administered from June 6, 2022, through July 3, 2022. The survey collected information about NIAID guideline awareness, implementation, and barriers as well as concerns related to the guidelines.

Nutritional management of food allergies.

Food allergy is a significant public health concern, with a rising prevalence. Elimination diets remain the cornerstone of food allergy management, and they are not without nutritional risk. Children who avoid nutritionally important foods, such as milk or multiple foods allergens, may be at greater risk.

The role of dietitians and psychologists to promote optimum patient related outcomes in oral immunotherapy.

Although research in oral immunotherapy for food allergy is perceived primarily as a biomedical endeavor, the involvement of multiple disciplines is required to ensure optimum outcomes for patients and their caregivers. This is a narrative review of research in which we also provide expert opinion due to the small number of studies addressing the role of dietitians and psychologists in oral immunotherapy to foods. Dietitians support patient education with instructions on how to measure and prepare the immunotherapy dose, incorporate the dose into the daily diet, and transition to equivalent foods to meet dosing needs.

Dietary Management of Eosinophilic Esophagitis.

Eosinophilic esophagitis (EoE) is a chronic immune-mediated food allergy-driven disease characterized by eosinophilic inflammation of the esophagus leading to symptoms of esophageal dysfunction. Prior studies have supported the key role of food allergen exposure as the main driver behind the etiopathogenesis showing that removal of food antigens can result in disease remission in both children and adults. These landmark studies serve as the basis for the rising interest and evolution of dietary therapy in EoE.

Age-Related Food Aversion and Anxiety Represent Primary Patient Barriers to Food Oral Immunotherapy.

Background: Although oral immunotherapy (OIT) for food allergy is a reasonable treatment option, barriers to this procedure's implementation have not been extensively evaluated from a patient perspective.

Objective: We evaluated the barriers patients face during OIT administration, including anxiety and taste aversion, and the role of health care professionals, especially dietitians.

Methods: A survey in Canada and the United States involved families currently enrolled in food OIT programs.

Identifying Children at Risk of Growth and Nutrient Deficiencies in the Food Allergy Clinic.

Background: Food allergies affect growth in children by decreasing the availability of nutrients through decreased dietary intake, increased dietary needs, food-medication interactions, and psychosocial burden. Guidelines on food allergy management frequently recommend nutrition counseling and growth monitoring of children with food allergies.

Objective: To provide clear guidance for clinicians to identify children with food allergies who are at nutritional risk and ensure prompt intervention.