90 results match your criteria: "Kocaeli Health and Technology University[Affiliation]"

The relatively complex functional anatomy of the mediobasal temporal region makes surgical approaches to this area challenging. Several studies describe various surgical approaches, along with their combinations and modifications, to reach lesions of this region. Some of these surgical approaches have been compared using artificial intelligence-based approaches that can be predicted, classified, and analyzed for complex data.

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Background: It is clear that nursing practice is directly affected by artificial intelligence (AI), and in this regard, a need is felt for more information on the knowledge and attitudes of nurses to the use of AI technology in nursing care practice. However, no inclusive measurement instrument tested for validity and reliability evaluating the attitudes of nurses to the use of AI technology was found. The aim of this research was to develop and test the validity of the Attitude Scale Towards the Use of Artificial Intelligence Technologies in Nursing (ASUAITIN) in the Turkish language.

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Introduction: According to the World Health Organization, adolescent pregnancy is defined as pregnancies of women aged 19 and below. The study aims to analyze the rates of adolescent pregnancies and maternal and fetal outcomes among births within the hospital and compare them with adult pregnancies.

Methods: The study is conducted retrospectively in one of Turkey's socio-economically underdeveloped provinces.

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ChatGPT has the ability to generate human-like text, analyze and understand medical images using natural Language processing (NLP) algorithms. It can generate real-time diagnosis and recognize patterns and learn from previous cases to improve accuracy by combining patient history, symptoms, and image characteristics. It has been used recently for learning about maxillofacial diseases, writing and translating radiology reports, and identifying anatomical landmarks, among other things.

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Introduction: High-frequency laser therapy has been increasingly used in several musculoskeletal disorders, but there is still a lack of evidence for the usage of the device in neck pain. This study aimed to compare the effectiveness of physiotherapy, high-frequency laser, and exercise therapy methods in the treatment of pain in cervical disk herniation.

Methods: It was a multicenter, randomized, controlled clinical trial.

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Therapeutic potential of adult stem cells-derived mitochondria transfer combined with curcumin administration into ARPE-19 cells in age-related macular degeneration model.

Tissue Cell

April 2025

Department of Stem Cell, Institute of Health Sciences, Kocaeli University, Kocaeli, Turkey; Center for Stem Cell and Gene Therapies Research and Practice, Kocaeli University, Kocaeli, Turkey; Department of Histology and Embryology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Objective: Mitochondria transfer from human Wharton's Jelly-derived mesenchymal stem cells (hWJ-MSCs-mt) and human endometrium-derived mesenchymal stem cells (hE-MSCs-mt), along with curcumin, were explored as potential treatments for age-related macular degeneration (AMD) caused by mitochondrial inefficiency, using a retinal model to assess impacts of curcumin and hWJ-MSCs-mt or hE-MSCs-mt on AMD.

Methods: ARPE-19 cells established an in vitro AMD model. Cells were exposed to 0-50 μM curcumin for 24 hours to determine optimal concentration by assessing their viability.

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This paper addresses the challenging task of itinerary recommendation for tourists and proposes an approach for suggesting efficient optimal itineraries in Istanbul, based on constraints. The paper presents an enhanced version of the genetic algorithm (GA), which aims to optimize the itineraries considering various constraints and preferences of the tourists. The improvement of the GA involved suggesting a customized fitness function tailored to address the complexities of the tourism problem, considering factors such as distance, time, cost, tourists' budget, and their desired activities and attractions.

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Article Synopsis
  • The Myval is a transcatheter heart valve developed by Meril Life Sciences that features an operator-friendly design for easier delivery and precise deployment.
  • It has shown effectiveness and safety in clinical studies, making it suitable for various complex heart valve procedures, including aortic valve implantation and pulmonary valve replacement.
  • The advancement of Myval signifies a step forward in cardiology, with a need for further long-term studies to confirm its benefits in improving patient outcomes and quality of life.*
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Views of nurses and midwives working in primary healthcare services on intimate partner violence against women.

Aust J Prim Health

November 2024

Mental Health and Psychiatric Nursing Department, Florence Nightingale Faculty of Nursing, Istanbul University - Cerrahpasa, Istanbul, Turkey.

Background Violence against women is a global public health problem. Primary healthcare services and health workers play an important role in managing this problem. The aim was to identify barriers and facilitators to the identification and management of intimate partner violence (IPV) among women presenting to primary healthcare services from the perspective of nurses/midwives, and to identify the challenges and needs to improve practices.

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Background/purpose: The objective of this study was to assess the root apical closure ages of first permanent molars retrospectively among a group of western Turkish children aged between 5 and 15 years using cone-beam computed tomography (CBCT).

Materials And Methods: CBCT images of 202 patients were examined. The patients were divided into 7 groups according to age: ≤8 years, 8-8.

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Article Synopsis
  • Monkeypox (Mpox) is an Orthopoxvirus causing skin blisters with a mortality rate of 0-10% and has seen an increase in cases since the end of global smallpox vaccinations.
  • This review discusses updates on Mpox's transmission, symptoms, diagnosis, prevention, and treatment, highlighting the role of AI in predicting the disease.
  • Key prevention strategies involve PCR testing for early detection, vaccination with JYNNEOS and ACAM2000, and minimizing contact with symptomatic individuals, similar to STI prevention practices.
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Introduction:  Previous studies have shown that isolated eyelid myokymia (EM) is usually caused by stress, fatigue, and caffeine consumption. The purpose of this study was to evaluate the association between EM and digital screen time, uncorrected refractive error, intraocular pressure (IOP), and blood electrolyte levels.

Methods: Between February 2023 and June 2024, 103 eyes of 103 patients who applied to the ophthalmology outpatient clinic with complaints of eyelid twitching lasting for more than two weeks and 103 eyes of 103 healthy individuals as a control group were included in the study.

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Article Synopsis
  • The study focuses on developing a new drug, "IHNOCS," aimed at treating Head, Neck, and Oral Cancer by targeting specific proteins to suppress cancer progression.
  • Using advanced computational tools, researchers demonstrated that IHNOCS effectively inhibits the KRTAP2-3 protein and modulates TGF-β, which helps to slow down cancer metastasis.
  • While the drug shows promising results in theory, it will need to go through further experimental testing, including lab studies and clinical trials, to evaluate its effectiveness in real-world situations.
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In this study, a new amperometric biosensor was developed for glucose determination. For this purpose, polyaniline-polypyrrole-poly(sodium-4-styrenesulfonate) film was prepared by electropolymerization of aniline and pyrrole with poly(sodium-4-styrenesulfonate) on a platinum plate. The best working conditions of the polyaniline-polypyrrole-poly(sodium-4-styrenesulfonate) film were determined.

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Objectives: Acute pulmonary embolism (PE) is a potentially life-threatening condition characterized by the sudden blockage of the pulmonary arteries. Although the MAGGIC risk score has emerged as a valuable tool in predicting outcomes in patients with chronic heart failure, it has also been demonstrated and identified as a prognostic model in various cardiac diseases other than heart failure. In this study, we aimed to investigate the relationship between MAGGIC score and adverse outcomes in patients with PE.

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Introduction: Prostate cancer has emerged as a widespread health concern, with systemic inflammation believed to substantially contribute to its development and progression. The presence of systemic inflammatory responses has been established as an independent predictor of unfavorable long-term outcomes in prostate cancer patients. The goal of this study is to inhibit RXRα and RXRβ receptors, which are involved in prostate cancer, with Luteolin, Formononetin, and Kaempferol, with varying success.

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Industrial waste contaimnation of water sources is a serious environmental problem. As a result, it's critical to identify metallic contamination in water with precision, sensitivity, and accuracy. In acetonitrile, the fluorimetric parameters of N,N-'bis(2,5-dihydroxybenzylidene)-4,4'-diamino diphenyl ether (DHDPE) and aluminum complex were determined.

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Objectives: In this study, we aimed to evaluate the effectiveness of osteopathic visceral manipulation (OVM) combined with physical therapy in pain, depression, and functional impairment in patients with chronic mechanical low back pain (LBP).

Patients And Methods: A total of 118 patients with chronic mechanical LBP were assessed, and 86 who met the inclusion criteria were included in the randomized-controlled study between January 2021 and August 2022. The patients were randomized to either Group 1 (n=43), which underwent physical therapy (5 days/week, for a total of 15 sessions) combined with OVM (2 days/week with three-day intervals), or Group 2 (n=43), which underwent physical therapy (5 days/week, for a total of 15 sessions) combined with sham OVM (2 days/week with three-day intervals).

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Introduction Multiple sclerosis (MS) is a chronic and autoimmune disease that has a significant influence on the central nervous system, such as the brain and spinal cord, affecting millions of individuals globally. Understanding the connection between subcortical brain regions and MS is crucial for effective diagnostic and therapeutic approaches for treating this disabling disease. This study explores the relationship between volume and contours of asymmetry index of subcortical brain regions in individuals with MS using volBrain software (https://www.

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In this study, it was aimed to determine the effect of white noise on anxiety levels and breastfeeding success of primipara mothers having vaginal delivery. The research was conducted using a randomized controlled experimental design. The research was conducted at a public hospital located in western Turkey.

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Purpose: To investigate the association of pre-photorefractive keratectomy Schirmer-1 test value with post-photorefractive keratectomy central corneal epithelial thickness, ocular surface disease index score, and uncorrected distance visual acuity.

Methods: Patients were categorized according to preoperative Schirmer-1 value: the normal Schirmer Group (n=54; Schirmer-1 test value, >10 mm) and the low Schirmer Group (n=52; Schirmer-1 test value, between 6 and 10 mm). We analyzed ablation depth, visual acuity, result of Schirmer-1 test (with anesthesia), tear film break-up time, ocular surface disease index score, central corneal epithelial thickness, and spherical equivalent refraction.

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Investigation of the differentiation potential of pericyte cells as an alternative source of mesenchymal stem cells.

Acta Histochem

April 2024

Department of Stem Cell, Institute of Health Sciences, Kocaeli University, Kocaeli, Turkey; Center for Stem Cell and Gene Therapies Research and Practice, Kocaeli University, Kocaeli, Turkey; Department of Medical Biology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.

Background: The mesenchymal stem cells (MSCs) with characterized by their multipotency and capacity to differentiate into various tissue cell types, have led to their incorporation in regenerative medicine research. However, the limited numbers of MSCs in the human body and their diverse differentiation capabilities in tissues highlight the need for exploring alternative regenerative cell sources. In this study, therefore, we conducted molecular level examinations to determine whether pericytes, specialized cell communities situated near blood vessels, could serve as a substitute for human bone marrow-derived mesenchymal stem cells (hBM-MSCs).

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A 78-year-old male patient with a history of coronary artery disease (he had undergone coronary artery bypass surgery 4 years ago), heart failure with mildly reduced ejection fraction, diabetes mellitus, and transient ischemic attack presented to the emergency department with complaints of dyspnea (New York Heart Association Class 4) despite the optimal medical therapy.

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Purpose: To evaluate retrobulbar adipose tissue of patients with active and inactive Graves' orbitopathy (GO) by shear-wave ultrasound elastography (SWE).

Methods: Followed-up in our ophthalmology clinic due to GO, 72 eyes of 36 patients and 38 eyes of 19 healthy controls were included in this cross-sectional case-control study. Graves' patients were divided into two subgroups under clinical activity score (CAS): active Graves' orbitopathy (AGO) (CAS ≥ 3) and inactive Graves' orbitopathy (IGO) (CAS < 3).

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