Publications by authors named "Shivesh Singh"

Dengue, a vector-borne acute febrile illness caused by members of the Flavivirus genus, has dramatically increased its occurrence worldwide. Neurological complications of dengue range from 2.63 to 40%, and subarachnoid hemorrhage is a rare, but significant manifestation.

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  • Sheehan syndrome happens when a part of the pituitary gland gets damaged after a woman has heavy bleeding after giving birth.
  • Symptoms can include not being able to produce milk and missing periods, and sometimes it can become serious if there are other health issues, like with adrenal glands.
  • In a case study, a 45-year-old woman got very sick with a dengue infection and was diagnosed with Sheehan syndrome, which led to her needing hormone treatment to feel better.
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At present, food security is a matter of debate of global magnitude and fulfilling the feeding requirement of > 8 billion human populations by 2030 is one of the major concerns of the globe. Aquaculture plays a significant role to meet the global food requirement. Shrimp species such as Litopenaeus vannamei, Penaeus monodon, and Macrobrachium rosenbergii are among the most popular food commodities worldwide.

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Background: Dental implant surgery despite its growing popularity poses several challenges like include tissue inflammation, pain discomfort and tissue injury.

Objective: To evaluate the effect of ozone therapy on inflammation, pain and wound healing after implant surgery.

Methods: A clinical study was conducted on 60 systematically healthy patients- 30 patients treated with ozone (Experimental group) and 30 patients without ozone treatment (control group).

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Host-parasite relationships can be best understood at the level of protein-protein interaction between host and pathogen. Such interactions are instrumental in understanding the important stages of life cycle of pathogen such as adsorption of the pathogen on host surface followed by effective entry of pathogen into the host body, movement of the pathogen across the host cytoplasm to reach the host nucleus and replication of the pathogen within the host. White Spot Disease (WSD) is a havoc for shrimps and till date no effective treatment is available against the disease.

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  • Carcinoma cervix is a preventable disease caused primarily by high-risk strains of Human Papillomavirus (HPV) 16 and 18, leading researchers to investigate a new detection method using Nested Multiplex Polymerase Chain Reaction (NMPCR).
  • In a study with 119 female participants, HPV 16/18 was detected in 33.6% of cases, showing varying positivity rates in different cervical lesion stages, such as 80% in Squamous Cell Carcinoma and 66.7% in high-grade lesions.
  • The findings suggest that NMPCR could be a valuable screening tool for detecting HPV 16/18 in cervical samples, particularly in conjunction with traditional Papanic
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White spot disease is a devastating disease of shrimp Penaeus monodon in which the shrimp receptor protein PmRab7 interacts with viral envelop protein VP28 to form PmRab7-VP28 complex, which causes initiation of the disease. The molecular mechanism implicated in the disease, the dynamic behavior of proteins as well as interaction between both the biological counterparts that crafts a micro-environment feasible for entry of virus into the shrimp is still unknown. In the present study, we applied molecular modeling (MM), molecular dynamics (MD) and docking to compute surface mapping of infective amino acid residues between interacting proteins.

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Parachute tricuspid valve is a rare anomaly usually reported in small children. This report describes transthoracic and trans-oesophageal echocardiographic (TEE) features of parachute mitral valve in an adult patient.

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