98%
921
2 minutes
20
Here, we present a model for calculating the mechanical power delivered by the metabolism while running in alpine settings. The aim is to quantify power for various conditions in trail and mountain running, using data from modern consumer sports watches and complementary acceleration sensors. After extending an existing analytical model by including collision losses, speed-dependent elastic energy storage, a force-rate contribution, and an additional power component accounting for upper-body movement, we generalize it to running uphill and downhill. We introduce additional power components to account for the increased metabolic work required to run on uneven technical sections. On flat terrain and when assuming an elasticity coefficient as motivated from the literature, our approach predicts a comparable output between cycling and running for athletes similarly trained in both disciplines. As for running uphill and downhill, we obtain a very good agreement with the measured metabolic cost. This corresponds to the first time an algebraic model explains this inclination dependency. We evaluate our model using data from an exemplary trail run recorded with a standard consumer setup. This work provides a transparent, physics-based model grounded in scientific principles, offering an interpretable, reproducible, and adaptable framework for estimating mechanical power across diverse trail running conditions.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jbiomech.2025.112892 | DOI Listing |
Crit Care Explor
September 2025
Division of Pulmonary, Allergy, Critical Care, and Sleep, University of Minnesota, Minneapolis, MN.
Mean airway pressure, a monitored variable continuously available on the modern ventilator, is the pressure measured at the airway opening averaged over the time needed to complete the entire respiratory cycle. Mean airway pressure is well recognized to connect three key physiologic processes in mechanical ventilation: physical stretch, cardiovascular dynamics, and pulmonary gas exchange. Although other parameters currently employed in adults to determine "safe" ventilation are undoubtedly valuable for daily practice, all have limitations for continuous monitoring of ventilation hazard.
View Article and Find Full Text PDFRSC Adv
September 2025
School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 211816 China
Diabetic wounds present persistent challenges due to impaired healing, recurrent infection, oxidative stress, and dysregulated glucose metabolism. Bioinspired polymeric microneedle (MN) patches have emerged as multifunctional platforms capable of penetrating the stratum corneum to deliver therapeutics directly into the dermis, enabling glucose regulation, antimicrobial action, reactive oxygen species (ROS) modulation, and proangiogenic stimulation. Recent experimental evidence has demonstrated that the integration of glucose oxidase-loaded porous metal-organic frameworks, photothermal nanomaterials, and antioxidant hydrogels within dissolvable MNs achieves synergistic bactericidal effects, accelerates collagen deposition, and enhances neovascularization in diabetic wound models.
View Article and Find Full Text PDFAdv Mater
September 2025
Department of Materials Science and Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, 999077, P. R. China.
Alkaline zinc-iron flow batteries (AZIFBs) are one of the promising aqueous redox chemistries for large-scale energy storage due to their intrinsic safety and low cost. However, the energy efficiency (EE) and power density of batteries with low-cost polybenzimidazole (PBI) membranes are still limited due to the relatively poor ionic conductivity of PBI in an alkaline medium. Here, this study proposes a novel chemical approach for regulating the chemical environment of the PBI membrane.
View Article and Find Full Text PDFJ Intensive Care
September 2025
German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universitat (LMU), University Hospital Grosshadern, Munich, Germany.
Background: Survivors of critical illness frequently face physical, cognitive and psychological impairments after intensive care. Sensorimotor impairments potentially have a negative impact on participation. However, comprehensive understanding of sensorimotor recovery and participation in survivors of critical illness is limited.
View Article and Find Full Text PDFNanomicro Lett
September 2025
Department of Mechanical, Aerospace & Biomedical Engineering, University of Tennessee, Knoxville, Knoxville, TN, 37996, USA.
3D printing, as a versatile additive manufacturing technique, offers high design flexibility, rapid prototyping, minimal material waste, and the capability to fabricate complex, customized geometries. These attributes make it particularly well-suited for low-temperature hydrogen electrochemical conversion devices-specifically, proton exchange membrane fuel cells, proton exchange membrane electrolyzer cells, anion exchange membrane electrolyzer cells, and alkaline electrolyzers-which demand finely structured components such as catalyst layers, gas diffusion layers, electrodes, porous transport layers, and bipolar plates. This review provides a focused and critical summary of the current progress in applying 3D printing technologies to these key components.
View Article and Find Full Text PDF