Repetition blindness for emotion words: Exploring interactions between valence and arousal.

Emotional information is treated differently than any other type of information and has a powerful impact on many cognitive processes, including attention. The aim of this study was to investigate how valence and arousal impact how we process words in sentences, as well as examine two theories of emotion, categorical negativity theory and the arousal hypothesis. Categorical negativity theory suggests that the valence of a word is what truly influences how emotional information receives attention, while the arousal hypothesis posits that the arousal level of a word determines the amount of attention it receives.

Quantifying the effect of IMPEDE-FX packing rate and volume on pressure-normalized principal wall strain in an idealized 3D-printed aneurysm model.

Background: This study aimed to quantify the nonbiologic effects of Shape Memory IMPEDE-FX embolization plug deployment rate and packing volume on pressure-normalized wall strain ( /PP) of an idealized 3D-printed abdominal aortic aneurysm model.

Methods: An endograft was deployed into an abdominal aortic aneurysm model and connected to an industry-validated hemodynamic simulator. Plugs were deployed into the excluded sac to packing volumes of 100%, 200%, 300%, and 400% under two conditions: (1) sequential and (2) immediate deployment.

Showing the Bonds-A Subtle but Important Difference in Figure Design that May Alleviate Student Confusion about ATP Hydrolysis.

A misconception among biology students is that breaking bonds in adenosine triphosphate (ATP) releases energy. This misconception may be related to imprecise representations of chemical bonding in common diagrams of ATP hydrolysis. We interviewed 33 undergraduate students and randomly assigned them to interpret a figure of ATP hydrolysis that either emphasized bond breaking in the reactants or the formation of new bonds in the products.

Antibiotic treatment modulates -derived bacterial extracellular vesicle (BEV) production and their capacity to upregulate ICAM-1 in human endothelial cells.

Antibiotic treatment is often necessary to eliminate life-threatening bacterial infections. However, these treatments can alter production of bacterial extracellular vesicles (BEVs), which often contain pro-inflammatory biomolecules. In this study, we examined how the clinically-relevant antibiotics meropenem, tobramycin, and ciprofloxacin impacted BEV production from a urinary tract infection-associated strain (CFT073 [WAM2267]) and a meningitis-associated strain (K1 RS218).

Reorganization of bacterial community network structure in the eastern redback salamander (Plethodon cinereus) and its soil reservoir across a gradient of land use.

The eastern redback salamander Plethodon cinereus is prevalent in the urbanized northeastern USA and exhibits low susceptibility to the fungal pathogen Batrachochytrium dendrobatidis (Bd). Disease resistance is partially attributed to Bd-inhibitory microbes in the P. cinereus cutaneous microbiome, but less is known regarding the associations that structure these bacterial communities.

Tracking antibiotic resistance in the environment: whole-genome sequencing of seven bacteria from the soil and water.

Soil and water samples collected from the Rochester Institute of Technology campus were analyzed for antibiotic-resistant bacteria. Whole-genome sequencing and annotation were conducted on seven isolates that show a diverse range of resistance patterns, underscoring the urgent need for ongoing surveillance of antimicrobial resistance in the environment.

Transcription-templated assembly of the nucleolus in the embryo.

The nucleolus is a multicomponent structure made of RNA and proteins that serves as the site of ribosome biogenesis within the nucleus. It has been extensively studied as a prototype of a biomolecular condensate whose assembly is driven by phase separation. While the steady-state size of the nucleolus is quantitatively accounted for by the thermodynamics of phase separation, we show that experimental measurements of the assembly dynamics are inconsistent with a simple model of a phase-separating system relaxing to its equilibrium state.

Examining the influence of and a mentoring network on teaching philosophies and strategies.

The 2011 report () resulted from a national effort to rethink biology curriculum. outlines core concepts and core competencies for biology undergraduates and promotes evidence-based pedagogy, undergraduate research, and inclusive practices. However, it is unclear how much biology educators know about and what motivates educators' development of their teaching philosophy and practices.

PLM-DBPs: enhancing plant DNA-binding protein prediction by integrating sequence-based and structure-aware protein language models.

DNA-binding proteins (DBPs) play a crucial role in gene regulation, development, and environmental responses across plants, animals, and microorganisms. Existing DBP prediction methods are largely limited to sequence information, whether through handcrafted features or sequence-based protein language models (PLMs), overlooking structural cues critical to protein function. In addition, most existing tools are trained for general DBP predictions, which are often not accurate for plant-specific DBPs due to the unique structural and functional properties of plant proteins.

Oxygen transport in nanoporous SiN membrane compared to PDMS and polypropylene for microfluidic ECMO.

Extracorporeal Membrane Oxygenation (ECMO) serves as a crucial intervention for patients with severe pulmonary dysfunction by facilitating oxygenation and carbon dioxide removal. While traditional ECMO systems are effective, their large priming volumes and significant blood-contacting surface areas can lead to complications, particularly in neonates and pediatric patients. Microfluidic ECMO systems offer a promising alternative by miniaturizing the ECMO technology, reducing blood volume requirements, and minimizing device surface area to improve safety and efficiency.

Analytical Basal-State Model of the Glucose, Insulin, and C-Peptide Systems for Type 2 Diabetes.

We present a mechanistic mathematical model of the basal state for type 2 diabetes mellitus (T2DM) in an analytical form and illustrate its use for in silico basal-state and dynamic studies. At the core of the basal-state model is a quartic equation that expresses the basal plasma glucose concentration solely in terms of model parameters. This analytical model avoids a computationally intensive numerical solver and is illustrated by an investigation of how glucose-utilization parameters impact basal glucose, insulin, insulin-dependent utilization, and hepatic extraction, leveraging median parameter values of early-stage T2DM.

Effects of a Wearable Assistive Device on Postural Control and Stability During Symmetric and Asymmetric Intermittent Trunk Flexion Tasks.

Assistive devices, such as Exoskeletons (EXOs) can enhance endurance, but could inadvertently alter body mechanics, compromise balance, and elevate fall risk, particularly under fatigue. We evaluated effects of an EXO on postural stability during standing still and sustained trunk flexion tasks as users become fatigued during intermittently performed tasks. As trunk bending is common across many occupational/routine tasks, a repetitive 45° trunk flexion task was selected.

Modeling treatment of diabetic wounds with oxygen therapy and senolytic drug.

Diabetic wounds are common in patients with type 2 diabetes; they are ischemic and inflammatory, and difficult to heal without intervention. Hyperbaric oxygen therapy (HBOT) is a standard treatment, but its effectiveness is limited to a subset of the aging population. Senescent fibroblasts, a hallmark of aging, impair wound healing, and senolytic drugs, like quercetin (Q), which target senescent cells, may improve healing.

Gray hair influences perceived age and social perceptions.

Physical traits can influence how people are perceived and evaluated by others, often reflecting underlying qualities considered important for social interaction. Gray hair color is one such trait that can potentially alter social perceptions related to aging, but has rarely been investigated independently from other correlated physical characteristics. The aim of the current work is to investigate how gray hair independently influences important social evaluations including perceived age, attractiveness, social status, aggressiveness, and trustworthiness.

The Relationships Between Lifestyle Behaviors, Health Perceptions, and Psychosocial Outcomes of Metabolic Syndrome Severity.

Purpose: The prevalence of metabolic syndrome (MetS) continues to increase. The severity of MetS can be defined by the number of components or, more recently, a continuous MetS severity score (MetSSS). However, studies that examine lifestyle factors predictive of MetS severity, in general, are lacking.

Breaking boundaries: The effects of counter-stereotypical sources on ingroup persuasion and outgroup dissuasion.

People tend to align their policy attitudes with the stereotypical attitudes of their political group (e.g., conservatives supporting gun rights, liberals supporting abortion rights).

: a versatile model for studying archaeal biology.

Archaea, once thought limited to extreme environments, are now recognized as ubiquitous and fundamental players in global ecosystems. While morphologically similar to bacteria, they are a distinct domain of life and are evolutionarily closer to eukaryotes. The development of model archaeal systems has facilitated studies that have underscored unique physiological, biochemical, and genetic characteristics of archaea.

Health disparities among Deaf communities from Colombia: assessing communication, technology and healthcare access.

Introduction: Despite efforts to improve health equity, there is still limited knowledge about the number and characteristics of people with disabilities, particularly the Deaf community. Our aim is to use linguistically and culturally adapted research instruments to measure key health indicators and priorities within the Deaf community from a low- and middle-income country-Colombia, contributing to a better understanding of health inequities.

Methods: We used data from the Health Survey for Deaf (HSD) and National Quality of Life Survey (NQLS) from Colombia.

The Lysine Deprotonation Mechanism in a Ubiquitin Conjugating Enzyme.

Ubiquitination is a biochemical reaction in which a small protein, ubiquitin (Ub), is covalently linked to a lysine on a target protein. This type of post-translational modification can signal for protein degradation, DNA repair, or inflammation response. Ubiquitination is catalyzed by three families of enzymes: ubiquitin activating enzymes (E1), ubiquitin conjugating enzymes (E2), and ubiquitin ligases (E3).

Sketchy understandings: drawings reveal where students may need additional support to understand scale and abstraction in common representations of DNA.

Visual representations in molecular biology tend to follow a set of shared conventions for using certain shapes and symbols to convey information about the size and structure of nucleotides, genes, and chromosomes. Understanding how and why biologists use these conventions to represent DNA is a key part of visual literacy in molecular biology. Visual literacy, which is the ability to read and interpret visual representations, encompasses a set of skills that are necessary for biologists to effectively use models to communicate about molecular structures that cannot be directly observed.

Where Is All the Plastic? How Microplastic Partitions across Environmental Compartments within a Large Pelagic In-Lake Mesocosm.

How microplastics transit within aquatic ecosystems and partition among environmental compartments is not fully understood. To increase understanding, we added microplastic fragments ranging in buoyancy (positive: polyethylene (PE), neutral: polystyrene (PS), negative: polyethylene terephthalate (PET)) and size (∼30 to 1400 μm) to surface waters of closed-bottom, in-lake mesocosms (10 m diameter, 2 m depth). To assess residence time, we measured microplastics in surface waters and the water column over a 9-week period.

Tuning the Migration Order in Electrokinetic Separations of Cells.

Traditional analytical methods such as electrophoresis and chromatography have long been employed for separating bioparticles, particularly nanosized analytes. However, the efficient separation of micrometer-sized biological particles remains a challenge. Electrokinetic (EK) systems, particularly insulator-based EK (iEK) platforms, offer promising solutions by leveraging both linear and nonlinear electrokinetic phenomena to manipulate analyte migration and separation.

Caregiving Environmental Risk and Aggression From Infancy to Adolescence in a High-Risk Sample: An Examination of Between-Family and Within-Family Effects.

The dynamic, longitudinal interplay between caregiving environmental risk (e.g., caregiver postnatal substance use and psychological symptoms, caregiving instability, exposure to violence) and child aggression is not well understood, particularly for substance-exposed children.

Association between pica practice, oral health, and cariogenic microorganisms of US pregnant women: A cross-sectional study.

Objective: To investigate the effects of pica practices during pregnancy on oral health risks and outcomes.

Design: A cross-sectional study was conducted among pregnant women in New York. Demographic, medical history and oral hygiene practice data were collected using validated questionnaires.