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Article Abstract

Six sesquiterpene derivative compounds (1-6), including one new 7R-sydowic acid (1) and five known compounds (2-6) were isolated from the secondary metabolites of Aspergillus sydowii-HB. The structures were determined by NMR spectroscopy and ESI-MS analysis, and the configuration of compound 1 was confirmed through DP4 calculation and NMR chemical shift. All the isolated compounds (1-6) were tested for their cytotoxic activities. The possible biosynthetic pathways for compounds (1-6) were also postulated.

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http://dx.doi.org/10.1002/mrc.70035DOI Listing

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