98%
921
2 minutes
20
To evaluate B-scan echographic features of endophthalmitis for their correlation with disease characteristics and long-term vision outcomes. Patients diagnosed with endophthalmitis at Massachusetts Eye and Ear between 2011 and 2021 were recruited (N = 209). Data included demographics, infection source, initial therapy, and findings from culture isolates, best corrected visual acuity (BCVA), slit lamp, and B-scan ultrasonography. More patients with positive microbial cultures, versus those with negative cultures, had dense vitreous debris on initial B-scan ( = .008). Patients whose initial slit lamp examination provided difficult/no view into the anterior chamber had more frequent findings of retinal detachment (RD) and T-sign ( < .001 and = .016, respectively) and worse final mean BCVA ( < .001) versus patients with adequate views. Patients with dense vitreous opacities (VO) on initial B-scan had significantly worse initial mean BCVA versus patients with mild or moderate VO ( .001 and = .013, respectively) and had significantly worse final mean BCVA versus patients with mild VO ( .001). Final mean BCVA was significantly worse in patients with choroidal detachment (CD), RD, or T-sign than in patients without these features (each < .001). Reductions in VO and vitreous membranes were observed at 1 month postpresentation, whereas CD was significantly more common at 1 week and RD more common at 1 month postpresentation. Positive cultures, specific microbial species, and B-scan findings (dense VO, CD, RD, and T-sign) are independent predictors of worse vision outcomes in patients with endophthalmitis.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405197 | PMC |
http://dx.doi.org/10.1177/24741264251364818 | DOI Listing |
Am J Ophthalmol
September 2025
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Topic: The aim of this systematic review and meta-analysis is to evaluate best-corrected visual acuity (VA) outcomes following transscleral cyclophotocoagulation (TSCPC) in patients with refractory glaucoma.
Clinical Relevance: TSCPC is typically reserved for cases of refractory glaucoma, due to apprehension of negative affects on VA. Prior studies have reported the VA outcomes from TSCPC, but no comprehensive review of the literature has yet been conducted.
Am J Ophthalmol
September 2025
Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Objective: To examine the safety and effectiveness of non-inverted ILM Free Flap combined with the SPOT technique (Sub-Perfluorocarbon liquid (PFCL) injection of Ocular viscoelastic device (OVD) Technique) in the treatment of unclosed macular holes (MHs).
Design: Retrospective interventional case series.
Participants: Eight patients (8 eyes) with persistent unclosed MHs were treated at a tertiary eye hospital in China from September 2023 to February 2025.
J Vitreoretin Dis
September 2025
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
To evaluate B-scan echographic features of endophthalmitis for their correlation with disease characteristics and long-term vision outcomes. Patients diagnosed with endophthalmitis at Massachusetts Eye and Ear between 2011 and 2021 were recruited (N = 209). Data included demographics, infection source, initial therapy, and findings from culture isolates, best corrected visual acuity (BCVA), slit lamp, and B-scan ultrasonography.
View Article and Find Full Text PDFClin Ophthalmol
August 2025
Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Background: Diabetic macular edema (DME) is a leading cause of vision loss in working-age adults. Faricimab, a bispecific antibody targeting VEGF and Ang-2, has been shown to reduce treatment burden by enabling extended injection intervals. However, real-world, long-term data from Japanese populations are limited.
View Article and Find Full Text PDFRetina
August 2025
University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Miami, FL, USA.
Purpose: To analyze the relationship between socioeconomic status (SES) and neovascular age-related macular degeneration (nAMD) outcomes and management.
Methods: Retrospective analysis of 1449 patients diagnosed with nAMD, treated with anti-VEGF between January 2016-January 2024.
Results: Lower income was associated with poorer baseline (p < .