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Purpose: This study compares the effectiveness and safety of a novel flexible and navigable suction (FANS) ureteral access sheath (UAS), utilizing a lower-power holmium laser (LPHL), against conventional UAS (cUAS) with a high-power holmium laser (HPHL) for retrograde intrarenal surgery (RIRS) in treating renal stones.
Materials And Methods: Patients aged 18 years and older undergoing RIRS for renal stones were enrolled, excluding those with uncontrolled urinary tract infections, simultaneous ureteral stones, radiolucent stones, and abnormal anatomy. The FANS-UAS group used an LPHL with fixed fragmentation setting, while the cUAS group used an HPHL for both dusting and fragmentation. Outcomes included stone-free status (SFS) rates on day 1, week 1, month 1, operative time, and complications.
Results: Seventy patients (41 males, 29 females) with a median age of 55.5 years underwent 34 cUAS and 36 FANS-UAS procedures. The complete stone-free rate in the FANS-UAS group was higher across all measured time points (63 %, 66.7 %, and 72.2 % at the first day, one week, and one month respectively) compared to the cUAS group (23.5 %, 35.2 %, and 50 %). Multivariable analysis confirmed that using FANS-UAS significantly increased the degree of SFS across these intervals. Furthermore, the FANS-UAS group had a significantly shorter mean operative time (60 ± 26.5 min) than the cUAS group (69.2 ± 30.1 min, p = 0.028). Both groups showed comparable complication rates and negligible serious adverse events.
Conclusion: RIRS with FANS-UAS demonstrated higher early SFS and shorter operative times compared to cUAS, offering efficiency and reduced dependency on HPHL with minimal complications.
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http://dx.doi.org/10.1016/j.jfma.2025.08.032 | DOI Listing |
J Formos Med Assoc
August 2025
Department of Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan; School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan. Electronic address:
Purpose: This study compares the effectiveness and safety of a novel flexible and navigable suction (FANS) ureteral access sheath (UAS), utilizing a lower-power holmium laser (LPHL), against conventional UAS (cUAS) with a high-power holmium laser (HPHL) for retrograde intrarenal surgery (RIRS) in treating renal stones.
Materials And Methods: Patients aged 18 years and older undergoing RIRS for renal stones were enrolled, excluding those with uncontrolled urinary tract infections, simultaneous ureteral stones, radiolucent stones, and abnormal anatomy. The FANS-UAS group used an LPHL with fixed fragmentation setting, while the cUAS group used an HPHL for both dusting and fragmentation.
Urol Case Rep
September 2025
St. Luke's Clinical Hospital, Chugunnaya str.,b.46, Saint-Petersburg, 195009, Russia.
Percutaneous nephrolithotomy is one of the modern methods for treating kidney stones larger 2 cm. When anticoagulation therapy cannot be stopped, retrograde intrarenal surgery (RIRS) is recommended. We report a case of RIRS using flexible and navigable suction ureteral access sheath (FANS-UAS) and Thulium fiber laser (TFL) in a patient with multiple large kidney stones who could not be stopped on anticoagulant therapy.
View Article and Find Full Text PDFArch Ital Urol Androl
June 2025
CDC Ambrosiana, Cesano Boscone (MI).
The formation of kidney stones is a complex biologic process involving interactions among genetic, anatomic, dietary, and environmental factors. Traditional lithogenic models were based on urine supersaturation in relation to the activity of crystallization promoters and inhibitors. However, modern research has added new principles such as the "renal epithelial cell response" and the role of inflammation and oxidative stress leading to the development of a "multi-hit hypothesis".
View Article and Find Full Text PDFBMC Urol
May 2025
Chengdu Second People's Hospital, No. 10, Qing Yun South Street, Chengdu, Sichuan, 610017, P.R. China.
Background: Traditional ureteral access sheaths (T-UAS) are limited by rigidity and lack of suction, potentially increasing complications. Flexible and navigable suction ureteral access sheaths (FANS-UAS) offer improved maneuverability and active suction, but comparative evidence on their efficacy and safety is scarce. This meta-analysis evaluates FANS-UAS versus T-UAS in flexible ureteroscopy (fURS).
View Article and Find Full Text PDFBMC Urol
May 2025
Urology Section , Department of Surgery, Hazm Mebaireek General Hospital, Hamad Medical Corporation, Doha, Qatar.
Objectives: Flexible ureteroscopy (FURS) is a commonly chosen technique for kidney stone treatment. The use of ureteral access sheaths (UAS) enhances both access and the procedure's effectiveness. This study performs a systematic review and meta-analysis to assess the efficacy and safety of flexible and navigable suction UAS (FANS-UAS) versus standard UAS (S-UAS) in FURS.
View Article and Find Full Text PDF