Chitosan nanoparticles-encapsulated cannabis extracts and their antimicrobial potential against skin pathogens.

Cannabis compounds are well-known for their therapeutic applications in the treatment of various health issues. These substances, mainly cannabinoids, are known for their antimicrobial properties and ability to interact with various cells through endocannabinoid receptors. However, the limitations of cannabis extract, particularly its viscosity, stickiness, and low bioavailability when applied topically, limit its use in dermatology.

Patient and Physician Perspectives on Cardiovascular Risk: A Multicenter Survey of Communication Gaps Among Hospitalized Patients in Spain.

Background: Effective risk communication is essential in managing cardiovascular disease, the leading cause of global mortality. Clear communication between patients and physicians supports informed decision-making, yet comprehension gaps persist. We aimed to assess the quality of risk communication during hospital admissions for cardiovascular events, from patient and physician perspectives, and identify discrepancies in risk perception and associated factors.

Engineering the crystal structure and band gap of SrTeO: inducing bonding changes and metallization through compression.

The impact of external pressure on the characteristics of SrTeO has been thoroughly examined using density-functional theory calculations up to 100 GPa. It has been predicted that SrTeO undergoes three phase transitions in the pressure range covered by this study. A first transition occurs at 2.

Strategies for Enhancing Resilience in Horticultural Crops Against Combined Abiotic Stresses.

Horticultural crops are increasingly exposed to simultaneous abiotic stresses such as drought, salinity, and temperature extremes, which often exacerbate each other's effects, leading to severe yield and quality losses. Addressing these multifaceted challenges necessitates the development and application of integrated and innovative strategies. This review highlights recent advancements in methodologies to enhance the resilience of horticultural crops against combined abiotic stresses.

Description of chromatographic performance in reversed-phase liquid chromatography based on a generalised model. Part I: Column characterisation.

Liquid chromatography has advanced considerably since its introduction in the 1970s, with reversed-phase liquid chromatography (RPLC) becoming the dominant technique for separating non-volatile molecules. A key strategy for optimising separation conditions is the modelling of chromatographic retention from experimental data. Traditionally, this is achieved by fitting model parameters for each solute, resulting in individual solute models (ISMs).

Metabolic and microbial responses of Ceratitis capitata to essential oil-based nano-emulsions: Implications for pest management.

Essential oils (EOs) are a promising alternative to conventional pesticides, but some challenges like high volatility, poor water solubility, and rapid degradation limit their use in Integrated Pest Management (IPM). To overcome these limitations, this study aimed to develop garlic, eucalyptus, and clove EO-based nano-emulsions (EO-NEs) in a bait treatment format through the high-pressure microfluidization technique and investigated the biological activities against Ceratitis capitata. In addition, the adverse effects of the most promising nano-emulsion were evaluated towards a non-target parasitoid Anagaspis daci.

Use of Electrolysed Water as Disinfection Technology in Front of Various Microorganisms and SARS-COV-2.

The global emergence of SARS-CoV-2 has highlighted the urgent need for effective disinfection strategies to mitigate virus transmission. Electrolyzed water (EW), an eco-friendly and cost-effective biocidal agent, has garnered attention for its broad-spectrum antimicrobial activity. This study evaluates the virucidal, bactericidal, and fungicidal capacities of EW with diverse pH, with a focus on its effectiveness against SARS-CoV-2 and other pathogens.

Valorization of metabolite-enriched carbohydrates from Theobroma biomass via ultrasound-assisted alkaline extraction.

Polysaccharides, widely used in food, pharmaceutical and industrial sectors, are abundant in Theobroma species pod husk waste (T. cacao, T. grandiflorum and T.

CO Adsorbates Induced Framework-Associated Low-Valence Co Sites in Co-ZSM-5 for Ethane Dehydrogenation.

The dynamic structural evolution of heterogeneous catalysts is a ubiquitous phenomenon that has attracted a lot of interest. Catalyst reconstruction can occur after appropriate pretreatment, resulting in more efficient active catalysts, which is an attractive but challenging issue. Here, we reveal a CO activation strategy that controls the microenvironment of the Co sites in the high-silica Co-ZSM-5 catalyst (denoted as 0.

Physicochemical, Nutritional and Functional Properties of Neltuma affinis Pod Powders: a Novel Ingredient for Food Applications.

The pods of Neltuma species have been traditionally used as nutrient-rich sources of food ingredients. However, Neltuma affinis, a native species of South America, remains understudied. This work aimed to produce and characterize powders from different pod fractions (specifically, the endocarp-seeds (ESF) and epicarp-mesocarp (EMF) fractions) by dry grinding, evaluating their physicochemical, nutritional, functional, and cytotoxic properties.

A systematic review of health promoting effects of consumption of whey-based fermented products on adults.

Introduction: Fermented whey-based products show significant potential as functional foods, owing to their rich nutritional profile and the generation of bioactive compounds during fermentation. This systematic narrative review evaluates the health effects of fermented-whey consumption based on evidence from human studies in adults.

Methods: A systematic literature search was conducted using electronic databases including, PubMed, Scopus, and Cochrane Library for studies published between 1.

Improving the thermoelectric power factor of PEDOT:PSS with 4,4'-bipyridine and LiBF .

Background: Thermoelectric (TE) materials can directly convert heat into electricity, which is beneficial for energy sustainability. Organic conducting polymers are TE materials that have drawn significant attention owing to different favorable properties, such as good processability, availability, flexibility, and intrinsically low thermal conductivity. Among the organic TEs, poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is the most extensively investigated material because of its stability and high electrical conductivity.

Generative Artificial Intelligence and the Craft of Qualitative Health Research: Observations From a Techno-Negative Stance.

In this essay, I offer my take on contemporary matters relevant to the existing, emerging, and imagined intersections between qualitative health research (QHR) and generative artificial intelligence (GenAI). The essay's central argument is that the increasing reliance on GenAI in QHR is eroding scholarly craftspersonship and should be challenged. In order to present and justify this argument, I posit five coordinated observations: The growing body of literature on using GenAI in qualitative research is reducing qualitative research to coding and pattern recognition; the turn to GenAI disincentivizes reading and stultifies qualitative health researchers; the infatuation with GenAI amplifies the process of McDonaldization of QHR; the time that GenAI saves us isn't being used to become better researchers; and our tendency to humanize GenAI may dehumanise us, whereas craftspersonship is a state of being human.

Organ-level gene regulatory networks inferred from transcriptomic data reveal context-specific regulation and highlight novel regulators of ripening and ABA-mediated responses in tomato.

Tomato (Solanum lycopersicum) is a globally important crop, yet the gene regulatory networks (GRNs) controlling gene expression remain poorly understood. In this study, we constructed GRNs for roots, leaves, flowers, fruits, and seeds by inferring transcription factor (TF)-target interactions from over 10,000 RNA-seq libraries using the GENIE3 algorithm. We refined these networks with gene co-expression data and computational predictions of TF binding sites.

Defining non-invasive criteria for indicating drug therapy in metabolic-associated steatotic liver disease in clinical practice.

Background: &Aim:Resmetirom is the first FDA-approved drug for metabolic-associated liver disease(MASLD) in F2-F3 patients with steatohepatitis. Non-invasive criteria have been proposed for initiating treatment; however, these have not been validated in clinical practice. We validated the proposed criteria and established new guidelines for initiating resmetirom treatment in clinical practice.

Current Situation of Solid Organ Transplantation from HIV-Positive Donors to HIV-Positive Recipients in Europe. The Spanish Perspective.

Objectives: There is limited information on the use of organs from HIV-positive donors (HIV D+) for HIV-positive recipients (HIV R+) in Europe. In some countries the use of HIV D+ organs is prohibited by law. This study aimed to assess the attitudes of Spanish kidney and liver transplant (KT/LT) teams towards HIV D+/R+ KT/LT through a nationwide survey, and to evaluate the current situation across Europe regarding legislation and reported cases.

Extra-Virgin Olive Oil and Additional Cardiovascular Outcomes in the PREDIMED Trial: An Outcome-Wide Perspective.

Background And Aims: Olive oil, increasingly consumed in the U.S., has been inversely associated with cardiovascular disease (CVD) risk.

Description of chromatographic performance in reversed-phase liquid chromatography based on a generalised model. Part II: Prediction of serial-column coupling.

While reversed-phase liquid chromatography (RPLC) using C18 columns remains a cornerstone technique in analytical separations, its limited selectivity has driven the development of alternative stationary phases and advanced strategies, such as serial-column coupling, to expand chromatographic capabilities. This approach connects columns of different lengths and chemistries in series to create hybrid configurations that enhance separation performance. Beyond improving resolution, serial coupling can also reduce analysis times, particularly combined with modern zero-dead-volume connectors that minimise band broadening, which have renewed interest in this approach.

The effect of nursing training on dependence-related skin lesions: a quasi-experimental study.

Objective: To assess the effectiveness of ad hoc designed, mixed methodology training on the prevention, classification and categorisation of dependence-related skin lesions (DRSL) among nursing professionals at a public general hospital in Spain.

Method: A quasi-experimental study comprising a single group with 'pre-test' and 'post-test' measurements and measurements at 15 months involving nursing professionals from two hospitalisation units. The data were analysed considering the scores obtained in the measuring instrument, applied before, after and 15 months subsequent to a five-week blended training programme.

Age-related differences in cardiogenic shock secondary to Takotsubo syndrome.

Background: Age-related differences in Takotsubo Syndrome (TTS) have been described, but there is limited information regarding TTS patients who develop cardiogenic shock (CS).

Methods And Results: We analysed data from 408 CS-TTS patients in the RETAKO registry. Patients were stratified into three age groups: ≤50 years (9%), 51-74 years (48%), and ≥75 years (43%).

Unveiling the Interaction of Bowl-Shaped Polydopamine on Ti40Zr for Corrosion Resistance and Augmented Biomineralization Capacity.

The surface chemistry of Ti40Zr alloys plays a significant role in the formation of the bowl-shaped morphology of polydopamine (PDA). The bowl-shaped PDA morphology formation mechanism on the metal surface and its potential application in biomineralization and long-term stability as an implant material were investigated systematically. A novel nonsacrificial template-assisted bowl-shaped hollow capsule PDA formation was formed on alkali-treated Ti40Zr.

Latent resistance mechanisms of steel truss bridges after critical failures.

Steel truss bridges are constructed by connecting many different types of bars (components) to form a load-bearing structural system. Several disastrous collapses of this type of bridge have occurred as a result of initial component failure(s) propagating to the rest of the structure. Despite the prevalence and importance of these structures, it is still unclear why initial component failures propagate disproportionately in some bridges but barely affect functionality in others.

Radiomics Quality Score 2.0: towards radiomics readiness levels and clinical translation for personalized medicine.

Radiomics is a tool for medical imaging analysis that could have a relevant role in precision oncology by offering precise quantitative support for clinical decision-making. The Radiomics Quality Score (RQS) is a tool developed to assess the rigour of radiomics studies that has now been widely adopted by researchers. Although RQS version 1.

The evolutionary history of insect-associated xinmoviruses.

Viruses are ubiquitous biological entities that shape host evolution and ecosystem dynamics. Among them, negative-sense single-stranded RNA (-ssRNA) viruses form a diverse group that includes well-characterized vertebrate pathogens and an expanding repertoire of invertebrate-infecting viruses. Recent advances in high-throughput sequencing have revealed numerous insect-associated -ssRNA viruses, reshaping our understanding of their diversity, transmission, and ecological significance.

Carbon footprint assessment and sensitivity analysis of diagnostic colonoscopy.

Objectives: We aimed to perform a multifactorial carbon footprint assessment and sensitivity analysis of the colonoscopy procedure.

Design: One-week single-center prospective study with all outpatients' diagnostic colonoscopies was realized (n=66). A cradle-to-grave life cycle assessment (LCA) methodology evaluated all essential supplies (accessories from 1 to 15), endoscopic procedure (energy consumption, CO2 insufflation, bowel preparation, and sedation), staff and patients transport and waste management.