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The patient (male, two expert reports: 61 and 63 years old) experienced symptoms of a flu-like infection with rapid deterioration and cognitive complaints. He has been an employee of the municipal building yard with a sewage treatment plant for approximately 24 years.Acute renal insufficiency (creatinine 9.7 mg/dl), increased anti-Leptospira IgM antibodies and Leptospira DNA using PCR were detected. The CT neurocranium without contrast medium did not reveal any relevant abnormalities.Sepsis with multiorgan failure including a type 2 myocardial infarction and acute renal failure in the context of leptospirosis was diagnosed.Antibiotic therapies with piperacillin/tazobactam, clarithromycin and meropenem were given. Regarding acute renal failure, renal function was significantly improved by using temporary hemodialysis. After an assessment, leptospirosis was recognized as occupational disease No. 3102 in accordance with Appendix 1 of the Occupational Diseases Ordinance.Physicians should take a work history and, if there is reasonable suspicion, are legally obliged to report suspected occupational diseases. The primary infection and such a complex course (including costs) can be prevented by adequate occupational safety.
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http://dx.doi.org/10.1055/a-2612-3357 | DOI Listing |
Trans R Soc Trop Med Hyg
September 2025
Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Virus sensing and signaling Unit, 75015 Paris, France.
Background: In 2023, Mayotte, a French department in the Mozambique channel, experienced a long drought that led to potable water restrictions. Although the French vaccination schedule makes polio vaccination compulsory for children, the large proportion of migrants on the island coupled with the water crisis raised concerns about the establishment of poliovirus transmission chains. Therefore, a surveillance was implemented to detect polioviruses in sewage sampled in the two main wastewater treatment plants.
View Article and Find Full Text PDFWater Res
August 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China. Electronic address:
Global phosphorus (P) resources are facing a depletion crisis, and pyrolysis of P-rich sewage sludge (SS) offers significant resource potential. Optimizing pyrolysis conditions remains key yet challenging for enhancing P retention and bioavailability. This study conducted a correlation-prediction-causation integrated framework (CPCIF) to investigate how heating temperature (HT), heating rate (HR), and retention time (RT) influence total P enrichment rate (BTPE), relative inorganic P transformation rate (BITP), and relative apatite P transformation rate (BAIP) from SS to biochar during pyrolysis.
View Article and Find Full Text PDFVirology
September 2025
Department of Microbiology, Faculty of Pharmacy, Ahram Canadian University (ACU), 6th October City, Giza, 12566, Egypt. Electronic address:
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) has recently become a serious cause for global concern because of non-susceptibility to multiple antimicrobial classes, its prevalence in nosocomial infections, and the lack of effective treatments against such a pathogen.
Methods: This study isolated two lytic phages from hospital sewage, purified, propagated, characterized morphologically by transmission electron microscopy, and genomically by Oxford Nanopore Sequencing. The phage lysates were then formulated individually as carboxymethylcellulose (CMC) 5 % w/v hydrogels.
Water Res
September 2025
Key Laboratory of Drinking Water Science and Technology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. Electronic address:
Flocculation is one of the most common treatment processes for sludge dewatering, representing the last line of solid-liquid separation for sludge dewatering. However, the macroscopic and descriptive theories of polyacrylamide (PAM) -based over-flocculation have limited the optimization of its performance in the dewatering of sewage sludge, whose water is typically trapped within a three-dimensional gel matrix governed by extracellular polymeric substances (EPS). This study focuses on loosely bound EPS (LB-EPS) to uncover molecular-level mechanism of excessive PAM dosing.
View Article and Find Full Text PDFMar Pollut Bull
September 2025
Department of Ocean Engineering, Pukyong National University, 45 Yongso-ro, Nam-Gu, Busan 48513, Republic of Korea. Electronic address:
Coastal sediments in semi-enclosed bays are particularly susceptible to contamination due to limited water circulation and ongoing contaminant input. In Masan Bay, a heavily impacted coastal area in Korea, sediment remediation is essential to alleviate the effects of organic enrichment and hypoxia. This study investigated the effectiveness of oyster shell capping as an in-situ remediation technique by assessing its impact on sediment environment, microbial communities, and macrobenthic fauna.
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