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Purpose: This clinical focus article describes the role that treatment intensity plays in social communication interventions utilizing augmentative and alternative communication for learners who have complex communication needs associated with intellectual disability and/or autism spectrum disorder.
Method: We delineate the parameters that comprise a frequently used treatment intensity taxonomy and provide an overview of the extant literature pertaining to treatment intensity as it applies to social communication interventions that include augmentative and alternative communication. Next, we describe several additional variables that complement treatment intensity frameworks and summarize the need for more rigorous methodological descriptions of intervention procedures in social communication intervention studies.
Conclusions: Applications of treatment intensity frameworks represent an important component of designing and implementing replicable communication intervention protocols for individuals with complex communication needs. Complete, clear reporting of treatment intensity parameters and relevant treatment variables in the extant evidence is necessary for the benefits of a treatment intensity framework to be optimally realized for evidence-based social communication interventions for individuals with complex needs.
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http://dx.doi.org/10.1044/2025_AJSLP-24-00300 | DOI Listing |
J Cosmet Dermatol
September 2025
Department of Dermatology, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, China.
Purpose: To evaluate the efficacy and underlying mechanism of advanced optimal pulse technology intense pulsed light (AOPT) in low-energy triple-pulse long-width mode (AOPT-LTL) for melasma treatment.
Methods: An in vivo guinea pig model of melasma was established through progesterone injection and ultraviolet B radiation. Three sessions of AOPT-LTL treatment were performed weekly.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2025
Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha 410008.
Objectives: Patients with connective tissue diseases (CTD) have a high incidence of cardiac involvement, which often presents insidiously and can progress rapidly, making it one of the leading causes of death. Multiparametric cardiovascular magnetic resonance (CMR) provides a comprehensive quantitative evaluation of myocardial injury and is emerging as a valuable tool for detecting cardiac involvement in CTD. This study aims to investigate the correlations between CMR features and serological biomarkers in CTD patients, assess their potential clinical value, and further explore the impact of pre-CMR immunotherapy intensity on CMR-specific parameters, thereby evaluating the role of CMR in the early diagnosis of CTD-related cardiac involvement.
View Article and Find Full Text PDFNeuropsychopharmacol Rep
September 2025
Department of Anesthesiology and Pain Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.
Background: Although opioid analgesics may influence sleep in patients with chronic pain, the association between strong opioid use and sleep characteristics remains unclear. This study aimed to explore differences in sleep status among chronic pain patients with varying levels of opioid use.
Methods: A total of 29 patients with chronic non-cancer pain who had been under treatment for more than 6 months were included.
BMB Rep
September 2025
Department of Microbiology, Jeonbuk National University Medical School, Jeonju 54896; Department of R&D, Cutiimunebio Inc., Jeonju 54907, Korea.
Atopic dermatitis (AD) is a chronic dermatological disorder characterized by intense pruritus and eczematous lesions. Repeated topical application of 2,4-dinitrofluorobenzene (DNFB) in NC/Nga mice produces AD-like clinical symptoms that closely resemble human AD. N-Acetyl-L-Alanine (L-NAA), a derivative of L-Alanine, has unknown biological and physiological effects on cutaneous tissue.
View Article and Find Full Text PDFStress
December 2025
Department of Clinical and Health Psychology, University of Vienna, Vienna, Austria.
Music listening may decrease pain via psychobiological mechanisms. Music listening style (MLS) influences music processing: Music empathizers (ME) focus on emotional aspects of music, whereas music systemizers (MS) focus on structural aspects, potentially affecting processes of music-induced analgesia. The effects of the MLS on music-induced analgesia might depend on the source of music selection (i.
View Article and Find Full Text PDF