Transcatheter atrial septal defects and patent foramen ovale closure: Medicare utilization and reimbursements.

Background: The Food and Drug Administration has approved percutaneous atrial septal defect (ASD) and patent foramen ovale (PFO) closure devices for hemodynamically significant interatrial shunts, paradoxical emboli including stroke, and decompression sickness. We aimed to study the trends in utilization and reimbursements of transcatheter ASD/PFO closure devices.

Aim: To analyze trends in utilization and Medicare reimbursements for transcatheter ASD/PFO closure procedures from 2013 to 2022.

NMR-Based Metabolomics Reveals Metabolic Pathway Disruptions and Potential Biomarkers for Fibrosis.

The landscape of chronic liver disease has changed significantly, with metabolic dysfunction-associated steatotic liver disease (MASLD) now emerging as the most widespread form worldwide. In Asia, particularly in India, the prevalence of MASLD is increasing, largely driven by poor dietary habits and a sedentary way of life. MASLD spans from fat deposition to inflammation and fibrosis.

Incidence, Risk Factors, and Complications of Dysphagia in Stroke Patients Admitted to Medical Wards at a Tertiary Hospital in South India.

Background: Stroke patients commonly have dysphagia that can lead to aspiration pneumonia and, in some cases, death. The risk factors for poor outcomes have not been described well in a South Indian population.

Objective: We aimed to assess the incidence of dysphagia and subsequent pneumonia and mortality in a cohort of stroke patients.

Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021.

Importance: Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments. Nevertheless, epidemiological studies often cluster SAH with other stroke types leaving its distinct burden estimates obscure.

Objective: To estimate the worldwide burden of SAH.

Transcutaneous electric nerve stimulation in restless leg syndrome with cirrhosis: a pilot study.

Background: The study aimed to evaluate the effect of transcutaneous electric nerve stimulation (TENS) on restless leg syndrome (RLS) severity, sleep, quality of life, anxiety, and depression in liver cirrhosis patients.

Research Design And Methods: This was single-arm, open label, pilot study. Cirrhosis patients with RLS were evaluated with International RLS Score (IRLSS, scored 0-40 for severity) at baseline and 1, 2, 4, 6 weeks.

Hepatic encephalopathy in cirrhosis: therapies and developments.

Hepatic encephalopathy (HE) is a frequent decompensation in patients with cirrhosis, which significantly affects morbidity and mortality. Ammonia is a major neurotoxin implicated in the pathogenesis, progression, and severity of HE, and various organs including the gut, muscle, kidney, and brain are involved in its metabolism. Therefore, therapeutic management involves reducing ammonia production and increasing its elimination from the blood and the brain.

Evaluation and refinement of zinc management options for field-specific nutrient management in eastern India.

In eastern India, zinc (Zn) has emerged as the most critical micronutrient impacting the yield of rice. Experiments were conducted for 2 years during the Rabi and Kharif rice seasons at 339 on-farm locations in five districts and four agroclimatic zones of Odisha state in eastern India to study the management of Zn in rice nurseries and the transplanted crop. At each location, five treatment plots were established in which nitrogen (N), phosphorus (P) and potassium (K) were applied to rice following site-specific nutrient management as guided by Rice Crop Manager (RCM), a web-based tool.

Comparison of microbial diversity and community structure in soils managed with organic and chemical fertilization strategies using amplicon sequencing of 16 s and ITS regions.

Soil microbial species diversity and distribution of microbial communities are vital for soil and crop health, nutrient cycling, availability, and subsequent plant growth. These soil dynamics are highly influenced and altered by various soil management practices, inputs, and agricultural techniques. In the present study, the effects of chemical and organic management practices on soil microbial diversity and community structure were examined and compared using amplicon sequencing of the 16S and ITS regions.

Acute-on-chronic liver failure (ACLF): the 'Kyoto Consensus'-steps from Asia.

Acute-on-chronic liver failure (ACLF) is a condition associated with high mortality in the absence of liver transplantation. There have been various definitions proposed worldwide. The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set in 2004 on ACLF was published in 2009, and the "APASL ACLF Research Consortium (AARC)" was formed in 2012.

Innovative determination of phytohormones in .

Introduction: Aloe vera is widely known for its therapeutic properties, but concerns regarding the levels of phytohormones and their potential impact on human health highlight the need for advanced analytical techniques. This study aims to develop and validate a sensitive method for the determination of six key phytohormones in Aloe vera using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Methods: A validated LC-MS/MS method was optimized for the determination and quantification of six phytohormones in Aloe vera: Abscisic Acid (ABA), Salicylic Acid (SA), Indole-3-Acetic Acid (I3AA), Gibberellic Acid (GA), 6-Benzylaminopurine (6BAP), and Isopentenyladenine (ISA).

Impact of different farming scenarios on key soil sustainability indicators driving soil carbon and system productivity of rice-based cropping systems.

This research explores the relationships among soil characteristics, carbon dynamics, and soil biome in rice-based cropping systems across four farming scenarios: conventional farming, organic farming with conventional tillage, integrated nutrient management, and conservation agriculture with zero tillage. Conducted at the International Rice Research Institute, India (2020-2022), the study analyzed physical, chemical, and biological soil parameters. The findings reveal significant effects of farming scenarios on soil organic carbon (SOC), available nitrogen (N), phosphorus (P), and potassium (K), with no notable impact on bulk density, pH, electrical conductivity, or water-holding capacity.

Seroprotection achieved with standard four-dose schedule of hepatitis B vaccine in people with chronic kidney disease: A real-life data.

Background And Objectives: Hepatitis B virus (HBV) infection is common in people with chronic kidney diseases (CKD). The guidelines recommend four doses, 2.0 mL each, of HBV vaccine, given at zero, one, two and six months in these patients.

Granulocyte Colony-Stimulating Factor Improves Prednisolone Responsiveness and 90-Day Survival in Steroid-Eligible Severe Alcohol-Associated Hepatitis: The GPreAH Study a Randomized Trial.

Introduction: Severe alcohol-associated hepatitis (SAH) carries high 1-month mortality. Corticosteroids provide a modest 28-day but not 90-day survival benefit, due to development of infections and organ failures. Granulocyte colony-stimulating factor (GCSF) has shown promise in patients with SAH by its immunomodulatory and regenerative capabilities.

Echocardiographic predictors and associated outcomes of multiple vegetations in infective endocarditis: A pilot study.

Background: Infective endocarditis (IE) is a life-threatening infection with an annual mortality of 40%. Embolic events reported in up to 80% of patients. Vegetations of > 10 mm size are associated with increased embolic events and poor prognosis.

Paradigm shift in transfusion practices during early COVID-19 pandemic: A single center retrospective study.

Background: The advent of coronavirus disease 2019 (COVID-19) unveiled the worst national blood crisis that the United States had witnessed in over a decade. With the pandemic influencing the different stages of the acquisition of blood products outside the hospital setting, we aimed to explore the possible barriers contributing to the shortage of blood products within the medical community.

Aim: To assess the adherence to restrictive blood transfusion practices for patients in the COVID era and pre-COVID era.

High-quality genome assembly and annotation of five bacteria isolated from the Abu Dhabi sabkha-shore region.

Objectives: Sabkhas represent polyextreme environments characterized by elevated salinity levels, intense ultraviolet (UV) radiation exposure, and extreme temperature fluctuations. In this study, we present the complete genomes of five bacterial isolates isolated from the sabkha-shore region and investigate their genomic organization and gene annotations. A better understanding of the bacterial genomic organization and genetic adaptations of these bacteria holds promise for engineering microbes with tailored functionalities for diverse industrial and agricultural applications, including bioremediation and promotion of plant growth under salinity stress conditions.

Natural resource-derived NiO nanoparticles via aloe vera for high-performance symmetric supercapacitor.

This investigation reported a one-step green synthesis of nickel oxide nanoparticles (NiO NPs) using aloe vera leaves extract solution for their application in a supercapacitor. This method used aloe vera leaves as a reducing agent, which is very simple and cost-effective. The synthesized NPs were thoroughly characterized using various techniques.

Sustainability, performance, and production perspectives of waste-derived functional carbon nanomaterials towards a sustainable environment: A review.

The survival of humanity is severely threatened by the massive accumulation of waste in the ecosystem. One plausible solution for the management and upcycling of waste is conversing waste at the molecular level and deriving carbon-based nanomaterial. The field of carbon nanomaterials with distinctive properties, such as exceptionally large surface areas, good thermal and chemical stability, and improved propagation of charge carriers, remains a significant area of research.