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http://dx.doi.org/10.1002/lary.70111 | DOI Listing |
Am J Hum Genet
September 2025
Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, Rotterdam 3000 CA, the Netherlands.
Microtubule-actin cross-linking factor 1 (MACF1) is a large protein of the spectraplakin family, which is essential for brain development. MACF1 interacts with microtubules through the growth arrest-specific 2 (Gas2)-related (GAR) domain. Heterozygous MACF1 missense variants affecting the zinc-binding residues in this domain result in a distinctive cortical and brain stem malformation.
View Article and Find Full Text PDFSurg Case Rep
September 2025
Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Kumamoto, Japan.
Introduction: Brain metastasis from gastric cancer is rare (0.5%) and often occurs with metastasis to other organs. We herein describe a very rare patient with a solitary brain metastasis from residual gastric cancer with no metastasis to other organs.
View Article and Find Full Text PDFBiol Psychol
September 2025
Institute of Brain and Psychological Sciences, Sichuan Normal University, Chengdu, 610066, China. Electronic address:
Working memory (WM) regulates information flow through gate mechanisms, consisting of four subprocesses: gate opening, gate closing, updating, and substitution. However, their neural mechanisms remain underexplored. While emotion-cognition interactions are well studied, the effects of negative mood on these subprocesses are unclear.
View Article and Find Full Text PDFEarly Hum Dev
August 2025
Department of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; Center for Molecular Medicine, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; National Health Commission (NHC) Key Lab
Objective: To synthesise current evidence on electroencephalography-based functional connectivity in preterm infants and clarify how prematurity alters early brain-network maturation.
Methods: A PRISMA-guided search (PubMed and Web of Science, inception-Mar 2025) identified 24 studies that quantified resting-state functional connectivity or graph-theory metrics in infants born <37 weeks' gestation. Study quality was rated with a six-item electroencephalography-functional connectivity checklist (reference montage, epoch length/number, artefact rejection, volume-conduction control, multiple-comparison correction).
Int J Exerc Sci
September 2025
School of Allied Health Professions, Louisiana State University Health Sciences Center at Shreveport, Shreveport, LA, USA.
Motion analysis is used to measure proper bicycle fit, avoid injury, and improve cycling performance. Small changes in position can impact joint kinematics and risk for overuse injury. Concerns regarding the often-used biomechanical model Plug-in-Gait (PIG) resulted in the creation of Conventional Gait Model 2 (CGM2).
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