The temporal change in heat-related mortality in relation to the Heat Health Action Plans in the five major cities of Australia.

Heat-Health Action Plans (HHAPs) are essential public health interventions to reduce heat-related mortality and morbidity, yet how heat-related health risks have changed following their implementation remains scarce. This study aimed to examine the temporal changes in heat-related mortality in relation to the implementation of the HHAPs across five major cities of Australia, including Melbourne, Sydney, Brisbane, Adelaide, and Perth. Daily mortality and temperature data from 1999-2019 were analysed using distributed lag non-linear models to compare the heat-related mortality attributable fractions (AF%) between pre- and post-HHAP periods.

Dual Detection of Glucose Using Commercial Potassium Permanganate and Glucose Oxidase: Colorimetric and Absorbance-Based Approaches.

Accurate and accessible glucose detection is essential for clinical diagnostics, point-of-care testing, food safety, and biosensing applications. In this study, we present a simple, scalable, and dual-mode glucose sensor that integrates commercial potassium permanganate (KMnO) with glucose oxidase to enable sensitive and selective detection in the clinically critical range of 1-5 mM. Leveraging the strong oxidative power and distinct optical characteristics of KMnO, the sensor operates via both absorbance measurement at 400 nm and visual colorimetric analysis, displaying a clear color change from purple to pink and yellow upon reaction with glucose.

Outcomes of Allogenic Umbilical Cord Mesenchymal Stem Cell infusion for Liver Cirrhosis due to Biliary Atresia after Kasai Operation.

Background And Aim: Although Kasai surgery has saved many patients with biliary atresia, the long-term survival rate remains low. Recently, cell therapy has been explored as a potential strategy to improve post-surgical survival. This study aims to evaluate the safety and outcomes of allogeneic umbilical cord mesenchymal stem cell (UC-MSC) infusion in management of liver cirrhosis due to Biliary Atresia after Kasai Operation.

Transitions and patterns in concurrent use of cigarettes and electronic cigarettes: An intensive longitudinal study of adults who smoke cigarettes and recently initiated e-cigarette use.

Background: There is a knowledge gap in the short- and long-term tobacco use patterns of adults who smoke cigarettes and initiate use of electronic cigarettes. This longitudinal study describes concurrent use transitions following e-cigarette initiation among adults who smoked cigarettes.

Methods: From December 2020-October 2021, US adults who smoked cigarettes and recently (re-)initiated e-cigarette use within the past month (N = 303) were recruited nationally for a one-year online study consisting of weekly surveys for three months followed by three quarterly surveys.

Case Report: A Bilateral Synchronous Primary Non-Small Cell Lung Cancer Patient With Two Different EGFR Mutations.

Background: Non-small cell lung cancer (NSCLC) represents the majority of lung cancer cases, with epidermal growth factor receptor (EGFR) mutations playing a crucial role in disease prognosis and treatment. Around half of Asian patients with NSCLC, particularly non-smoking women, have EGFR mutations. These patients with NSCLC typically exhibit a single EGFR mutation in exon 18, 19, 20, or 21.

A 19F Blake Drain versus a 28F Conventional Drain Following Video-Assisted Thoracoscopic Esophagectomy for Esophageal Cancer: A Comparative Retrospective Study.

Background: Pleural drainage is essential for preventing and managing respiratory complications after video-assisted thoracoscopic esophagectomy (VATE). Conventional large-bore drains often cause significant pain. Small-bore drains (e.

Long-term patency and complications of single orifice hepatic venous outflow reconstruction in right lobe graft living donor liver transplantation: A Vietnamese center experience.

Backgrounds/aims: Reconstruction of hepatic venous outflow is crucial in living donor liver transplantation (LDLT) to prevent graft congestion. This study evaluated the feasibility, long-term patency, complications, and survival rates of single-orifice hepatic venous outflow reconstruction using right lobe grafts.

Methods: A prospective study was conducted involving 52 patients who underwent LDLT with right lobe grafts at 108 Military Central Hospital, Vietnam, from January 2019 to December 2020, with follow-up extending until December 2024.

Single-incision laparoscopic endorectal pull-through for Hirschsprung's disease in neonates: A prospective study on medium-term outcomes.

Background: Single-incision laparoscopic endorectal pull-through (SILEP) has gained attention as a minimally invasive alternative to conventional laparoscopic surgery (CLS) for Hirschsprung's disease (HD). While SILEP offers superior cosmetic outcomes and reduced postoperative morbidity, its feasibility, safety, and functional outcomes in neonates remain underexplored. This study aimed to prospectively evaluate the outcomes of SILEP in neonates with HD.

Reduced graphene oxide-based absorbance biosensors for detecting Escherichia coli DNA.

Escherichia coli represents a significant concern for food safety, water quality, medical applications, and environmental health, necessitating effective detection methods. This study presents a reduced graphene oxide-based biosensor for the sensitive and specific detection of E. coli DNA.

Exploring Everyday Experiences of Adolescents Living With Asthma Through Bronfenbrenner's Ecological Systems Theory.

Aim: To explore Taiwanese adolescents' experiences with asthma.

Design: Exploratory qualitative study using semi-structured face-to-face interviews, framed within Bronfenbrenner's Ecological Systems Theory.

Methods: Data were collected until saturation was reached.

Discrepancies between supervisor self-evaluations and staff perceptions of leadership: a cross-sectional study in healthcare.

Background: Employees' perceptions of their supervisors' leadership influence their conduct and daily performance. These perceptions often conflict with leaders' self-assessments. Understanding this incongruency can help leaders improve their leadership skills.

Triple-Negative Breast Cancer Cells Activate Sensory Neurons via TRPV1 to Drive Nerve Outgrowth and Tumor Progression.

The tumor microenvironment in triple-negative breast cancer (TNBC) is characterized by increased sensory nerve density, which contributes to cancer progression by promoting migration and metastasis. However, the origin of tumor-innervating nerves and the mechanisms driving sensory innervation into tumors remain poorly understood. Using retrograde labeling techniques, we show that mammary tumors are associated with an increase in nerves originating from the dorsal root ganglia.

Wearable sensor data visualization for patient monitoring and management: a Cancer Wellness application in Vietnam.

This study incorporates Fitbit wearable sensor technology into a mobile application named Cancer Wellness Program (CWP) for patient monitoring. The objective of this study is to explore the experiences of healthcare providers in using the CWP application for managing symptoms of people with cancer and in delivering health education programs. : A qualitative study design with a purposive sampling approach was employed, using a structured, in-depth interview method to involve 15 healthcare workers.

"Sun brings all things": Sun and moon lore as biocultural knowledge on Aneityum island, Vanuatu.

Across the Pacific, traditional myths and contemporary narratives describe the origins, animacy, and importance to daily human activities of the Sun and Moon. In Vanuatu, Indigenous local knowledge systems interpret ways that the Sun and Moon interact with humans and plants to achieve productive and sustainable lifeways. In this ethnographic study, we explore how residents of Aneityum Island perceive and narrate the Sun and Moon's interactions with animals, humans, and plants.

Outcomes of Therapeutic Plasma Exchange Among Children With Autoimmune Encephalitis in Vietnam.

Autoimmune encephalitis is a group of inflammatory brain diseases causing neuropsychiatric symptoms, seizures, and memory problems. If untreated, autoimmune encephalitis can lead to serious complications and even death. Therapeutic plasma exchange may improve outcomes in severe or treatment-resistant cases.

Extracellular vesicle microRNA cargoes: candidates for diagnosis and targeted therapy of cutaneous wound healing.

Background: Non-healing wounds lead to tissue dysfunction, contributing to pathological conditions and compromising overall health. Recently, microRNAs have been shown to regulate diverse biological events, including cell migration, proliferation, angiogenesis, scar formation, and wound closure. Interestingly, cells selectively sort microRNAs into extracellular vesicles, which can be up-taken by cells to regulate the healing process.

Implementation of the International Code of Marketing of Breast-milk Substitutes and maternity protection: correlations with commercial milk formula consumption in East Asia and the Pacific.

Objective: The rise of commercial milk formulas (CMF) consumption by infants and young children raises concerns about their health, development, and survival. Implementing the International Code of Marketing of Breast-milk Substitutes (the Code) and maternity protection policies are two of seven critical policy actions to protect breastfeeding. This study explores the implementation of the Code, maternity protection policies, and CMF consumption in 11 countries in the East Asia Pacific (EAP) region and determines whether there are any correlations.

Characterization and prediction of hematotoxicity in pediatric patients receiving tisagenlecuecel.

Hematotoxicity is the most frequent severe toxicity following chimeric antigen receptor (CAR) T therapy. However, limited data exist on risk factors and outcomes for hematotoxicity for children and young adults (CAYA) with B-acute lymphoblastic leukemia (B-ALL) treated with tisagenlecleucel. We conducted a multi-institutional study involving 326 CAYA, with 144 evaluable in an initial training cohort and 141 evaluable in a validation cohort, through the Pediatric Real World CAR Consortium to characterize the incidence and outcomes of prolonged severe neutropenia (PSN) and to develop a predictive risk score for PSN, tailored for use in this population.

Thyroid nodule rupture and hyperthyroidism following radiofrequency ablation: A case report.

Radiofrequency ablation (RFA) plays a crucial role in the treatment of benign thyroid nodules by offering a minimally invasive alternative to surgical interventions. Nodule rupture is an uncommon complication of RFA. We present a case of nodule rupture and hyperthyroidism after RFA 41 days in a 45-year-old male patient.

A rare unusual location of neuroblastoma in theanterior-middle mediastinum in infant: A case report and literature review.

Neuroblastoma is a common tumor in children; however, its occurrence in the mediastinum - particularly in the anterior-middle mediastinum - is rare. Early diagnosis is crucial to initiate timely treatment and prevent disease progression. Surgery and chemotherapy are the standard treatments for neuroblastoma.

Intensive luteal phase support in hormone replacement and modified natural cycle frozen embryo transfers in ovulatory patients: A propensity score-matched study.

Background: The optimal endometrial preparation protocol for frozen embryo transfer (FET) remains controversial, with different cycle regimens and luteal phase support strategies across studies yielding conflicting results. This study aimed to compare the pregnancy outcomes of modified natural cycles (mNC) versus hormone replacement therapy (HRT) cycles, both with intensive luteal support using vaginal micronized progesterone and oral dydrogesterone.

Methods: This retrospective cohort study included 2365 FET cycles (1892 HRT and 473 mNC) in ovulatory women.

Enhanced sodium-ion intercalation and migration in boron/carbon-doped WS/graphene bilayers: insights from electronic structure calculations.

Heterostructures composed of graphene (G) and WS have recently been proposed as a promising new two-dimensional carbon allotrope for an anode material in sodium-ion batteries. Actively controlling material defects by substituting sulfur (S) atoms on the surface of WS with alternative dopants is anticipated to be a potential strategy for enhancing the electrochemical performance of WS/G heterostructures. Here, we employ first-principles density functional theory (DFT) calculations to systematically investigate the impact of boron (B) and carbon (C) doping on the sodium intercalation and diffusion mechanisms within the heterostructures.

A non-enzymatic doxycycline absorbance sensor based on manganese-doped zinc sulfide nanoparticles coated with chitosan.

The need for doxycycline detection is urgent because it is a vital antibiotic extensively utilized to combat bacterial diseases in humans and animals, and it is now at the forefront of the global battle against antibiotic resistance. Our research introduces an absorbance biosensor that employs chitosan-capped ZnS nanoparticles doped with manganese without an enzyme to address this critical need. Our study highlights the sensor's robust performance with nearly 100% recovery and stability over time to detect doxycycline from 0 to 72.

Perceptions of Modernized Anatomy Teaching Tools and Methods: A Mixed Method Study Among Medical, Nursing Students and Faculty.

Anatomy education is fundamental for medical and nursing students. There is a growing shift toward modern tools such as 3D applications, virtual dissection tables, and plastinated cadavers. This mixed-methods study at VinUniversity explored perceptions of these innovations.