Influence of substance loss and restoration materials on the fracture resistance of 1-piece endodontic crowns: An in vitro study.

Statement Of Problem: How different restorative materials designed for computer-aided design and computer-aided manufacturing (CAD-CAM) and substance loss affect the fracture resistance of endodontically treated maxillary first premolars restored with 1-piece endodontic crowns is unclear.

Purpose: The purpose of this in vitro study was to assess the impact of various CAD-CAM restorative materials and residual tooth structure on the fracture resistance of endodontically treated maxillary first premolars restored with 1-piece endodontic crowns.

Material And Methods: Sixty-four maxillary first premolars were endodontically treated and divided into 4 main groups (n=16) according to the restorative material: ZP: Zirconia 1-piece endodontic crowns group (IPS e.

Prediction of QTc Prolongation in Acute Poisoning with Atypical Antipsychotics Using Machine Learning Techniques: A Study from Poison Control Center.

Atypical antipsychotics have experienced a significant increase in use across various disorders, coinciding with a rise in acute intoxication. This retrospective study predicts prolonged QTc interval and the necessity for mechanical ventilation (MV) in patients with acute atypical antipsychotic poisoning using machine learning techniques. This retrospective study included 355 patients with a mean age of 26.

Assessment of sexual dimorphism in all lumbar vertebrae using three-dimensional multi-slice computed tomography scan.

Sex determination is a critical step in identification. Scarce studies assessed the sexual dimorphism of specific lumbar vertebrae in Egyptians. This prospective study which enrolled 134 Egyptians assessed the sexual dimorphism of lumbar vertebrae using multi-slice computed tomography.

Assessing Self-medication Practices Among Healthcare Providers With Migraine in Saudi Arabia.

Objectives: Migraine is a neurological disorder characterized by recurrent headaches resulting from abnormal regulation of sensory input to the head. Self-medication (SM) is a prevalent practice among healthcare providers (HCPs), with potentially detrimental consequences. This study aims to investigate SM practices among HCPs in Saudi Arabia, specifically focusing on their management of migraines.

The triad of excellence in oncology nursing: The synergy of clinical governance climate, digital health competence, and patient-centered care.

Purpose: Patient-centered care competency is vital for oncology nurses to provide high-quality, individualized cancer care. A strong clinical governance climate fosters accountability, ethical decision-making, and continuous improvement, yet its role in oncology nursing remains underexplored. Additionally, the impact of digital health competence in strengthening the clinical governance-patient-centered care relationship is unclear.

Ethical Awareness in the Use of Large Language Models: Development and Validation of a Scale for Healthcare Professionals.

Background: The integration of large language models (LLMs) into healthcare offers transformative potential but raises significant ethical challenges. Addressing these challenges requires a comprehensive framework to assess healthcare professionals' ethical awareness of LLMs usage.

Objective: To develop and validate a scale designed to evaluate healthcare professionals' ethical awareness regarding the integration of LLMs into clinical practice.

Amlodipine and frusemide: pharmacological factors contributing to increased fall risk in concurrently treated patients - a retrospective cross-sectional study.

Background: Calcium channel blockers, such as amlodipine, are commonly prescribed for hypertension but can cause peripheral edema, often requiring adjunctive frusemide. Concerns exist regarding the potential increase in fall risk, particularly in older populations. However, few studies have assessed the prevalence of amlodipine and frusemide combination (AFC) prescriptions and their association with fall risk factors.

Association between proton pump inhibitors and anti-coagulants for a better prevention of gastrointestinal bleeding.

Background And Aim: Gastrointestinal bleeding (GIB) is one of the most common medical emergencies. Proton pump inhibitors (PPI) are among the most widely used drugs in gastroenterology to treat various types of acid-related disorders. We aim to investigate the safety of proton pump inhibitors (PPIs) when used concurrently with anticoagulants in patients with upper and lower gastrointestinal bleeding (GIB) and assess the risk of hospitalization, GIB, and mortality in patients receiving this combined treatment.

Evaluation of sexual dimorphism in the foramina of the middle cranial fossa using high-resolution multi-slice computed tomography scan: A cross-sectional study.

Introduction: Sex estimation is a primary concern in forensic medicine. Although few studies have investigated sexual dimorphism in the middle cranial fossa, the obtained findings are still inconsistent.

Methods: A cross-sectional study was conducted to investigate the sexual dimorphism in three foramina [foramen ovale, foramen rotundum, and foramen spinosum] using a high-resolution 128 multi-slice three-dimensional (3D) computerized tomography scanner.

Dentists' role in oral care for head and neck cancer patients in GCC countries.

This study evaluates dentists' knowledge of oral and dental procedures before and after radiotherapy for head and neck cancer patients in Gulf Cooperation Council (GCC) countries. A web-based cross-sectional survey was distributed via social media to dentists in six GCC countries, assessing knowledge of pre- and post-radiotherapy oral care. Data were analysed using descriptive statistics, Chi-square tests, and logistic regression.

Risk Factors for Surgical Site Infections in Elective and Emergency Surgeries: A Prospective Cohort Study.

Background: Surgical site infections (SSIs) cause morbidity, disabilities, and healthcare costs. This study aims to assess patient- and surgery-related factors influencing SSIs with standardized preoperative, operative, and postoperative care.

Methods: This prospective cohort study involved 140 patients undergoing elective or emergency surgeries at Al-Azhar University Hospitals, Egypt, from October 2020 to September 2021.

Prenatal Interventions for Congenital Diaphragmatic Hernia: A Systematic Review.

Life-threatening congenital diaphragmatic hernia (CDH) is a defect with subsequent herniation of abdominal organs. Herniation of abdominal organs into the thoracic cavity causes pulmonary hypoplasia and hypertension. Despite improved baby critical care and surgical therapy, severe CDH has high mortality and morbidity rates.

The Impact of Digital Culture, Digital Competence and Clinical Decision Support System Usability on Critical Care Nurses' Clinical Judgement: A Moderated Moderation Analysis.

Background: In the context of increasingly digital healthcare systems, clinical judgement among critical care nurses is shaped not only by clinical experience but also by the broader digital environment. Digital culture, digital competence and clinical decision support systems (CDSSs) usability are pivotal factors influencing how nurses make timely, informed clinical decisions. However, the complex interplay among these factors remains underexplored.

Evaluating dental students' understanding of oral complications and care management for head and neck cancer patients.

Background: Advancements in head and neck cancer treatments have improved survival rates, but complications in the mouth's soft and hard tissues can hinder treatment effectiveness or cause interruptions. Dentists play a critical role in managing these oral complications, helping to enhance the overall success of cancer treatments. The aim of this study is to serve as a foundation to assess the knowledge base of senior dental students and dental interns in Saudi Arabi regarding their preparedness to manage oral health challenges in cancer patients.

Characteristics, mechanisms, and medicolegal perspectives of fatal cardiothoracic injuries in a tertiary care center.

This study aims to investigate the medicolegal aspects of cardiothoracic trauma, including injury patterns, mechanism of infliction, survival time, predictors, and mechanism of mortality. A prospective cohort study included 229 cardiothoracic traumatized patients admitted to the Emergency Departments, who were categorized into patients with fatal or nonfatal injuries. Males constituted more than seven times the females with a 22.

Chrysin and Bone Marrow-derived Mesenchymal Stem Cells Restrain Complete Freund's Adjuvant-induced Arthritis in Wistar Rats via Subsiding Inflammation and Oxidative Stress.

Introduction: Rheumatoid arthritis (RA) is an inflammatory disease that causes significant disability and persistent inflammation. Currently, there are no appropriate treatments for RA other than systemic immunosuppressants, which have a variety of undesirable effects after long-term use. Thus, this study aims to determine the anti-arthritis effect of chrysin (5,7-dihydroxyflavone) and/or bone marrow-derived mesenchymal stem cells (BM-MSCs), separately and combined, on CFA (complete Freund's adjuvant)-induced arthritis in rats as an animal model of RA.

Development of AI-Enhanced Smile Design Software for Ultra-Customized Aesthetic Outcomes.

Background: Advancements in artificial intelligence (AI) have paved the way for ultra-customized aesthetic solutions in dentistry, particularly in smile design. Conventional smile design methods often fall short in providing a fully personalized outcome, necessitating the development of AI-enhanced software to optimize results by considering facial features, dental parameters, and patient preferences.

Materials And Methods: A prototype AI-enhanced smile design software was developed using a combination of convolutional neural networks for facial analysis and generative adversarial networks for creating customized smile designs.

Assessment of Platelet-Rich Fibrin (PRF) in Enhancing Periodontal Regeneration.

Background: Restoring the structure and functionality of periodontal tissues is the goal of the intricate biological process known as periodontal regeneration. Autologous blood products like platelet-rich fibrin (PRF) have drawn interest because of their capacity to hasten healing and encourage tissue regeneration.

Materials And Procedures: This randomized clinical study included 30 patients with chronic periodontitis who needed regenerative periodontal treatment.

Evaluation of Different Surface Treatments on Osseointegration of Dental Implants.

Background: Osseointegration is a critical factor determining the success of dental implants. Various surface treatments are applied to enhance the integration of implants with the surrounding bone tissue.

Materials And Methods: Standardized dental implants were divided into four groups based on the surface treatment applied: Group A (machined surface), Group B (sandblasted and acid-etched), Group C (plasma-sprayed hydroxyapatite coating), and Group D (titanium oxide nano-coating).

The Effect of Different File Motions on the Formation of Apical Debris During Root Canal Preparation.

Background: The formation of apical debris is a common occurrence during root canal preparation, which may cause postoperative complications like pain and infection. Different file motions-rotary, reciprocating, and adaptive-can influence the extent of debris extrusion.

Materials And Methods: A total of 90 extracted single-rooted teeth were randomly divided into three groups ( = 30) based on the file motion used: Group 1-rotary, Group 2-reciprocating, and Group 3-adaptive motion.

Assessment of Bone Regeneration Around Implants Using Different Bone Substitute Materials.

Background: Bone regeneration around dental implants is critical for the success of implant therapy, especially in patients with compromised bone quality or volume. The choice of bone substitute materials plays a pivotal role in enhancing osseointegration and bone regeneration.

Materials And Methods: A total of 40 patients requiring dental implant placement with bone augmentation were included in this prospective study.

Comparative Analysis of the Color Stability of Different Ceramic Materials after Exposure to Staining Solutions.

Background: Color stability is a critical factor influencing the aesthetic success of ceramic materials in dentistry. This study evaluates and compares the color stability of three commonly used ceramic materials-lithium disilicate, zirconia, and feldspathic porcelain-after exposure to staining solutions to determine their clinical performance under challenging oral conditions.

Materials And Methods: A total of 60 ceramic specimens (20 from each material group) were fabricated and polished to standardized dimensions.