1,012 results match your criteria: "SRM Institute of Science and Technology SRMIST[Affiliation]"

Electrical performances of a biphenyl-derived amido Schiff base ligand L and its dinuclear Al(iii) complex (complex 1) were investigated in a metal-semiconductor (MS) junction. Electrical studies revealed that complex 1 significantly enhanced the electrical conductivity and improved the characteristics of a Schottky barrier diode (SBD). The - characteristics demonstrated that complexation of ligand L with Al(iii) ion increased the conductivity by two orders of magnitude (conductivity of L = 1.

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CDCG-UNet: Chaotic Optimization Assisted Brain Tumor Segmentation Based on Dilated Channel Gate Attention U-Net Model.

Neuroinformatics

January 2025

Department of Information Technology, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Ramapuram, Chennai, 600089, India.

Brain tumours are one of the most deadly and noticeable types of cancer, affecting both children and adults. One of the major drawbacks in brain tumour identification is the late diagnosis and high cost of brain tumour-detecting devices. Most existing approaches use ML algorithms to address problems, but they have drawbacks such as low accuracy, high loss, and high computing cost.

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In recent years, the design of various ultrasound responsive echogenic nanomaterials offers many advantages such as deep tissue penetration, high signal intensity, colloidal stability, biocompatibility and less expensive for ultrasound-based cancer cell imaging while providing the option to monitor the progress of tumor volume during the treatment. Further, the ability of nanomaterials to combine photo-thermal therapy (PTT) and chemotherapy has opened a new avenue in the development of cancer theranostics for synergistic cancer therapy. Herein, we report MoS nanoflowers (NFs) surface decorated with CuS nanorods (NRs) and folic acid-derived carbon dots (FACDs) using cystine-polyethyleneimine (PEI) linker for PTT-chemotherapy.

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Dentistry still faces difficulties in diagnosing oral precancer and cancer, especially when it comes to early phase changes or disease detection, evaluation, and treatment. In essence, oral lumenography is the process of identifying oral lesions using a chemiluminescent light source and a toluidine blue labeling system. Since neoplastic epithelial cells have a changed nuclear-cytoplasmic ratio, acetic acid dehydration brings out this nuclear density and gives the tissue an "acetowhite" look.

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With over two millennia of history, traditional Chinese acupuncture ranks among the most renowned forms of supplementary and other healthcare. The use of acupuncture releases endorphins and serotonin, two naturally occurring painkillers, into the nervous system and stimulates it. It also modifies how pain signals are processed and perceived.

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The Internet of Things (IoT)-based smart solutions have been developed to predict water quality and they are becoming an increasingly important means of providing efficient solutions through communication technologies. IoT systems are used for enabling connection between various devices based on the ability to gather and collect information. Furthermore, IoT systems are designed to address the environment and the automation industry.

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Facial bone fractures are a common occurrence in trauma cases, particularly in India where road traffic accidents contribute significantly. Over the past few years, artificial intelligence (AI) has become a potent instrument to help medical professionals diagnose and treat facial fractures. This study aims to perform a bibliometric analysis, that is, a quantitative and qualitative analysis, of publications focusing on the role of AI in detecting facial bone fractures.

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Luffa cylindrica (L.), is a medicinal plant aimed to investigate the efficacy of the alkaloid-rich fraction (ARF) extracted from L. cylindrica.

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Synergistic effects of fly ash and graphene oxide composites at high temperatures and prediction using ANN and RSM approach.

Sci Rep

January 2025

Department of Civil Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India.

Fly ash (FA) is a consequence of burning coal and is widely used in construction because of its pozzolanic qualities, which increase the strength and longevity of materials. Graphene oxide (GO) is a functionalized version of graphene with low electrical conductivity, high mechanical strength, and a large surface area. By examining the behavior of fly ash and GO composites at high temperatures, new materials with improved mechanical and functional qualities that are appropriate for a range of industrial uses can be created.

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Autism spectrum disorder (ASD) is the neuro-developmental disorder caused by various changes in the brain. It affects the life conditions with social interaction and communication. Most of the previous researches used the various techniques for the early detection to reduce the ASD, but it had been occurred several complications such as, time expenses, and low accessibility for diagnosis.

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Background: In India, approximately 3.5 million children are affected by Developmental Delay (DD), often stemming from preterm births. These delays contribute to neurological and motor development delays, placing a significant financial burden on families.

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In this study, five seagrass species Halodule uninervis, Thalassia hemprichii, Enhalus acoroides, Cymodocea serrulata, and Syringodium isoetifolium collected from the Mandapam coastal region of Rameswaram (Palk Bay region), Tamil Nadu, India, were selected to identify the antioxidant-rich proteins/peptides. The primary objective was to identify the proteins/peptides present in these seagrass filtrates extracted by using four different pH-based buffer extracts and to assess their antioxidant activity. Among the various buffer extracts, 0.

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Advanced thyroid nodule detection using ultrasonography image analysis and bilateral mean clustering strategies.

Comput Biol Med

March 2025

Department of Computing Technologies, School of Computing, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India. Electronic address:

This research work focuses on developing an advanced diagnostic method for thyroid nodules using ultrasonography images. The core idea revolves around the observation that the presence and amount of calcium flecks in thyroid nodules can indicate their severity, potentially leading to severe thyroid cancer. A novel technique, named Bilateral Mean Clustering Strategy (Bi-MCS), is proposed, combining the strengths of Fuzzy C mean and K-mean clustering approaches.

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"PolynetDWTCADx" is a sophisticated hybrid model that was developed to identify and distinguish colorectal cancer. In this study, the CKHK-22 dataset, comprising 24 classes, served as the introduction. The proposed method, which combines CNNs, DWTs, and SVMs, enhances the accuracy of feature extraction and classification.

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Role of miR-125b-5p in modulating placental SIRT7 expression and its implications for lipid metabolism in gestational diabetes.

J Reprod Immunol

February 2025

Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603 203, India. Electronic address:

Gestational diabetes is marked impaired glucose tolerance, poses various adverse outcomes including increased BMI and obesity. These outcomes results from excess lipid accumulation which is marked by elevated triglycerides. In GDM, placenta exhibits altered lipid metabolism, including reduced fatty acid oxidation and increased triglyceride accumulation.

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A Review on zerumbone and its semisynthetic Analogs: Synthesis and Implications in Medicinal chemistry.

Bioorg Chem

January 2025

Department of Chemistry, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, Tamil Nadu, India. Electronic address:

Natural products and their semisynthetic analogs have long standing history in generating and identifying lead and drug candidates for various therapeutic areas. Zerumbone 1, a unique 11 membered monocyclic sesquiterpene natural product is isolated from Zingiber zerumbet (L. Smith) and related species.

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Cervical cancer remains a significant health challenge in developing countries are high due to low HPV vaccination rates, delayed diagnosis, and restricted healthcare access. Metal nanomaterials, such as copper oxide (CuO) nanoparticles (NPs), have shown significant promise in cancer therapy due to their ability to induce apoptosis. 5-Fluorouracil (5-Fu) enhances the cytotoxic effect against cervical cancer, working synergistically with CuO NPs to maximize the therapeutic impact while potentially reducing the 5-Fu's systemic side effects.

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CesA proteins response to arsenic stress in rice involves structural and regulatory mechanisms, highlighting the role of BES1/BZR1 transcript levels under arsenate exposure and significant downregulation of BZR1 protein expression. Plants interact with several hazardous metalloids during their life cycle through root and soil connection. One such metalloid, is arsenic and its perilous impact on rice cultivation is a well-known threat.

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Nanomaterials impact in phytohormone signaling networks of plants - A critical review.

Plant Sci

March 2025

Interdisciplinary Institute of Indian System of Medicine, Directorate of Research, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, India. Electronic address:

Nanotechnology offers a transformative approach to augment plant growth and crop productivity under abiotic and biotic stress conditions. Nanomaterials interact with key phytohormones, triggering the synthesis of stress-associated metabolites, activating antioxidant defense mechanisms, and modulating gene expression networks that regulate diverse physiological, biochemical, and molecular processes within plant systems. This review critically examines the impact of nanoparticles on both conventional and genetically modified crops, focusing on their role in nutrient delivery systems and the modulation of plant cellular machinery.

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Atherosclerosis, a major cause of cardiovascular disease (CVD), involves plaque buildup in arteries driven by inflammation, endothelial dysfunction, and lipid metabolism disturbances. Current therapies aim to reduce cholesterol through statins and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors, prevent blood clots with antiplatelet drugs like aspirin, and control inflammation, alongside lifestyle modifications. However, these approaches often fall short due to patient non-compliance and residual risks.

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The twenty-first century presents a serious threat to public health due to the growth in antibiotic resistance among opportunistic bacteria, particularly within the ESKAPE group, which includes Enterobacter species with high morbidity, mortality, virulence, and nosocomial dissemination rates. Enterobacter species, especially Enterobacter cloacae, bacteria have developed resistance to multiple antibiotics through mechanisms, such as continuous production of AmpC beta-lactamase. In this study, a comprehensive bioinformatics approach was employed to analyze the genome of Enterobacter cloacae, utilizing sequence data from GenBank (ID: OW968328.

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Mycobacterium tuberculosis is a human pathogen that causes Tuberculosis (TB) disease. Researchers have reported the activity of traditional medicinal plants against human pathogens. However, antimycobacterial studies of medicinal plants against M.

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Recognizing the factors that cause dysfunction within a team is crucial for many teams. Growing studies have investigated the factors that affect college students' performance. This study focuses on the association between dysfunctional teams and student team performance (TP), with the mediating effect of students' attitudes towards team assessment.

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Background: Approximately 1 in 8 children under the age of 6 in Tamil Nadu are diagnosed with neurodevelopmental disorders (NDD), yet only a fraction of these children receives proper medical care. The unequal distribution of healthcare services is mainly due to the lack of accessibility, especially in rural areas, leading to a significant burden on caregivers. This research aims to alleviate caregiver burden and reduce disability in preschool children by establishing model clinics or specialized outreach centers in rural villages, supported by SRM Institute of Science and Technology under the Unnat Bharat Abhiyan Scheme.

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