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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12390766 | PMC |
| http://dx.doi.org/10.1002/ctm2.70463 | DOI Listing |
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For a long time neglected, the mpox virus has caused two public health emergency declarations by the World Health Organization in just two years. Rapid detection and characterization of the viral strains involved are crucial for better control of the disease. Recent work on viral genome sequencing in the Democratic Republic of the Congo (DRC) has shown the emergence in 2023 of clade Ib, with sustained human-to-human transmission and rapid spread to several other non-endemic neighboring countries, as well as outside Africa.
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Cytochrome P450 enzymes (P450s), particularly those of microbial origin, are highly versatile biocatalysts capable of catalyzing a broad range of regio- and stere-oselective reactions. P450s derived from extremophiles are of particular interest due to their potential tolerance to high temperature, salinity, and acidity. This study aimed to identify and classify novel microbial P450 enzymes from extreme environments across Türkiye, including hydrothermal springs, hypersaline lakes, and an acid-mine drainage site.
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Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Ecology and Environmental Science, Qingdao Marine Science and Technology Center, Qingdao 266237, China. Electronic address: jinxianliu@gmail
Determination of evolutionary mechanisms underlying innovative traits is crucial for understanding the vast diversity of species and phenotypes. Given their respiratory physiologies, fishes are compelling subjects for evolutionary analysis of the hemoprotein-based oxygen-transport systems. Asian noodlefishes (Osmeriformes: Salangidae) and Antarctic icefishes (Notothenioidei: Channichthyidae) are examples of fish clades that generally do not express myoglobin or hemoglobin.
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