Exploring clinical and demographic determinants of time to treatment in spinal metastases: A Large-Scale cohort study of more than 1000 patients.

Objective: To identify predictors for time to first treatment modality (TTT) in patients diagnosed with spinal metastatic disease.

Methods: Our radiology database was retrospectively queried to identify patients with spinal metastases (01/2017-12/2021). Demographics, setting of initial imaging (inpatient/outpatient/ED), histology, treatment modality, and TTT were collected.

Platelet transfusions and outcomes following minimally invasive intracerebral hemorrhage evacuation.

Objective: Minimally invasive evacuation has emerged as a promising treatment paradigm for spontaneous intracerebral hemorrhage (ICH). Preoperative platelet transfusion to reduce the risk of perioperative hemorrhage remains controversial, given that it can increase clot fibrosity, leading to a more difficult-to-resect hematoma and worse clinical outcome without appreciably reducing the risk of perioperative hemorrhage. To evaluate this hypothesis, the authors developed and prospectively applied a qualitative scale rating the consistency of intraoperative hematoma and then assessed the association of the scale with platelet transfusion, evacuation percentage, functional outcome, and postoperative rebleeding.

Analysis of the interaction between sleep quantity and sex in neurocognitive performance testing for sports-related concussion.

Objective: Cognitive testing for sports-related concussion (SRC) has become a critical component in ensuring the health of adolescent athletes. Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a validated tool for assessing SRC and guiding subsequent medical management; thus the effect of different variables on ImPACT scoring is of clinical relevance. The aim of this study was to evaluate the influence of sleep quantity and patient sex on the ImPACT performance of athletes at baseline and time points after SRC.

Optimizing Intracerebral Hemorrhage Management and Interhospital Transfer With Viz ICH Plus AI Technology.

This case study explores the integration of Viz ICH Plus, an AI-powered intracerebral hemorrhage (ICH) detection system, into a centralized program called the Neuroemergencies Management and Transfer (NEMAT) program of a large urban healthcare system. The study highlights how Viz ICH Plus promptly identified a right parieto-occipital hematoma in a patient presenting with a headache, resulting in a marked reduction in interhospital transfer (IHT) time. The patient underwent a successful supratentorial craniotomy for hematoma evacuation and demonstrated significant cognitive and physical improvement over the following year.

Single-Institution Retrospective Propensity Score-Matched Comparative Cost Analysis of Multilevel Anterior Cervical Discectomy and Fusion versus Posterior Cervical Decompression and Fusion in Geriatric Patients with Cervical Disc Herniation.

Background: Despite the surge in anterior cervical discectomy and fusion (ACDF) and posterior cervical decompression and fusion (PCDF) procedures over the past 2 decades, there remains a paucity of data on their comparative costs in geriatric patients with cervical disc herniation. This study provides a comprehensive cost analysis of ACDF and PCDF in this patient population.

Methods: A total of 282 geriatric patients who underwent ACDF or PCDF for cervical disc herniation over a 12-year period were analyzed to assess total surgical costs, including preoperative, procedural, and postoperative expenses.

Effect of Sleep Duration and Concussion History on Neurocognitive Testing Symptoms for Post-injury States.

Objective: Evaluate the influence of sleep duration and concussion history on postconcussion symptoms in adolescent athletes.

Design: Observational retrospective study using the Immediate Post-Concussion Assessment and Cognitive Testing and Post-Concussion Symptom Scale (PCSS). Multivariable linear regression assessed sleep hours against 22 PCSS symptoms, controlling for demographic and health variables.

Systematic Review of Surgical Success, Complications, Revision Rates, Radiation Dosage, and Operative Time of 3D-Navigated versus Non-Navigated Spinal Procedures.

Objective: Three-dimensional (3D) navigation offers real-time guidance in surgery. However, there is limited and inconsistent data regarding the usability, safety, and efficacy. To address gaps in knowledge about 3D navigation in spinal surgery, we conducted a comprehensive review of success rates, complications, revisions, radiation exposure, and operative time associated with Federal and Drug Administration-approved 3D surgical navigation tools.

Anterior Cervical Discectomy and Fusion Associated with Increased Home Discharge Rates in Geriatric Patients with Cervical Disc Herniation Compared to Posterior Cervical Decompression and Fusion: A Propensity-Matched Analysis.

Introduction: Cervical disc herniation often necessitates surgery in elderly patients when nonoperative treatments fail. This study compares discharge outcomes of anterior cervical discectomy and fusion (ACDF) vs. posterior cervical decompression and fusion (PCDF) in geriatric patients.

Stress hyperglycemia is associated with longer ICU length of stay after endoscopic intracerebral hemorrhage evacuation.

Background: Stress hyperglycemia has been linked to poor outcomes in intracerebral hemorrhage (ICH). Recent studies using the ratio of blood glucose to glycated hemoglobin (HbA1c) as a marker for stress hyperglycemia have demonstrated greater discriminative power in predicting poor outcomes for stroke inpatients compared to blood glucose alone. Therefore, we aimed to investigate whether the preoperative glucose-to-HbA1c ratio is a predictor of postoperative outcomes in patients who have undergone minimally invasive ICH evacuation.

Molecular profile and clinical outcome of adult primary spinal cord glioblastoma: a systematic review.

Objective: Primary spinal cord glioblastoma (scGB) is a rare and aggressive spinal glioma, making up 7.5% of such cases. Whereas molecular profiles associated with improved overall survival (OS) are well studied for cranial glioblastoma (GB), the molecular characteristics of scGB are less documented.

Managing medically refractory elevated intracranial pressure in a pediatric patient on ECMO: illustrative case.

Purpose: We demonstrate the complexities of managing pediatric patients on extracorporeal membrane oxygenation (ECMO) therapy requiring neurosurgery, focusing on systemic anticoagulation, cardiac function, and medically refractory intracranial pressure (ICP).

Methods: A 3.5-year-old female with Tetralogy of Fallot developed severe ischemic cerebral edema following post-operative cardiac arrest and required ECMO.

Antithrombotics alter intracerebral hemorrhage presentation without affecting minimally invasive endoscopic evacuation.

Objectives: Intracerebral hemorrhages are associated with significant morbidity and mortality. While the ENRICH trial supports the efficacy of surgical evacuation for lobar hemorrhages, the impact of antithrombotic therapies on minimally invasive surgery outcomes remains unexplored. This study evaluates the effects of chronic anticoagulants and antiplatelets on the technical and longterm outcomes of minimally invasive intracerebral hemorrhage evacuation.

What is the cognitive footprint of insular glioma?

Cognitive impairment has a profound deleterious impact on long-term outcomes of glioma surgery. The human insula, a deep cortical structure covered by the operculum, plays a role in a wide range of cognitive functions including interceptive thoughts and salience processing. Both low-grade (LGG) and high-grade gliomas (HGG) involve the insula, representing up to 25% of LGG and 10% of HGG.

Bibliometric and trend analysis of the top 100 most-cited articles on lateral interbody fusion (LIF).

Purpose: Lateral interbody fusion (LIF) is an increasingly popular minimally-invasive spine procedure. This study identifies notable trends in LIF literature and provides a detailed review of the bibliometric aspects of the top 100 most-cited articles.

Methods: Articles were queried from the Web of Science database.

Return to play after head injury in adolescent sports: evaluating football versus other sports.

Objective: Increased adolescent sports participation has raised concerns about higher rates of concussions, a prevalent injury among young athletes with potential long-term effects. Discrepancies in concussion recovery and management protocols across various sports underscore a critical issue in youth athletics. This study aimed to examine the relationship between sport type and the number of games missed following a concussion to inform targeted management strategies.

Effects of hours of sleep on ImPACT concussion testing: comparing baseline with postinjury scores.

Objective: The influence of sleep on baseline and postconcussion neurocognitive performance prior to Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is poorly understood. Since ImPACT is widely used in youth sport to assess neurocognitive performance before and after head injury, it is important to delineate factors that affect testing performance. While some have reported correlations between fewer hours of sleep and lower scores on baseline tests, others have not observed any such associations.

The Top 100 Cited Articles on Cervical Disc Arthroplasty: A Bibliometric Analysis.

Study Design: Bibliometric analysis.

Objective: Cervical disc arthroplasty (CDA) has emerged as an effective surgical intervention for degenerative cervical disc disease with potential advantages over traditional cervical fusion. This bibliometric analysis aimed to assess the current state of research on CDA by analyzing the relevant literature using bibliometric indicators.

The 100 Top-Cited Articles on Robotic Neurosurgery: A Bibliometric Analysis.

Background: Robotic neurosurgery is a rapidly advancing field with numerous applications in various subspecialties, including spine, functional, skull base, and cerebrovascular. This study aims to provide a comprehensive analysis of the most-cited articles on robotic neurosurgery.

Methods: The Web of Science database was used to collect data, and bibliometric analysis was performed using VOSviewer and RStudio.

Correction to: Mechanical and functional validation of a perfused, robot-assisted partial nephrectomy simulation platform using a combination of 3D printing and hydrogel casting.

The Eqs. 1, 2 and 3 come under the section "Kidney cortex testing" as per the original manuscript, but they have been incorrectly moved and separated into different sections in the original publication of the article.

Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis.

Conventional hemodialysis (HD) uses floor-standing instruments and bulky dialysis cartridges containing ≈2 m of 10 micrometer thick, tortuous-path membranes. Portable and wearable HD systems can improve outcomes for patients with end-stage renal disease by facilitating more frequent, longer dialysis at home, providing more physiological toxin clearance. Developing devices with these benefits requires highly efficient membranes to clear clinically relevant toxins in small formats.

Mechanical and functional validation of a perfused, robot-assisted partial nephrectomy simulation platform using a combination of 3D printing and hydrogel casting.

Introduction And Objectives: There is a scarcity of high-fidelity, life-like, standardized and anatomically correct polymer-based kidney models for robot-assisted partial nephrectomy (RAPN) simulation training. The purpose of this technical report is to present mechanical and functional testing data as evidence for utilizing a perfused hydrogel kidney model created utilizing 3D printed injection casts for RAPN simulation and training.

Methods: Anatomically correct, tumor-laden kidney models were created from 3D-printed casts designed from a patient's CT scan and injected with poly-vinyl alcohol (PVA).

Incorporation and validation of clinically relevant performance metrics of simulation (CRPMS) into a novel full-immersion simulation platform for nerve-sparing robot-assisted radical prostatectomy (NS-RARP) utilizing three-dimensional printing and hydrogel casting technology.

Objectives: To incorporate and validate clinically relevant performance metrics of simulation (CRPMS) into a hydrogel model for nerve-sparing robot-assisted radical prostatectomy (NS-RARP).

Materials And Methods: Anatomically accurate models of the human pelvis, bladder, prostate, urethra, neurovascular bundle (NVB) and relevant adjacent structures were created from patient MRI by injecting polyvinyl alcohol (PVA) hydrogels into three-dimensionally printed injection molds. The following steps of NS-RARP were simulated: bladder neck dissection; seminal vesicle mobilization; NVB dissection; and urethrovesical anastomosis (UVA).