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Background: Postoperative delirium (POD) is a common occurrence following orthopedic surgery, particularly in the older population. However, there is a relative scarcity of research on the use of intelligent algorithms to predict POD in older patients after orthopedic surgery. Therefore, the objective of this study was to evaluate the efficacy of ten distinct intelligent algorithms in predicting POD in older patients undergoing femoral neck fracture surgery.
Methods: This study selected ten advanced artificial intelligence algorithms to predict the occurrence of postoperative delirium by analyzing patient data.
Results: A total of 1889 patients were included in this study. The dataset for this study was divided into a training dataset, which consisted of synthetic data, and a testing dataset, representing real-world clinical scenarios. In the training dataset, we identified 267 cases of POD, accounting for 26.70% of the group. In the testing dataset, 172 cases of POD were confirmed, representing 19.35% of the group. Analysis using the Gradient Boosting Decision Tree (GBDT) algorithm revealed that age, preoperative hemoglobin levels, duration of anesthesia, and intraoperative blood loss are key predictive factors for POD in older patients with femoral neck fractures. Among the intelligent algorithms tested for predicting POD in the testing group, logistic regression, random forest, and the Multilayer Perceptron Classifier (MLPC) performed best with accuracy rates of 0.810, 0.810, and 0.808, respectively. In terms of precision, MLPC led with a score of 1.000, followed by random forest (0.714) and logistic regression (0.548). The highest recall rates were achieved by Gaussian Naive Bayes (gnb, 0.337) and AdaBoost (adab, 0.198). Gaussian Naive Bayes also performed best in F1 score (0.244). In the evaluation of the Area Under the Curve (AUC), logistic regression, MLPC, and XGBoost (XGB) demonstrated the best performance, with values of 0.669, 0.669, and 0.652, respectively.
Conclusions: The results of this study indicate that the Multilayer Perceptron Classifier (MLPC) algorithm performed the most excellently in predicting POD after femoral neck fracture surgery in older adults, with an accuracy rate reaching 80.8%. These findings suggest that machine learning algorithms, particularly MLPC, have significant potential and practical effectiveness in predicting POD in specific older patient populations.
Supplementary Information: The online version contains supplementary material available at 10.1186/s12883-025-04389-w.
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http://dx.doi.org/10.1186/s12883-025-04389-w | DOI Listing |
Bone Jt Open
September 2025
School of Medicine, University of Nottingham, Nottingham, UK.
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View Article and Find Full Text PDFJ Bone Miner Res
September 2025
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Autosomal Dominant Osteopetrosis (ADO) is a rare, osteosclerotic disorder usually caused by missense variants in the CLCN7 gene, resulting in impaired osteoclastic bone resorption. Penetrance is incomplete and disease severity varies widely, even among relatives within the same family. Although ADO can cause visual loss, osteonecrosis, osteomyelitis, and bone marrow failure, the most common complication of ADO is fracture.
View Article and Find Full Text PDFCalcif Tissue Int
September 2025
Department of Physical Education, Center for Health and Sports Sciences, Santa Catarina State University, Rua Pascoal Simone, 358, Coqueiros, Florianópolis, State of Santa Catarina, CEP: 88080-350, Brazil.
This study investigated the association between energy and macronutrient intake and bone health in 63 adolescents of both sexes who participated in volleyball, track and field, or swimming. Bone mineral content (BMC) and density (BMD) of the total body less head (TBLH), lumbar spine (L1-L4), and femoral neck were assessed using DXA. Bone geometry parameters, including cross-sectional area (CSA), cross-sectional moment of inertia (CSMI), and section modulus, were estimated.
View Article and Find Full Text PDFJ Arthroplasty
September 2025
Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, P. R. China; Shanghai Engineering Research Center for Orthopaedic Material Innovation and Tissue Regeneration, Shanghai, 201306, P. R. China. Electronic addre
Background: Heterotopic ossification (HO) is a common complication following hip arthroplasty that can limit hip range of motion (ROM). Oral direct factor Xa (FXa) inhibitors are commonly used anticoagulants after arthroplasty; however, they have a high risk of local bleeding and hematoma formation, which are significant triggers for HO formation. To our knowledge, there is no evidence regarding whether FXa inhibitors will increase HO incidence following hip arthroplasty.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
August 2025
From the Department of Orthopedic Surgery (Kuttner), Ohio State University, Columbus, OH, the Department of Orthopedic Surgery (Cancio-Bello, Thompson, Sems, Cross, Hidden, Yuan), Mayo Clinic, Rochester, MN, and the Biomechanics Laboratory (Fitzsimmons, Berglund), Department of Orthopedic Surgery, M
Objectives: The Femoral Neck System (FNS) is a fixed-angle side plate device approved for use in fixation of femoral neck fractures. The FNS perforates the lateral cortex of the subtrochanteric femur, which may increase the risk of postoperative subtrochanteric fractures compared with the inverted triangle cannulated screw (CS) construct. The purpose of this biomechanical study was to compare forces required to create subtrochanteric fractures in FNS and CS constructs in a synthetic bone biomechanical model.
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