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Recent advancements in emerging technologies such as IoT and AI have driven digital innovation, while also accelerating the sophistication of cyberattacks and expanding the attack surface. In particular, inter-state cyber warfare, sophisticated ransomware threats, and insider-led personal data breaches have emerged as significant new security risks. In response, this study proposes a Privacy-Aware Integrated Log System model developed to mitigate diverse security threats. By analyzing logs generated from personal information processing systems and security systems, integrated scenarios were derived. These scenarios are designed to defend against various threats, including insider attempts to leak personal data and the evasion of security systems, enabling scenario-based contextual analysis that goes beyond simple event-driven detection. Furthermore, the Analytic Hierarchy Process (AHP) was applied to quantitatively assess the relative importance of each scenario, demonstrating the model's practical applicability. This approach supports early identification and effective response to personal data breaches, particularly when time and resources are limited by focusing on the top-ranked scenarios based on relative importance. Therefore, this study is significant in that it goes beyond fragmented log analysis to establish a privacy-oriented integrated log system from a holistic perspective, and it further validates its operational efficiency in field applications by conducting an AHP-based relative importance evaluation.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12389991 | PMC |
http://dx.doi.org/10.3390/s25165181 | DOI Listing |
Background: The study aimed to adapt a stress and well-being intervention delivered via a mobile health (mHealth) app for Latinx Millennial caregivers. This demographic, born between 1981 and 1996, represents a significant portion of caregivers in the United States, with unique challenges due to higher mental distress and poorer physical health compared to non-caregivers. Latinx Millennial caregivers face additional barriers, including higher uninsured rates and increased caregiving burdens.
View Article and Find Full Text PDFNeurol Res
September 2025
Henan Provincial People's Hospital, Department of Surgery of Spine and Spinal Cord, People's Hospital of Zhengzhou University, Zhengzhou, China.
Background: Immunotherapy holds significant yet underexplored potential for low-grade glioma (LGG) treatment. We therefore interrogated the role of Fanconi Anemia Complementation Group C (FANCC) as a novel immune checkpoint regulator given its spatial correlation with tumor microenvironments and clinical associations with immunosuppressive markers.
Objectives: FANCC is implicated in various tumor progressions; its role in LGG remains unexplored.
ACS Nano
September 2025
State Key Laboratory of Materials-Oriented Chemical Engineering, National Engineering Research Center for Special Separation Membrane, Nanjing Tech University, Nanjing 210009, China.
Airborne pathogens and pollution control typically necessitate multiple membranes, each specializing in efficient aerosol filtration, moisture regulation, or antimicrobial protection. Integrating all these functions into a single membrane is highly advantageous but remains inherently challenging due to material incompatibility and inevitable performance trade-offs. Here, we present a photoactive Janus nanofibrous membrane for highly efficient air purification, engineered via sequential electrospinning.
View Article and Find Full Text PDFGenet Med
September 2025
Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, Fulham Road, London, UK. Electronic address:
Purpose: Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare cancer susceptibility syndrome exclusively attributable to pathogenic variants in FH (HGNC:3700). This paper quantitatively weights the phenotypic context (PP4/PS4) of such very rare variants in FH.
Methods: We collated clinical diagnostic testing data on germline FH variants from 387 individuals with HLRCC and 1,780 individuals with renal cancer, and compared the frequency of 'very rare' variants in each phenotypic cohort against 562,295 population controls.
Anal Chim Acta
November 2025
HIV-1 Molecular Epidemiology Laboratory, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Microbiology Department, Hospital Universitario Ramón y Cajal, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, 28034, Spain. Electronic address:
Background: Currently, 39.9 million people are infected with the human immunodeficiency virus (HIV), and 1.3 million new infections occur annually, with over 170 circulating variants.
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