98%
921
2 minutes
20
Background: This study developed and tested a multi-dimensional model for evaluating the severity of temporomandibular disorders (TMDs) based on the five core symptoms (5Ts) of the Diagnostic Criteria for TMDs (DC/TMD).
Methods: Study participants were sourced from a university hospital. The 5Ts screener was expanded to include the dimensions of duration, frequency, intensity, and interference with daily activities (5Ts-4D). The 5Ts-4D, along with the Graded Chronic Pain Scale (GCPS), Jaw Functional Limitation Scale-8 (JFLS-8), and Oral Health Impact Profile for TMDs (OHIP-TMD), was administered to individuals with no (NT), intra-articular (IT), pain-related (PT), and combined (CT) TMDs as determined using the DC/TMD methodology and diagnostic algorithms. Reliability and validity testing were carried out thereafter (α = 0.05).
Results: Among the 324 participants, 13.6% had NT, while 42.9%, 15.7%, and 27.8% were diagnosed with IT, PT, and CT, respectively. The 5Ts-4D demonstrated good internal consistency (Cronbach's alpha = 0.83-0.95) and moderate-to-good test-retest reliability (ICC = 0.51-0.97) across various symptom-dimension combinations. It also showed robust known-group differences (PT, CT, IT>NT) and convergent validity, with strong correlations between global TMD severity, JFLS-8, and OHIP-TMD (r = 0.68-0.78).
Conclusions: The 5Ts-4D, with its strong reliability and robust validity, holds promise as a straightforward tool for evaluating TMD symptoms and severity, thereby contributing to more effective management of TMD patients.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/jop.70050 | DOI Listing |
Oral Surg Oral Med Oral Pathol Oral Radiol
July 2025
Department of Orofacial Pain and TMJ Disorders, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA. Electronic address:
Objective: This systematic review aimed to evaluate and compare the analgesic efficacy of intra-articular morphine versus other agents in managing arthrogenic TMJ disorders.
Study Design: The review adhered to PRISMA guidelines and was registered in PROSPERO (CRD420251011088). A comprehensive search was conducted across PubMed, EMBASE, Scopus, Web of Science, and OVID for randomized controlled trials (RCTs) published up to March 2025.
Br J Oral Maxillofac Surg
July 2025
Department of Oral and Maxillofacial Surgery, Hospital Clínico Universitario San Carlos, Calle del Prof Martín Lagos, s/n, 28040 Madrid, Spain.
This study aimed to evaluate the long-term effectiveness of arthroscopic discopexy using resorbable pins in the treatment of temporomandibular joint (TMJ) disc displacement over a 10-year follow-up period. A retrospective analysis was conducted on thirty-three patients who underwent arthroscopic discopexy with resorbable pins between January 2007 and November 2013. Clinical outcomes, including maximal interincisal opening (MIO), lateral movements (LM), protrusive movement (PM), joint pain with the visual analogue scale (VAS), joint locking, and clicking; were assessed at one, three, and six months and at 1.
View Article and Find Full Text PDFJ Adv Res
September 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of Oral Anatomy and Physiology and TMD, School of Stomatology, The Fourth Military Medical Univ
Introduction: Aberrant biomechanical force-induced chondrocyte adipogenesis is involved in the development of temporomandibular joint osteoarthritis (TMJ OA). Growth differentiation factor 11 (GDF11) has been implicated in this process. However, whether mechanosensitive histone deacetylase 3 (HDAC3) regulates GDF11 signaling in the context of TMJ OA remains to be elucidated.
View Article and Find Full Text PDFBr J Oral Maxillofac Surg
August 2025
University Hospital of Southern Denmark, Esbjerg, 3D Lab Denmark, Finsensgade 35, 6700 Esbjerg, Denmark; University Hospital of Southern Denmark, Esbjerg, Department of Oral and Maxillofacial Surgery, Finsensgade 35, 6700 Esbjerg, Denmark; University of Southern Denmark, Faculty of Health Sciences,
Limited long-term 3-dimensional (3D) studies exist evaluating risk factors for condylar resorption following orthognathic surgery. Our aim was to evaluate patient demographics, clinical and radiographic characteristics, and orthognathic surgical effects on long-term postoperative condylar volume and height, and horizontal skeletal stability, using a 3D approach. Analysis of clinical data and cone-beam computed tomography before, and approximately two weeks and five years after surgery was carried out on 50 subjects (17 male, 33 female), mean (range) age 25.
View Article and Find Full Text PDFFASEB Bioadv
August 2025
Laboratory of Molecular Signaling and Stem Cells Therapy, Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction Beijing Stomatological Hospital, School of Stomatology, Capital Medical University Beijing China.
Previous studies reported the pro-osteogenic ability of L-Tryptophan (L-Trp) and Calcium-Sensing RCeceptor (CaSR) respectively. Recent researchers found L-Trp could activate CaSR. Therefore, this study investigated the osteogenic mechanisms of L-Trp through CaSR activation.
View Article and Find Full Text PDF