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Layout plays a crucial role in graphic design and poster generation. Recently, the application of deep learning models for layout generation has gained significant attention. This paper focuses on using a GAN-based model conditioned on images to generate advertising poster graphic layouts, requiring a dataset of paired product images and layouts. To address this task, we introduce the Content-aware Graphic Layout Dataset (CGL-Dataset), consisting of 60,548 paired inpainted posters with annotations and 121,000 clean product images. The inpainting artifacts introduce a domain gap between the inpainted posters and clean images. To bridge this gap, we design two GAN-based models. The first model, CGL-GAN, uses Gaussian blur on the inpainted regions to generate layouts. The second model combines unsupervised domain adaptation by introducing a GAN with a pixel-level discriminator (PD), abbreviated as PDA-GAN, to generate image-aware layouts based on the visual texture of input images. The PD is connected to shallow-level feature maps and computes the GAN loss for each input-image pixel. Additionally, we propose three novel content-aware metrics to assess the model's ability to capture the intricate relationships between graphic elements and image content. Quantitative and qualitative evaluations demonstrate that PDA-GAN achieves state-of-the-art performance and generates high-quality image-aware layouts.
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http://dx.doi.org/10.1109/TPAMI.2025.3602846 | DOI Listing |
Acc Chem Res
September 2025
Department of Chemistry, FRQNT Centre for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street W, Montréal, Québec H3A 0B8, Canada.
ConspectusMolecular photochemistry, by harnessing the excited states of organic molecules, provides a platform fundamentally distinct from thermochemistry for generating reactive open-shell or spin-active species under mild conditions. Among its diverse applications, the resurgence of the Minisci-type reaction, a transformation historically reliant on thermally initiated radical conditions, has been fueled by modern photochemical strategies with improved efficiency and selectivity. Consequently, the photochemical Minisci-type reaction ranks among the most enabling methods for C()-H functionalizations of heteroarenes, which are of particular significance in medicinal chemistry for the rapid diversification of bioactive scaffolds.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, P. R. China.
The COVID-19 pandemic remains a global health crisis, with successive SARS-CoV-2 variants exhibiting enhanced transmissibility and immune evasion. Notably, the Omicron variant harbors extensive mutations in the spike protein's receptor-binding domain (RBD), altering viral fitness. While temperature is a critical environmental factor modulating viral stability and transmission, its molecular-level effects on variant-specific RBD-human angiotensin-converting enzyme 2 (hACE2) interactions remain underexplored.
View Article and Find Full Text PDFJMIR Public Health Surveill
August 2025
College of Design and Engineering, National University of Singapore, Singapore, Singapore.
Background: The COVID-19 lockdowns led to significant resource constraints, potentially impacting mental health and decision-making behaviors. Understanding the psychological and behavioral consequences could inform designing interventions to mitigate the negative impacts of episodic scarcity during crises like pandemics.
Objective: To investigate the effects of perceived scarcity on mental health (stress and fear), cognitive functioning, time and risk preferences (present bias and risk aversion), and trade-offs between groceries, health, and temptation goods during and after the COVID-19 lockdown in Shanghai.
J Child Psychol Psychiatry
September 2025
Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Background: Prospective studies of autism family history infants primarily report recurrence and predictors of autism at 3 years. Less is known about ADHD family history infants and later childhood outcomes. We characterise profiles of mid-childhood developmental and behavioural outcomes in infants with a family history of autism and/or ADHD to identify potential support needs and patterns of co-occurrence across domains.
View Article and Find Full Text PDFTrauma Surg Acute Care Open
September 2025
UCHealth, Loveland, Colorado, USA.
Introduction: Trauma clinical guidance (guidelines, protocols, algorithms, etc) has been shown to improve patient outcomes; however, it is only used in about half of the patients to whom it applies. Guidance implementation is affected by intrinsic factors (eg, guidance format) as well as extrinsic factors (eg, the clinical environment). Recommendations and frameworks have been created to aid in the development of implementable guidance.
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