298 results match your criteria: "The Indiana University[Affiliation]"

Introduction: The Robotics Committee of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) conducted a study of surgeons' perspectives on robotic-assisted surgery (RAS) as compared to laparoscopic surgery (LS) in four domains: performance, requirements, challenges, and surgical care outcomes.

Methods: An exploratory sequential mixed-methods study was performed with a thematic analysis of surgeon interviews using the framework method, followed by an online survey of SAGES Robotics Committee members. Descriptive statistics, t-tests, and ANOVA were utilized for analysis.

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The development of a functional musculoskeletal system requires the combination of contractile muscle and extracellular matrix (ECM)-rich tendons that transmit muscle-generated force to bone. Despite the different embryologic origins, muscle and tendon integrate at the myotendinous junction (MTJ) to connect across this interface. While the cell-cell signaling factors have received considerable attention, how the ECM links these tissues remains unclear.

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Objective: The purpose of this study is to examine competency gaps among governmental public health workers with and without the Certified in Public Health (CPH) credential, specifically among the majority of the workforce without a formal public health degree.

Design: This cross-sectional study uses 2021 Public Health Workforce Interests and Needs Survey (PH WINS) data. Multivariate logistic regressions of reported skill gaps were performed while controlling for gender, age, race/ethnicity, public health degree attainment, role type, current employer, and tenure in public health practice.

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Recurrent vulvovaginal candidiasis associated with the use of a probiotic supplement.

IDCases

June 2025

The Indiana University School of Medicine, Department of Obstetrics & Gynecology, 550 University Blvd, Suite 2440, Indianapolis, IN 46202, United States.

Background: Recurrent vulvovaginal candidiasis (RVVC) is a common cause of morbidity in women with vulvovaginal complaints. species have been shown to cause vulvovaginal candidiasis in only 2 % - 6 % of RVVC cases. However, these infections are often resistant to typical medication regimens, resulting in treatment failure and recurrence.

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Clusters of Health-Related Social Needs Among Adult Primary Care Patients.

J Am Board Fam Med

May 2025

From the Indiana University Richard M. Fairbanks School of Public Health - Indianapolis, Regenstrief Institute, Center for Biomedical Informatics, Indianapolis, IN (JRV); Department of Psychology, Indiana University, Indianapolis, IN (WW); School of Social Work, University of Pittsburgh, Pittsburgh,

Introduction: Patients frequently report multiple health-related social needs (HRSNs) at the same time. This study aimed to identify clusters of co-occurring HRSNs in an adult primary care population.

Methods: We surveyed 1252 adult (>=18) primary care patients in Indianapolis, IN.

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Quantum Circuit and Mapping Algorithms for Wavepacket Dynamics: Case Study of Anharmonic Hydrogen Bonds in Protonated and Hydroxide Water Clusters.

J Chem Theory Comput

April 2025

Department of Chemistry, Department of Physics, and the Indiana University Quantum Science and Engineering Center (IU-QSEC), Indiana University, 800 E. Kirkwood Ave, Bloomington, Indiana 47405, United States.

The accurate computational study of wavepacket nuclear dynamics is considered to be a classically intractable problem, particularly with increasing dimensions. Here, we present two algorithms that, in conjunction with other methods developed by us, may result in one set of contributions for performing quantum nuclear dynamics in arbitrary dimensions. For one of the two algorithms discussed here, we present a direct map between the Born-Oppenheimer Hamiltonian describing the nuclear wavepacket time evolution and the control parameters of a spin-lattice Hamiltonian that describes the dynamics of qubit states in an ion-trap quantum computer.

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Using a Serious Game to Teach Central Line Care in Pediatric Critical Care Nursing.

Am J Nurs

February 2025

Mouhammad Yabrodi, Kamal Abulebda, and Riad Lutfi are associate professors and physicians at the Indiana University School of Medicine and Riley Hospital for Children, IU Health, Indianapolis, IN, where Mara E. Nitu is a professor and chief medical officer and Colin M. Rogerson is an assistant profe

Background: Central venous catheters (CVCs) are used in pediatric patients to deliver IV fluids, blood products, medications, and nutrients. Potential complications include central line infection, which carries a high risk of morbidity and mortality in this population. Pediatric critical care nurses play a crucial role in helping to reduce the risk of infection.

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Traditional guidance for intracranial aneurysm (IA) management is dichotomized by rupture status. Fundamental to the management of ruptured aneurysm is the detection and treatment of SAH, along with securing the aneurysm by the safest technique. On the other hand, unruptured aneurysms first require a careful assessment of their natural history versus treatment risk, including an imaging assessment of aneurysm size, location, and morphology, along with additional evidence-based risk factors such as smoking, hypertension, and family history.

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A Scoring System for Predicting Nonunion After Intramedullary Nailing of Femoral Shaft Fractures.

J Am Acad Orthop Surg Glob Res Rev

September 2024

From the Department of Orthopaedic Surgery (Dr. Kraus, Dr. Flores, Dr. Mullis, and Dr. Natoli), the Department of Biostatistics and Health Data Science (Dr. Slaven), Indiana University School of Medicine, Indianapolis, IN; the Indiana University School of Medicine, Indianapolis, IN (Dr. Sharma and D

Introduction: Femoral shaft nonunion negatively affects patient quality of life. Although multiple risk factors have been identified for femoral shaft nonunion after intramedullary nail (IMN) fixation, there is no quantitative model for predicting nonunion.

Study Description: The study is a retrospective cohort study of patients with femoral shaft fractures treated at two level one trauma centers who were followed to fracture union or nonunion.

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Need a Wood Lamp Alternative? Grab Your Smartphone.

Cutis

June 2024

Ruth Zagales is from the Indiana University School of Medicine, Indianapolis. Dr. Korman is from the Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus.

Article Synopsis
  • The Wood lamp is used to diagnose skin issues like vitiligo, erythrasma, and scabies.
  • It's often expensive and difficult to transport, and might not always be accessible.
  • Smartphone apps that mimic UV light can serve as a useful alternative when a Wood lamp isn't available.
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We provide an approach to sample rare events during classical ab initio molecular dynamics and quantum wavepacket dynamics. For classical AIMD, a set of fictitious degrees of freedom are introduced that may harmonically interact with the electronic and nuclear degrees of freedom to steer the dynamics in a conservative fashion toward energetically forbidden regions. A similar approach when introduced for quantum wavepacket dynamics has the effect of biasing the trajectory of the wavepacket centroid toward the regions of the potential surface that are difficult to sample.

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Objectives: The majority of pediatric patients in the United States (US) are evaluated and treated at general emergency departments. It is possible that discrepancies in length of emergency medicine (EM) residency training may allow for variable exposure to pediatric patients, critical resuscitations, and didactic events. The goal of this pilot study was to compare leadership skills of graduating EM residents from 3- to 4-year programs during simulated pediatric resuscitations using a previously validated leadership assessment tool, the Concise Assessment of Leader Management (CALM).

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Traumatic Hip Dislocation: Pediatric and Adult Evaluation and Management.

J Am Acad Orthop Surg

July 2024

From the Division of Orthopedic Trauma, Indiana University Methodist Hospital, Indianapolis, IN (Benedick, Lopas, Jang), the Division of Pediatric Orthopaedic Surgery, Indiana University - Riley Children's Hospital, Indianapolis, IN (Daley), and the Indiana University School of Medicine, Indianapoli

Traumatic hip dislocation of a native hip joint represents an orthopaedic emergency that should be treated promptly. Dislocations can be classified based on the associated injuries and the direction of dislocation. Expeditious evaluation, reduction, and management of associated injuries are required to optimize short and long-term function of the hip.

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Purpose: Entrustable professional activities (EPAs) are discrete clinical tasks that can be evaluated to help define readiness for independent practice in the health professions and are intended to increase trust in the dental graduate. EPAs provide a framework that bridges competencies to clinical practice. This report describes the work of the American Dental Education Association (ADEA) Compendium EPA Workgroup to develop a list of EPAs for dental education and supportive resources, including specifications and a glossary.

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Purpose: Cancer survivors commonly report cognitive declines after cancer therapy. Due to the complex etiology of cancer-related cognitive decline (CRCD), predicting who will be at risk of CRCD remains a clinical challenge. We developed a model to predict breast cancer survivors who would experience CRCD after systematic treatment.

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Body Mass Index and Mortality in Cardiogenic Shock.

ASAIO J

October 2024

Department of Cardiology, The CardioVascular Center, Tufts Medical Center, Boston, Massachusetts.

Article Synopsis
  • - The study examined how body mass index (BMI) affects mortality rates in patients experiencing cardiogenic shock (CS), using a large cohort from the Cardiogenic Shock Working Group registry.
  • - Results showed that a higher BMI correlated with increased mortality, particularly in those with heart failure-related mechanisms, while patients with normal weight had the lowest mortality rates.
  • - In the cohort, normal weight patients had a mortality rate of 29.0%, compared to 35.1% for obese and 36.7% for severely obese patients, though no significant differences were observed among BMI categories in cases related to acute myocardial infarction.
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Computer-aided drug design has advanced rapidly in recent years, and multiple instances of in silico designed molecules advancing to the clinic have demonstrated the contribution of this field to medicine. Properly designed and implemented platforms can drastically reduce drug development timelines and costs. While such efforts were initially focused primarily on target affinity/activity, it is now appreciated that other parameters are equally important in the successful development of a drug and its progression to the clinic, including pharmacokinetic properties as well as absorption, distribution, metabolic, excretion and toxicological (ADMET) properties.

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Importance: Providing recovery expectations for prolapse surgery is an important part of patient counseling and aids in patient-centered decision making.

Objectives: The purpose of this study was to determine if postoperative recovery from minimally invasive sacrocolpopexy (MISCP) is noninferior to that of native tissue repair.

Study Design: Recovery at 2 and 6 weeks was quantified using the Postdischarge Surgical Recovery 13 scale, where higher scores indicate greater patient-perceived recovery.

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Background And Purpose: Data analytics are increasingly important in health professions education to identify trends and inform organizational change in rapidly evolving environments. Unfortunately, limitations exist in data currently available to determine physical therapy (PT) academic excellence. It is imperative that the American Council of Academic Physical Therapy (ACAPT) be able to demonstrate data-informed progress in addressing the common challenges faced by Doctor of Physical Therapy programs.

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Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening.

N Engl J Med

March 2024

From the Indiana University School of Medicine, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, and Regenstrief Institute, Indianapolis (T.F.I.); Exact Sciences, Madison, WI (K.P., J.Z., Z.D.G., M.C.O., S.S., J.G., P.J.L.); Boston Biostatistics Research Foundation, Framingham,

Article Synopsis
  • A new multitarget stool DNA test was developed to enhance colorectal cancer screening by improving specificity and assessing both DNA markers and hemoglobin levels.
  • In a study involving over 20,000 adults aged 40 and older undergoing screening colonoscopy, the test’s sensitivity for colorectal cancer was found to be 93.9% and its specificity for identifying advanced neoplasia was 90.6%.
  • Compared to a standard fecal immunochemical test (FIT), the multitarget test showed significantly higher sensitivity for detecting colorectal cancer and advanced precancerous lesions, although the FIT had slightly better specificity for advanced neoplasia.
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In 2019, the revised Common Rule required informed consent documents for research to include a statement about whether clinically relevant research results would be returned to research participants. While there are national discussions regarding the return of results, these do not provide specific guidance about how institutional review boards (IRBs) should address this issue. Through a year-long process involving IRB staff and leadership, science and bioethics faculty members, community IRB members, and others, Indiana University's human research protection program created a framework that offers a clear categorization of types of results for researchers to consider returning, provides language for informed consent documents, and describes an active but intentionally limited role for the IRB.

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To assess COVID-19 and influenza vaccination rates across Indiana's 92 counties and identify county-level factors associated with vaccination. We analyzed county-level data on adult COVID-19 vaccination from the Indiana vaccine registry and 2021 adult influenza vaccination from the Centers for Disease Control and Prevention. We used multiple linear regression (MLR) to determine county-level predictors of vaccinations.

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Using Bibliometric Analysis to Map the Impact of a Simulation Program's Published Scholarly Works.

Simul Healthc

June 2024

From the Indiana University School of Medicine Interprofessional Simulation Center (D.L.R., M.D.N.), Bloomington, IN; Indiana University School of Medicine Department of Medicine (D.L.R.), Bloomington, IN; Indiana University School of Medicine (M.B.B., A.A.M.), Bloomington, IN; and Indiana Universit

Bibliometrics quantitatively evaluates the targeted literature sources and can help define research and scholarly publications' impact and demonstrate connections for authors, departments, or universities. This article presents a methodology for simulation programs to evaluate their influence in terms of both impact and scope of their published simulation-based healthcare scholarly output. Using the authors' home university and healthcare system as an example, the article outlines a methodology to map research and scholarly works networks within the systems, identify and map connections outside the system, and quantifiably score the overall impact of the simulation program's scholarly output using a common scoring metric, the h-index.

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