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Landfills serve both as essential infrastructure for solid waste disposal and as potential sources of significant environmental risk. Leachate leakage has become a global concern due to its adverse impact on groundwater quality and associated public health threats. Accurate assessment of concealed leakage and its uncertainty is critical for effective risk management. However, traditional analytical-Monte Carlo coupled methods often fail to capture the complexity of leakage-related uncertainties and are computationally expensive. To address these challenges, we propose an Active Learning-enhanced Deep Neural Network (AL-DNN) model. This surrogate model is constructed based on datasets generated by a high-performance Groundwater Simulation Numerical Model (GSNM), providing a computationally efficient alternative for simulating contaminant transport. Firstly, a deep neural network is used to replicate simulation results of groundwater contamination under uncertain parameters. Secondly, an active learning strategy is introduced to identify and select informative samples, improving prediction accuracy while minimizing the number of required labeled data. Results show that the AL-DNN model achieves comparable accuracy to traditional methods using only 60 samples, leading to a 90 % reduction in computation time. Finally, the model is applied to a simulated landfill leakage scenario to predict COD concentration distributions and assess contamination risks. The results indicate a maximum exceedance probability of 0.76 at Monitoring Well 1. These findings highlight the effectiveness and practicality of the proposed method in supporting rapid, reliable groundwater contamination risk assessments under uncertainty.
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http://dx.doi.org/10.1016/j.jhazmat.2025.139556 | DOI Listing |
J Oral Biol Craniofac Res
August 2025
Neura Integrasi Solusi, Jl. Kebun Raya No. 73, Rejowinangun, Kotagede, Yogyakarta, 55171, Indonesia.
Background: Periodontal disease is an inflammatory condition causing chronic damage to the tooth-supporting connective tissues, leading to tooth loss in adults. Diagnosing periodontitis requires clinical and radiographic examinations, with panoramic radiographs crucial in identifying and assessing its severity and staging. Convolutional Neural Networks (CNNs), a deep learning method for visual data analysis, and Dense Convolutional Networks (DenseNet), which utilize direct feed-forward connections between layers, enable high-performance computer vision tasks with reduced computational demands.
View Article and Find Full Text PDFFront Genet
August 2025
Hunan Provincial Key Laboratory of Finance and Economics Big Data Science and Technology, Hunan University of Finance and Economics, Changsha, China.
RNA N4-acetylcytidine (ac4C) is a crucial chemical modification involved in various biological processes, influencing RNA properties and functions. Accurate prediction of RNA ac4C sites is essential for understanding the roles of RNA molecules in gene expression and cellular regulation. While existing methods have made progress in ac4C site prediction, they still struggle with limited accuracy and generalization.
View Article and Find Full Text PDFFront Vet Sci
August 2025
Pathobiology and Population Science, Royal Veterinary College, Hatfield, United Kingdom.
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma (NHL) in humans, accounting for about 30-40% of NHL cases worldwide. Canine diffuse large B-cell lymphoma (cDLBCL) is the most common lymphoma subtype in dogs and demonstrates an aggressive biologic behaviour. For tissue biopsies, current confirmatory diagnostic approaches for enlarged lymph nodes rely on expert histopathological assessment, which is time-consuming and requires specialist expertise.
View Article and Find Full Text PDFVet World
July 2025
Department of Veterinary Science, Faculty of Veterinary Medicine, Rajamangala University of Technology Tawan-OK, Chonburi, Thailand.
Background And Aim: Granulosa cells (GCs) are crucial mediators of follicular development and oocyte competence in goats, with their gene expression profiles serving as potential biomarkers of fertility. However, the lack of a standardized, quantifiable method to assess GC quality using transcriptomic data has limited the translation of such findings into reproductive applications. This study aimed to develop a hybrid deep learning model integrating one-dimensional convolutional neural networks (1DCNNs) and gated recurrent units (GRUs) to classify GCs as fertility-supporting (FS) or non-fertility-supporting (NFS) using single-cell RNA sequencing (scRNA-seq) data.
View Article and Find Full Text PDFMed Phys
September 2025
School of Computer, Electronics and Information, Guangxi University, Nanning, China.
Background: Deformable medical image registration is a critical task in medical imaging-assisted diagnosis and treatment. In recent years, medical image registration methods based on deep learning have made significant success by leveraging prior knowledge, and the registration accuracy and computational efficiency have been greatly improved. Models based on Transformers have achieved better performance than convolutional neural network methods (ConvNet) in image registration.
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