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http://dx.doi.org/10.1016/j.crfs.2025.101165 | DOI Listing |
Food Chem
September 2025
Jiaxing Institute of Future Food, Jiaxing 314050, China; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. Electronic address:
This paper aims to explore the feasibility of enhancing the printing performance of 3D-printed meat analogues by varying the substitution amount of camellia seed cake protein (SCP) in the edible ink system based on proteins and polysaccharides. It covers the ink formulation, rheological properties and product analysis. The addition of SCP can significantly enhance the apparent viscosity, mechanical strength, and water retention capacity of the inks.
View Article and Find Full Text PDFInt J Pharm
September 2025
Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia Universidade Federal do Rio Grande do Sul, Avenida Ipiranga, 2752, Porto Alegre, Rio Grande do Sul 90610-000, Brazil; Laboratório de Nanocarreadores e Impressão 3D em Tecnologia Farmacêutica (Nano3D), Faculdade de Fa
The implementation of 3D printing technologies in clinical settings depends on formulations that are not only printable and compliant with quality standards but also physicochemical stable and reliable under real-use conditions. This study evaluated the in-use and long-term physicochemical and rheological stability of two hydrogel inks developed for semisolid extrusion (SSE) 3D printing: one containing pimobendan (PBD) and the other a placebo. PBD is a poorly water-soluble drug used to treat canine heart failure, whose formulation challenges highlight the potential of personalised drug delivery.
View Article and Find Full Text PDFACS Nano
September 2025
MOE Key Laboratory of Bio-Intelligent Manufacturing, Dalian Key Laboratory of Artificial Organ and Regenerative Medicine, School of Bioengineering, Dalian University of Technology, Dalian 116024, China.
3D printing of ceramics or glass typically requires sacrificial organic plasticizers and high-temperature sintering, which is time- and cost-consuming, potentially cytotoxic, and may compromise the bioactivity and functionality of the inorganic components. We herein developed purely inorganic self-healing colloidal gels, consisting of electrostatically attractive silica-based hard nanospheres, to enable 3D printing of highly strong inorganic constructs via additive-free and low temperature sintering (LTS) processing. Through cross-scale analysis of the structural and mechanical features, we quantitatively described the constitutive relationship of attractive colloidal gels based on the integration of colloidal assembly theory with experimental characterizations.
View Article and Find Full Text PDFNature
September 2025
Department of Orthopaedics, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.
We introduce Generative, Adaptive, Context-Aware 3D Printing (GRACE), a new approach combining 3D imaging, computer vision and parametric modelling to create tailored, context-aware geometries using volumetric additive manufacturing. GRACE rapidly and automatically generates complex structures capable of conforming directly around features ranging from cellular to macroscopic scales with minimal user intervention. Here we demonstrate its versatility in applications ranging from synthetic objects to biofabrication, including adaptive vascular-like geometries around cell-laden bioinks, resulting in improved functionality.
View Article and Find Full Text PDFACS Biomater Sci Eng
September 2025
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida 32611-6250, United States.
The development of thick, permeable, three-dimensional (3D) constructs is essential for advancing tissue engineering applications that require efficient mass transport and prolonged cell viability. In this study, a printable gelatin composite-poly(vinyl alcohol) (PVA) bioink is designed and evaluated for the self-supported fabrication of 3D thick porous constructs with satisfactory permeability. The proposed bioink incorporates gelatin solution, gelatin microgels, and PVA, which is utilized as a sacrificial porogen to facilitate postprinting pore formation.
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