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Background: Cesarean scar pregnancy (CSP) is an uncommon and potentially life-threatening form of ectopic pregnancy characterized by embryo implantation within the scar tissue of a prior cesarean delivery.
Objective: The aim of this study is to compare clinical outcomes between focused ultrasound ablation surgery (FUAS) combined with suction curettage under hysteroscopic guidance and transvaginal debridement and repair surgery (TDRS) in the treatment of CSP.
Methods: A retrospective analysis was conducted on 78 patients with CSP and treated between 2017 and 2023. Among them, 25 received FUAS followed by hysteroscopic suction curettage, and 53 underwent TDRS. Key clinical indicators included intraoperative parameters, postoperative recovery, treatment costs, complications, and subsequent pregnancy outcomes.
Results: No significant differences were observed between the two groups in terms of intraoperative blood loss, decline rates of β-human chorionic gonadotropin and hemoglobin, or menstrual recovery. FUAS was associated with a significantly shorter operative time (34.96 ± 28.90 vs 60.13 ± 22.87 minutes, <0.001), but also with a longer hospital stay (7.92 ± 2.98 vs 5.38 ± 1.61 days, < 0.001) and higher treatment costs (Ren Min Bi (RMB) 15,278 ± 3980 vs RMB 9443 ± 1570, <0.001). The treatment success rate was 76.00% for FUAS and 96.23% for TDRS (=0.078). Among patients seeking fertility, post-treatment pregnancy rates were 71.43% in the FUAS group and 76.47% in the TDRS group ( > 0.05). No procedure-related complications were reported in either group.
Conclusion: Both FUAS combined with curettage and TDRS demonstrated safety and effectiveness in the treatment of CSP, with favorable post-treatment fertility outcomes. TDRS was associated with shorter hospitalization and lower medical costs and may be preferable for certain CSP subtypes, such as type III. Treatment selection should be individualized based on clinical characteristics.
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http://dx.doi.org/10.2147/IJWH.S536488 | DOI Listing |
IEEE J Biomed Health Inform
September 2025
The Segment Anything Model (SAM) has attracted considerable attention due to its impressive performance and demonstrates potential in medical image segmentation. Compared to SAM's native point and bounding box prompts, text prompts offer a simpler and more efficient alternative in the medical field, yet this approach remains relatively underexplored. In this paper, we propose a SAM-based framework that integrates a pre-trained vision-language model to generate referring prompts, with SAM handling the segmentation task.
View Article and Find Full Text PDFEur J Neurol
September 2025
Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background: Frontotemporal dementia (FTD) encompasses diverse clinical phenotypes, primarily characterized by behavioral and/or language dysfunction. A newly characterized variant, semantic behavioral variant FTD (sbvFTD), exhibits predominant right temporal atrophy with features bridging behavioral variant FTD (bvFTD) and semantic variant primary progressive aphasia (svPPA). This study investigates the longitudinal structural MRI correlates of these FTD variants, focusing on cortical and subcortical structural damage to aid differential diagnosis and prognosis.
View Article and Find Full Text PDFCardiovasc Ther
September 2025
Department of Cardiology, Tianjin University Chest Hospital, Tianjin, China.
Hypertension constitutes a major risk factor for cardiovascular diseases. Globally, the management and control of hypertension remain suboptimal. At present, pharmacological intervention is a critical strategy for patients with hypertension to achieve blood pressure regulation.
View Article and Find Full Text PDFJ Acute Med
September 2025
Rush University Medical Center Department of Emergency Medicine Chicago, IL USA.
Cardiac arrest is a common condition with low survival rates. Point-of-care ultrasound (POCUS) has been increasingly integrated in cardiac arrest care to enhance diagnostic accuracy and guide interventions. POCUS can be divided into cardiac and non-cardiac applications.
View Article and Find Full Text PDFDose Response
September 2025
Department of Interventional Radiology, The Second People's Hospital of Nantong, Nantong, Jiangsu Province, China.
Objectives: This study investigated the cardioprotective effects of stachydrine (STA) in lipopolysaccharide (LPS)-induced septic mice and H9c2 cardiomyocytes, focusing on its anti-apoptotic, anti-inflammatory, and anti-ferroptotic actions.
Methods: We established an LPS-induced sepsis model in mice and an LPS-stimulated H9c2 cardiomyocyte model in vitro.
Results: STA markedly reduced LPS-induced myocardial apoptosis, as demonstrated by decreased TUNEL-positive cells, and attenuated the elevation of serum cardiac injury markers, including creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), brain natriuretic peptide (BNP), cardiac troponin I (cTnI), and cardiac troponin T (cTnT) levels.