Evaluation and Management of Uveitis in a Patient With AIDS With Low CD4 Count and Prior CMV Retinitis.

To report an unusual case of uveitis in a patient with AIDS with low CD4 count. A single case was evaluated. A 28-year-old man with AIDS, central nervous system lymphoma, and cytomegalovirus (CMV) viremia developed subacute vitritis in the left eye.

Effects of Socioeconomic Factors on Visual Outcome and Management of Wet Age-Related Macular Degeneration Patients.

Purpose: To analyze the relationship between socioeconomic status (SES) and neovascular age-related macular degeneration (nAMD) outcomes and management.

Methods: Retrospective analysis of 1449 patients diagnosed with nAMD, treated with anti-VEGF between January 2016-January 2024.

Results: Lower income was associated with poorer baseline (p < .

Indications and Outcomes of Select Vitreoretinal Surgery in Patients With Marfan Syndrome.

To report clinical indications and outcomes of select vitreoretinal surgery in patients with Marfan syndrome. A retrospective consecutive case series of patients with Marfan syndrome undergoing surgery was performed. Data collected included demographics, systemic and ocular history, refraction, and preoperative and postoperative examination findings.

"Retinal Displacement Following Retinectomy in Complex Macula-Involving Recurrent Rhegmatogenous Retinal Detachment".

Purpose: To assess the incidence and degree of retinal displacement following nonprimary retinectomy in macula-involving rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR).

Methods: A retrospective interventional case series was conducted on eyes that underwent a second surgery involving retinectomy for complex macula-involving RRD between December 2011 and September 2023 at the Bascom Palmer Eye Institute. Clinical records and imaging were analyzed to assess the incidence and degree of retinal displacement using postoperative fundus autofluorescence (FAF).

Optical Coherence Tomography in Retinal Detachment: Prognostic Biomarkers, Surgical Planning, and Postoperative Monitoring.

Retinal detachment (RD) is a vision-threatening ocular emergency that necessitates rapid diagnosis and intervention. This review examines the evolving role of optical coherence tomography (OCT) in RD by synthesizing the literature on preoperative biomarkers and advanced image modalities that inform diagnosis, prognosis, and surgical planning. We evaluated studies employing spectral-domain OCT, swept-source OCT, OCT angiography, adaptive optics OCT, and en face OCT to assess photoreceptor integrity, retinal detachment height, intraretinal cystic cavities, outer retinal corrugations and undulation, and macular involvement.

Evaluating the necessity of topical and subconjunctival antibiotic prophylaxis in ocular surgery.

Purpose Of Review: The role of topical and subconjunctival antibiotics in reducing infection risk in major ocular surgeries remains unclear despite their widespread use. This review discusses the efficacy of both administration routes across various forms of surgery, underscoring evidence-based recommendations for quality practice patterns and limitations in current research.

Recent Findings: Although intracameral antibiotics consistently result in low infection rates in phacoemulsification procedures, there may be some role for topical and subconjunctival antibiotic use, also influenced by regional preferences.

Characteristics and Medical Accuracy of Online Discussions of Retinal Conditions on a Social Media Platform.

To assess the content and medical accuracy of retina-related patient discussions on Reddit, an anonymous social media platform, to better understand the main concerns and reliability of a highly accessible resource. A cross-sectional analysis was performed of the top 20 posts and top 3 comments from 2011 to 2022 on the Reddit subforums r/Optometry and r/EyeTriage containing the following keywords: "retinal detachment", "macular edema", "macular degeneration", and "diabetic retinopathy". This study assessed 407 posts and comments.

Clinical trials and real-world studies examining faricimab and high-dose aflibercept for wet age-related macular degeneration and diabetic macular edema.

Purpose Of Review: The goal of this review is to summarize emerging clinical trial and real world evidence for faricimab and high dose aflibercept (8 mg), two recently approved treatments for wet age-related macular degeneration and diabetic macular edema.

Recent Findings: Faricimab, a bispecific monoclonal antibody targeting vascular endothelial growth factor (VEGF) and angiopoietin-2, and high-dose aflibercept have demonstrated significant potential for extending treatment intervals while maintaining efficacy. Pivotal clinical trials such as YOSEMITE, and RHINE established faricimab to be noninferior to standard anti-VEGF therapy with superior durability.

Disparities Between Clinical Trial Recruitment and Real-World Demographics in Macular Edema Secondary to Retinal Vein Occlusion.

Purpose: Clinical trial cohorts frequently differ demographically from the overall population receiving treatment for the condition under study. Our study describes the racial, ethnic, and gender composition of the cohorts of retinal vein occlusion (RVO) macular edema (ME) clinical trials and compares this to the racial, ethnic, and gender composition of patients undergoing treatment for ME secondary to RVO from the (Intelligent Research in Sight) IRIS Registry.

Design: Retrospective observational case series Subjects: Participants in RVO-ME clinical trials that met the following inclusion criteria: conducted in the United States of America, Phase III completed, data reported between January 1, 2000, and January 1, 2020, and demographic information reported with results.

A New Era of Ophthalmology Leadership? A Descriptive and Comparative Analysis of Ophthalmology Department Chairs in 2024.

Purpose: To (1) characterize and analyze the demographics and scholarly achievements of United States (US) academic ophthalmology department chairs, and (2) to elucidate trends in the academic and demographic profiles of newly hired department chairs.

Design: Cross-sectional study.

Methods: Online search of publicly available resources conducted January 1, 2024.

Potential Gaps in Eye Care Based on Evaluation of Federally Qualified Health Centers.

Importance: Federally qualified health centers (FQHCs) are federally funded community health clinics that provide comprehensive care to underserved populations, making them potential opportunities to offer eye care and address unmet health care needs. Evaluating the presence of eye care services at FQHCs in Florida is important in understanding and addressing possible gaps in care for the state's large uninsured and underserved populations.

Objective: To determine whether FQHCs in Florida are currently offering eye care services, where they are available, what services are being offered, and who provides them.

Medical Accuracy of Reddit in Patient Discussions of Prospective Ocular Stem Cell Therapies for Retinal Degenerative Diseases.

To evaluate the medical accuracy in discussions of stem cell therapy for retinal diseases on a social media internet forum (Reddit). A cross-sectional study assessed 11 Reddit forums and 411 unique comments from 2017 to 2022. Evaluated participants were all anonymous Reddit users.

Review and analysis of history and utilization of panretinal photocoagulation and ranibizumab after publication of protocol S.

Purpose Of Review: We describe the history, utilization, and series results of panretinal photocoagulation (PRP) and ranibizumab and provide an analysis of PRP and ranibizumab usage before versus after the publication of the 2-year and 5-year results of the Diabetic Retinopathy Clinical Research Network (DRCR.net) Protocol S trial.

Recent Findings: Number of ranibizumabs performed began to increase and number of PRPs performed began to decrease in 2016.

Management of vitreous floaters: a review.

Purpose Of Review: Vitreous floaters, characterized by the perception of spots or shadows in the visual field, commonly result from posterior vitreous detachment and can cause chronic symptoms in affected patients. The diagnosis of posterior vitreous detachment is typically determined clinically and can sometimes be confirmed with optical coherence topography (OCT) [1 ▪▪ ] . The objective of this review is to review management options for symptomatic vitreous floaters.

Geographic Trends in Ophthalmology Resident Physician Compensation and Cost-of-Living Expenses.

Importance: Given that resident physician financial strain has been associated with poor outcomes, objective metrics to forecast financial well-being may be useful to (1) applicants when evaluating ophthalmology residency programs and (2) programs when determining resident benefits.

Objectives: To determine and compare the relative value of ophthalmology resident stipends plus benefits when adjusted for cost-of-living expenses and to analyze program characteristics associated with greater resident net incomes.

Design, Setting, And Participants: In this cross-sectional study, the American Medical Association's Fellowship and Residency Electronic Interactive Database was used to identify US Accreditation Council for Graduate Medical Education-accredited ophthalmology residency programs.

Update on "Cell Therapy" Clinics Offering Treatments of Ocular Conditions Using Direct-To-Consumer Marketing Websites in the U.S.

Purpose: To assess the scope of U.S.-based companies advertising and administering non-Federal Drug Administration (FDA) approved cell-based therapy (herein called NFACT) for ocular conditions based on information from companies' public websites after the FDA's legal actions against specific NFACT clinics in 2018 and 2019.