At least four groups of kratom consumers in the United States: latent-class analysis of motivations for kratom use.

Kratom is a plant with alkaloids acting at opioid, serotonergic, adrenergic, and other receptors. Consumers report numerous use motivations. To distinguish subgroups of kratom consumers by kratom-use motivations using latent-class analysis.

A Qualitative Study of First HIV Test Experiences Among Sexual and Gender Minority Adolescents.

Introduction: This qualitative study examined adolescents' first experiences with HIV testing.

Methods: Data were collected from April 2018 to October 2020 as part of an HIV prevention and sex education intervention; SGM adolescents ( = 175) answered open-ended questions regarding experiences with their first HIV test and advice for other adolescents seeking HIV testing. Data were analyzed through inductive content analysis.

Tailoring implementation strategies for the healthy actions and lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program: Lessons learned from a survey study.

Background: Healthy Actions and Lifestyles to Avoid Dementia Program (HALT-AD) or Hispanos y el ALTo a la Demencia is a recently-developed online educational platform to help individuals identify and modify their own dementia modifiable risk factors (MRF). In light of known challenges in recruiting and retaining diverse participants in research studies, there is a need to identify data-informed strategies that will contribute to effective outreach and tailored implementation of HALT-AD among its intended users of Hispanic and non-Hispanic midlife and older adults in the US.

Objectives: To identify factors (i.

Benefit Finding in Craniofacial Conditions: A Qualitative Analysis of Patient and Parent Perspectives.

Objective: Craniofacial conditions (CFCs) can be associated with adverse effects on quality of life (QoL). However, few studies have examined perceived benefits related to CFCs. This study described perceived benefits in an international sample of children and adolescents with CFCs and their parents.

Structure of subcortico-cortical tracts in middle-aged and older adults with autism spectrum disorder.

Middle-aged and older adults with autism spectrum disorder may be susceptible to accelerated neurobiological changes in striato- and thalamo-cortical tracts due to combined effects of typical aging and existing disparities present from early neurodevelopment. Using magnetic resonance imaging, we employed diffusion-weighted imaging and automated tract-segmentation to explore striato- and thalamo-cortical tract microstructure and volume differences between autistic (n = 29) and typical comparison (n = 33) adults (40 to 70 years old). Fractional anisotropy, mean diffusivity, and tract volumes were measured for 14 striato-cortical and 12 thalamo-cortical tract bundles.

Dulce Digital-Me: results of a randomized comparative trial of static versus adaptive digital interventions for Latine adults with diabetes.

Objective: To compare the effectiveness of a static, text-based diabetes education and support intervention (Dulce Digital, DD) versus a dynamic approach with personalized feedback and goal setting (Dulce Digital-Me, DD-Me) in improving diabetes outcomes.

Design And Methods: Comparative effectiveness trial in 310 Latine adults with poorly managed type 2 diabetes in a Federally Qualified Health Center in Southern California, randomized to DD, DD-Me-Auto (algorithm-driven text-based personalized feedback), or DD-Me-Tel (coach delivered personalized feedback). Changes in HbA1c (primary outcome), low-density lipoprotein-cholesterol, systolic blood pressure, and patient-reported outcomes were examined across 6 and 12 months, with the primary comparison being DD versus DD-Me (combined automated and telephonic).

Muscularity-oriented attitudes and behaviors among college-aged women: The role of sexual orientation.

While sexual minority (SM) status has been associated with poorer body image and greater eating pathology among men, findings are inconsistent among women. The lack of focus on muscularity-oriented attitudes and behaviors among SM women may contribute to these mixed findings; thus, we examined these constructs within a large sample of SM and heterosexual women. Our sample included 1511 cisgender women (n= 1213 heterosexual, n= 298 SM).

Randomized controlled trial of computerized working memory training for Veterans with PTSD.

Posttraumatic stress disorder (PTSD) is a common psychiatric condition among Veterans that is associated with deficits across a range of neuropsychological domains including working memory. While gold-standard psychosocial treatments are highly effective, there still remains a high rate of individuals who do not engage with or fully benefit from them. Cognitive training targeting specific working memory deficits in PTSD presents an alternative treatment approach that has shown promise for reducing re-experiencing symptoms.

Altered value-based decision-making in anorexia nervosa: A systematic review.

Alterations in decision-making are considered core to anorexia nervosa (AN) phenomenology and may maintain illness through maladaptive choice behavior. This systematic review (n = 77) aimed to extend prior reviews beyond standard neuropsychological batteries by incorporating novel value-based choice tasks and computational methods. We organize findings across key factors, including: 1) illness state, 2) developmental stage, and 3) AN subtype, and highlight available neuroimaging findings.

Gender Minority Stress, Resilience, and Psychological Distress: The Role of Resilience Among Transgender and Gender Diverse Youth.

Purpose: Gender minority (GM) stress, resulting from distal (i.e., external) and proximal (i.

Reward and Inhibitory Control as Mechanisms and Treatment Targets for Binge Eating Disorder.

Purpose Of Review: Recent research has highlighted alterations in reward and inhibitory control among individuals with binge eating disorder, identifying both constructs as potential targets for treatment. Treatments targeting reward and inhibitory control for binge eating disorder are emerging. This review aims to summarize the recent literature evaluating reward and inhibitory control in binge eating disorder compared to weight-matched controls using behavioral paradigms and neuroimaging.

A useful cognitive motor dual task paradigm in prodromal and manifest Huntington's disease.

Introduction: Individuals with Huntington's disease (HD) experience increased difficulty with balance throughout disease progression. Adding a simultaneous cognitive task to a balance assessment, referred to as a dual task (DT) paradigm, may have a deleterious effect on balance, which can be expressed in terms of a Dual Task Cost (DTC), relative to a single task (ST) condition. The aim of this study is to explore whether a cognitive-motor DT paradigm uncovers balance deficits in prodromal (Pro-HD) and manifest HD, compared to healthy adults (HA).

Self- and study partner-reported cognitive decline in older adults without dementia: The role of α-synuclein and amyloid biomarkers in the Alzheimer's Disease Neuroimaging Initiative.

Introduction: Subjective cognitive decline (SCD) may be an early marker of Alzheimer's disease (AD) pathology. Until recently, it was impossible to measure biomarkers specific for α-synuclein pathology; therefore, its association with subjective reports of cognitive decline is unknown.

Methods: Alzheimer's Disease Neuroimaging Initiative participants without dementia (n = 918) were classified as positive or negative for amyloid beta (Aβ+ or Aβ-) and α-synuclein (α-syn+ or α-syn-) biomarkers.

Socioeconomic status, reserve capacity, and depressive symptoms predict pain in Rheumatoid Arthritis: an examination of the reserve capacity model.

Background: Guided by the reserve capacity model, we evaluated the unique relationships between socioeconomic status (SES), reserve capacity (helplessness, self-efficacy, social support), and negative emotions on pain in patients with Rheumatoid Arthritis (RA).

Methods: The secondary analysis used baseline, cross-sectional data from 106 adults in a clinical trial comparing behavioral treatments for RA. Patients were eligible if they were ≥ 18 years old, met the ACR criteria for RA (determined by study rheumatologist), had stable disease and drug regimens for 3 months, and did not have a significant comorbid condition.

Sexual Abuse, Commercial Sexual Exploitation, and Cumulative Adversity Among Sexually Diverse and Non-Sexually Diverse Girls in the Juvenile Justice System.

Despite awareness about high rates of sexual abuse among girls in the juvenile justice system, little is known about the additional risk conferred upon sexually diverse (SD) youths, as well as the combined vulnerability of sexual abuse and commercial sexual exploitation of children (CSEC) - frequently a survival behavior amplifying disproportionate juvenile justice contact among SD and non-SD juvenile justice-involved (JJI) girls. In a sample of JJI-girls, we compared SD ( = 52) with non-SD ( = 46) JJI-girls on sexual victimization (e.g.

"Us big boys gotta find a way that works": A qualitative study of casual sexual experiences among larger-bodied, White and Latino sexual minority men.

Compared to their heterosexual counterparts, sexual minority men (SMM) are more likely to report that their own body image negatively impacts their sex lives, are more vulnerable to weight stigma, and more frequently experience size-based discrimination. Additionally, in comparison to heterosexual men, SMM report higher levels of anti-fat bias, both directed at themselves and intimate partners. Given this literature, we qualitatively examined how nine larger-bodied SMM (Mage = 37.

Altered Development of the Hurst Exponent in the Medial Prefrontal Cortex in Preschoolers With Autism.

Background: Atypical balance of excitation (E) and inhibition (I) in the brain is thought to contribute to the emergence and symptomatology of autism spectrum disorder (ASD). E/I ratio can be estimated from resting-state functional magnetic resonance imaging (fMRI) using the Hurst exponent, H. A recent study reported decreased ventromedial prefrontal cortex (vmPFC) H in male adults with ASD.

Coping, connection appraisal, and well-being during COVID-19 in the U.S., Japan, and Mexico.

Introduction: The COVID-19 pandemic has affected nearly every facet of life, constituting a "new normal" and prompting an ongoing collective psychological crisis. People's ways of coping with the pandemic and corresponding well-being are of particular research interest; however, these constructs have largely been examined using deductive quantitative approaches, deficit-based lenses, and mononational samples.

Methods: The current mixed-methods study used inductive-sequential (QUAL → QUAN) approaches to explore positive coping strategies (approach coping style and COVID-related connection appraisal) and well-being (loneliness, distress, and happiness) across individuals from the United States, Japan, and Mexico.