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Spatiotemporal analysis and monitoring of socially unequally distributed environmental hazards and resources as well as their effects on health provide an important basis for political decisions under environmental justice aspects. Appropriate analysis and monitoring approaches are accompanied by diverse conceptual and methodological challenges, which are described and discussed in this paper.A major challenge lies in the comprehensive modeling of environmental exposures, as measurement data are often only selectively available, requiring complex interpolation methods. Further challenges lie in quantifying inequalities in environmental exposures, as environmental and social data are usually only available in aggregate form at the level of administrative spatial units, and in the lack of data on subjective assessment of the quality of environmental exposures. Specific challenges to large-scale, Europe-wide monitoring of health-relevant environmental inequalities by the World Health Organization (WHO) arise from a lack of information on relevant environmental exposures or inequality dimensions, different types of data, and a lack of quantification of social differences in vulnerability. This currently limits the ability to make statements about the social distribution of environmental exposures in the European Region and their health effects.In order to make informed political decisions and reduce socially unequally distributed environmental burdens and resources as well as their health effects in an evidence-based manner, a substantial improvement regarding data availability is necessary as a prerequisite for a comprehensive, standardized monitoring.
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http://dx.doi.org/10.1007/s00103-025-04118-1 | DOI Listing |
Photochem Photobiol Sci
September 2025
Department of Genetics and Plant Breeding, C. P. College of Agriculture, S. D. Agricultural University, Sardarkrushinagar, 385506, India.
The electromobility shift assay (EMSA) is a popular and productive molecular biology tool for studying protein-nucleic acid interactions. EMSA is a technique applied to the revelation of the binding dynamics of proteins, like transcription factors, to DNA or RNA. There are ample essential phases in the technique.
View Article and Find Full Text PDFNature
September 2025
State Key Joint Laboratory of Environmental Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing, China.
Smoke from extreme wildfires in Canada adversely affected air quality in many regions in 2023. Here we use satellite observations, machine learning and a chemical transport model to quantify global and regional PM (particulate matter less than 2.5 μm in diameter) exposure and human health impacts related to the 2023 Canadian wildfires.
View Article and Find Full Text PDFEnviron Sci Technol
September 2025
State Key Laboratory of Advanced Environmental Technology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
The potential of PM to cause lung cancer has been well established; however, evidence regarding which specific components are responsible remains limited. We investigated dissolved organic matter (DOM) in PM using high-resolution mass spectrometry (HRMS) and cellular DNA damage assays to elucidate molecular composition and sources of carcinogenic components. Our analysis revealed hundreds of genotoxic compounds, with condensed aromatic amines predominating in number, abundance, and contribution to overall genotoxicity.
View Article and Find Full Text PDFAlcohol Clin Exp Res (Hoboken)
September 2025
Department of Neuroscience and Experimental Therapeutics, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Background: Prenatal alcohol exposure (PAE) causes fetal alcohol spectrum disorder (FASD) and is associated with various cognitive and sensory impairments, including olfactory dysfunction. While both genetic and environmental factors contribute to olfactory dysfunction, PAE is considered a significant factor affecting brain development, including the olfactory system. In this study, we investigated the impact of PAE on the developing olfactory bulb (OB), specifically focusing on OB RGCs-radial glial cells that give rise to OB projection neurons.
View Article and Find Full Text PDFPhysiol Rep
September 2025
Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
This study investigated the effects of fermentable fiber and polyphenol supplementation on mood and cognition following rapid ascent to simulated 4300 m. Healthy adults (n = 13, 21 ± 3 years) participated in a randomized, placebo-controlled crossover study consisting of three, 2-week phases separated by ≥1 week. Food products containing the fiber and polyphenol supplement or placebo were consumed during each phase.
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