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Purpose: Coronary artery bypass grafting (CABG) is an essential intervention for treating coronary artery disease. However, the effectiveness of postoperative rehabilitation often depends on the implementation of early mobilization by patients. In practice, adherence to early mobilization post-CABG is frequently suboptimal. This study focuses on patients who have successfully implemented early activity post-CABG, exploring the situational factors that facilitate early mobilization.
Patients And Methods: Semi-structured interviews were conducted with 15 post-CABG patients from three hospitals in Shanghai who had successfully implemented early mobilization. Data collection was conducted from October 1, 2024 to December 31, 2024. Utilizing a constructivist grounded theory approach, the interview guide was modified based on emerging themes throughout the study.
Results: Patients who successfully implement early mobilization typically undergo three main stages: intention, initiation, and maintenance. The study identified three main domains influencing these phases: Core Context (including the perception of the importance of exercise rehabilitation, understanding and beliefs about early mobilization, positive personal experiences with physical activity, and observing positive outcomes from others' activities); Essential Conditions (including physical condition, psychological preparedness, knowledge literacy, and initial outcomes); External Factors (including the atmosphere and promotion of early mobilization, the development of an exercise rehabilitation system from pre-surgery to ICU to ward, and social support).
Conclusion: This study provides a new perspective by examining the situational factors associated with the successful implementation of early mobilization after CABG. By focusing on successful cases, healthcare professionals can better understand the implementation process and experiences, enabling them to develop targeted interventions to improve adherence.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407002 | PMC |
http://dx.doi.org/10.2147/PPA.S537861 | DOI Listing |
JCI Insight
September 2025
Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, United States of America.
Impaired muscle regrowth in aging is underpinned by reduced pro-inflammatory macrophage function and subsequently impaired muscle cellular remodeling. Macrophage phenotype is metabolically controlled through TCA intermediate accumulation and activation of HIF1A. We hypothesized that transient hypoxia following disuse in old mice would enhance macrophage metabolic inflammatory function thereby improving muscle cellular remodeling and recovery.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Polytrauma patients are defined by the Berlin Consensus as those with severe injuries across multiple regions and require complex, adaptable treatment approaches to address both immediate and long-term needs of the patient, while considering the resource availability. This review evaluates early total care (ETC), which attempts early definitive fixation, against damage control orthopedics (DCO), which focuses on temporary stabilization to reduce physiological strain from surgery. While ETC promotes early mobilization, DCO reduces risks and subsequent complications associated with the "second hit" phenomenon in critically ill patients.
View Article and Find Full Text PDFDev Biol
September 2025
Department of Molecular Biosciences, Northwestern University, Evanston IL 60208; Robert Lurie Comprehensive Cancer Center, Northwestern University, Evanston IL 60208. Electronic address:
The activation of progenitor cells near wound sites is a common feature of regeneration across species, but the conserved signaling mechanisms responsible for this step in whole-body regeneration are still incompletely understood. The acoel Hofstenia miamia undergoes whole-body regeneration using Piwi+ pluripotent adult stem cells (neoblasts) that accumulate at amputation sites early in regeneration. The EGFR signaling pathway has broad roles in controlling proliferation, migration, differentiation, and cell survival across metazoans.
View Article and Find Full Text PDFJBJS Essent Surg Tech
September 2025
Division of Hand and Reconstructive Microsurgery, Department of Orthopedics, Olympia Hospital & Research Centre, Trichy, Tamilnadu, India.
Background: Hemi-hamate osteochondral grafting is a surgical technique that is utilized to reconstruct the proximal interphalangeal (PIP) joint in cases of unstable dorsal fracture-dislocation with >50% articular surface involvement. However, hemi-hamate osteochondral grafting can be technically challenging, has been reported to have various technical modifications, and can lead to complications such as overstuffing of the joint. This surgical technique article describes successful PIP joint reconstruction with use of a hemi-capitate osteochondral graft, which may offer a viable alternative to hemi-hamate osteochondral graft.
View Article and Find Full Text PDFJ Educ Health Promot
July 2025
Shahid Ashrafi Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Acute myocardial infarction (MI), as a serious and fatal heart disease and an important medical emergency, imposes the large financial burden on the health and treatment systems of countries and the family economy. In the meantime, starting rehabilitation programs after acute myocardial infarction as soon as possible can minimize the unfortunate and irreparable side effects. Therefore, the present study was conducted with the aim of evaluating the effectiveness of an educational program on health index in the MI patients hospitalized in CCU ward.
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