Dermal Filler Use in Patients Undergoing Chemotherapy and Radiation Therapy.

Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in patients with cancer undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population.

Efficacy of gamma knife radiosurgery for cerebral cavernous malformations - A single-institution retrospective study.

Background: Cerebral cavernous malformations (CCMs) are low-flow vascular malformations of the central nervous system. Although surgical resection is the primary treatment for symptomatic CCMs, gamma knife radiosurgery (GKRS) has been considered as an alternative treatment for CCMs with high surgical risk. This study aims to evaluate outcomes of GKRS in the treatment of CCMs.

Respiratory complications following minimally invasive esophagectomy: associated factors and predictive value of lung age.

Background: Postoperative complications following esophageal surgery are severe, with respiratory complications being the most common. This study aims to evaluate the rate of respiratory complications and related factors post-esophagectomy and lymph node dissection for esophageal squamous cell carcinoma (ESCC).

Subjects And Methods: A prospective cross-sectional study was conducted from October 2022 to March 2024 on ESCC who underwent minimally invasive esophagectomy and extended two-field lymph node dissection.

Association of single-nucleotide polymorphism with spirometry indices and pulmonary ventilation characteristics in patients with chronic obstructive pulmonary disease.

ObjectivesGenome-wide association studies have identified as a gene linked to chronic obstructive pulmonary disease. Several single-nucleotide polymorphisms-notably, rs7671167, rs2869967, rs2869966, and rs17014601-are associated with chronic obstructive pulmonary disease susceptibility and spirometric indices. This study aimed to investigate the association between single-nucleotide polymorphisms and spirometric indices in chronic obstructive pulmonary disease and non-chronic obstructive pulmonary disease patients and assess the correlation of these single-nucleotide polymorphisms with pulmonary ventilation function.

Characterization of DNA Viruses in Hindgut Contents of Larvae.

The scarab species , an edible insect, has been used in traditional medicine, as animal feed, and for converting agricultural organic wastes into biofertilizer. The intestinal tract, which contains a diverse array of microbiota, including viruses, plays a critical role in animal health and homeostasis. We previously conducted a comparative analysis of the gut microbiota of third-instar larvae of obtained from five different farms and found significant differences in the composition of the gut bacterial microbiota between farms.

Gender gap in physical activity and sport participation across the lifespan in Australia between 2016 and 2023.

Background: The primary aim of this study was to examine the gender gap in specific types of leisure-time physical activity (including sport and active recreation) in Australians across the lifespan from 2016 to 2023. The secondary aim of this study was to examine trends in participation in specific types of leisure-time physical activity from 2016 to 2023.

Methods: This repeated cross-sectional study included sport and active recreation data from Ausplay (2016–2023) from a representative sample of participants aged five years and above in Australia.

Cumulative impacts of interbasin water transfer and salinity intrusion on water security in central Vietnam.

Saltwater intrusion poses a significant threat to freshwater availability in downstream regions globally, leading to economic losses, compromised water supply, reduced agricultural productivity, social instability, and environmental degradation. This study assesses the extent and drivers of salinity intrusion in the downstream areas of the Vu Gia Thu Bon River basin, central Vietnam, with a particular focus on Da Nang City. The analysis considers the impacts of upstream dam operations and inter-basin water transfers on water supply and irrigation, encompassing both direct and indirect damages.

Percutaneous transhepatic biliary stone removal in patients with prior bile duct stents: Report of 2 cases.

Gallstones with bile duct stones in patients with prior stent placement challenge traditional endoscopic or surgical management, particularly in high-risk individuals. Percutaneous transhepatic biliary stone removal (PTBD) offers a minimally invasive alternative, but its role in this population is underexplored. This case series assesses PTBD's efficacy and feasibility.

Analysis of HPV and NKG2D rs1049174 Polymorphism in Vietnamese Patients With Oropharyngeal Squamous Cell Carcinoma.

IntroductionOropharyngeal Squamous Cell Carcinoma (OPSCC) etiology involves environmental and genetic factors, with Human Papillomavirus (HPV) being a key ecological driver. This study evaluated the relative importance of environmental factors, particularly HPV status, and the genetic polymorphism NKG2D rs1049174 in OPSCC among a Vietnamese population.MethodsA retrospective case-control study was conducted with 279 OPSCC patients and 250 healthy controls.

Impact of Case Detection and Covid-19-Related Disruptions on Tuberculosis In Vietnam: A Modelling Analysis.

Background: Vietnam, a high-burden tuberculosis (TB) country, experienced marked declines in TB notifications during the COVID-19 pandemic. We assessed the impact of pandemic-related disruptions on TB case detection and transmission using a dynamic transmission model calibrated to local demographic and epidemiological observations.

Methods: We developed an age-structured compartmental TB transmission model to estimate COVID-19's impact on TB in Vietnam.

Structural polymorphism of ALECT2 amyloid fibrils revealed by cryo-EM.

ALECT2 amyloidosis is a rare systemic disease characterized by the pathological deposition of leukocyte cell-derived chemotaxin-2 (LECT2) as amyloid fibrils, primarily affecting the kidneys and liver. The molecular mechanisms underlying LECT2 aggregation remain poorly defined, hindering diagnostic and therapeutic development. Here, we present cryo-electron microscopy structures of ALECT2 fibrils extracted from a patient's kidney.

A Screening Protocol to Identify Older Adults With Dementia and Their Family Caregivers in Northern Vietnam.

Objectives: Alzheimer's disease and related dementias (ADRD) pose a growing public health challenge in Vietnam. This study describes a community-based screening protocol to identify older adults and their primary family caregivers in Hai Duong province to support recruitment for a caregiver intervention clinical trial.

Methods: Village health workers were trained to identify older adults at risk for dementia using a simplified tool adapted from the California Alzheimer's Disease Centers' Assessment of Cognitive Complaints Toolkit.

ACLY inhibition promotes tumour immunity and suppresses liver cancer.

Immunosuppressive tumour microenvironments are common in cancers such as metabolic dysfunction-associated steatohepatitis (MASH)-driven hepatocellular carcinoma (HCC) (MASH-HCC). Although immune cell metabolism influences effector function, the effect of tumour metabolism on immunogenicity is less understood. ATP citrate lyase (ACLY) links substrate availability and mitochondrial metabolism with lipid biosynthesis and gene regulation.

Berberine Reveals Anticoccidial Activity by Influencing Immune Responses in -Infected Chickens.

Serious enteric disease caused by seven species of continues to cause significant economic damage to the poultry industry. is one of the most widespread strains in farms and has a significant impact on chicken weight loss. Currently, the use of anticoccidial agents to suppress the occurrence of coccidiosis in farms is considerably restricted due to public health and environmental pollution issues.

Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis.

Background: Despite the rapid increase in evidence from the past decade on daily steps and health-related outcomes, existing systematic reviews primarily focused on few outcomes, such as all-cause mortality. This study synthesised the prospective dose-response relationship between daily steps and health outcomes including all-cause mortality, cardiovascular disease, cancer, type 2 diabetes, cognitive outcomes, mental health outcomes, physical function, and falls.

Methods: For this systematic review and meta-analysis, we searched PubMed and EBSCO CINAHL for literature published between Jan 1, 2014, and Feb 14, 2025, supplemented by other search strategies.

Efficacy of Oral Midazolam for Sedation and Amnesia in Preschool Children with Dental Anxiety: A Double-Blind, Randomized Controlled Trial.

: Dental anxiety often poses a significant barrier to effective dental care in pediatric patients. This study evaluated the efficacy and safety of oral midazolam at two different doses for sedation and amnesia in preschool children undergoing dental procedures under 30 min, including primary teeth extraction, root canal treatment, dental filling, and stainless-steel crown. : This prospective, double-blind, randomized controlled trial included 80 children aged 3-6 years with dental anxiety (Types 1 and 2 of the Frankl Behavior Rating Scale) at the National Hospital of Odonto-Stomatology, Hanoi.

Hepatitis C virus incidence trend and its risk factors among people who inject drugs in Hai Phong, Vietnam.

Background: HCV incidence among people who inject drugs (PWID) remains unacceptably high. Using the data from the DRIVE study, we aimed to describe HCV incidence trends and investigate its associated risk factors among PWID in Hai Phong, Vietnam.

Methods: Active PWID were recruited through 3 annual respondent-driven sampling (RDS) surveys; part of them were included in the study cohorts.

Optimal dosing and duration of linezolid for the treatment of multidrug-resistant and rifampicin-resistant tuberculosis: an individual patient data meta-analysis.

Background: The optimal dosing strategy of linezolid for treating multidrug-resistant and rifampicin-resistant tuberculosis remains unclear. We conducted an individual patient data meta-analysis to determine the optimal linezolid dosing strategy.

Methods: We searched for randomised controlled trials and prospective cohort studies on short-course all‑oral regimens containing linezolid for treating multidrug-resistant and rifampicin-resistant tuberculosis in PubMed, Embase and Scopus up to 31 August 2023.

Characteristics of kinase domain mutations in Vietnamese chronic myeloid leukemia patients.

Background: kinase domain (KD) mutations represent a common cause of resistance to tyrosine kinase inhibitors in chronic myeloid leukemia (CML) patients. The frequency and pattern of KD mutations differ among populations worldwide. However, the characteristics of KD mutations in Vietnamese patients remain unclear.

Machine learning-based detection of changes in mapping the mangrove forest of the Yangon estuary, Southeast Asia.

Mangrove forests are globally acknowledged for stabilizing coastlines, reducing wave energy, and protecting coastal habitats and adjacent land uses from extreme events. However, most regions experience alarming mangrove loss against natural and human disturbances. This study profiles dynamic changes in mangrove cover and shoreline migration along the Yangon estuary using Landsat imagery and machine learning approach from 1988 to 2023.

Long-term outcomes among people with multi-drug resistant tuberculosis in Vietnam: a prospective cohort study.

Introduction: Existing rates of death and recurrent TB among people treated for rifampicin- or multidrug-resistant tuberculosis (RR/MDR-TB) are likely underestimates. We determined long-term disease outcomes among a cohort of people treated for RR/MDR-TB.

Methods: We conducted a prospective cohort study among patients treated by the National TB Program (NTP) in ten provinces of Vietnam.

Mapping mangrove multi-trait functional diversity from satellite observations across dense and fragmented stands using spectral-biophysical derivatives.

Occupying critical ecological areas at the land-sea interface, mangrove ecosystems are increasingly recognized as potent nature-based solutions supporting diverse sustainable development goals. Leveraging spatially explicit remote sensing for monitoring mangrove biodiversity is essential, however, measurement challenges arise due to their narrow and fragmented distribution over impenetrable muddy substrates compared to terrestrial forests. This study presents the first attempt to map mangrove functional diversity (FD) using a multi-trait-based approach, incorporating key spectral vegetation indexes as well as optically derived functional traits: leaf chlorophyll content (LCC), leaf mass per area (LMA), and equivalent water thickness (EWT) retrieved from Sentinel-2.

Stabilisation of PRCP by deubiquitinase-targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy.

Background And Purpose: Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1-7, has an unclear role in cardiac autophagy and hypertrophy.

Bifenazate as compatible acaricide for biocontrol agent Transeius montdorensis (Acari: Phytoseiidae).

Background: Integrated pest management strategies often include the use of pesticides that have minimal impact on biological control agents. The predatory mite Transeius montdorensis is a valuable agent for controlling whiteflies, thrips and spider mites, but its tolerance to commonly used pesticides is not well understood. This study aims to investigate the genetic basis of pesticide tolerance in Transeius montdorensis.

Impact and cost-effectiveness of interventions to eliminate hepatitis C virus among people who inject drugs in Haiphong, Vietnam.

Background: In Haiphong, Vietnam, most hepatitis C virus (HCV) infections occur among people who inject drugs (PWID). As part of multiple respondent-driven sampling (RDS) surveys among PWID in Haiphong, an intervention (DRIVE-C) provided HCV testing and treatment in 2019. Centres providing opiate agonist treatment (OAT) or antiretroviral therapy (ART) also provided HCV testing and linkage-to-treatment in 2021/22.