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Introduction: Trauma clinical guidance (guidelines, protocols, algorithms, etc) has been shown to improve patient outcomes; however, it is only used in about half of the patients to whom it applies. Guidance implementation is affected by intrinsic factors (eg, guidance format) as well as extrinsic factors (eg, the clinical environment). Recommendations and frameworks have been created to aid in the development of implementable guidance. We hypothesize that existing trauma clinical guidance lacks elements important for implementation.
Methods: The Framework for Guideline Implementability by Gagliardi, which consists of 22 elements arranged into eight domains, was used to evaluate trauma clinical guidance. A sample of 20 pieces of guidance, crafted by 11 professional organizations, were reviewed. Data were extracted to identify the presence or absence of each implementability element.
Results: All guidance provided a clear objective and 85% allowed for individualized application of recommendations based on clinical scenario. Approximately half of the guidance included formatting elements, such as graphic aids, to enhance usability, and 50% incorporated formal evidence grading. Patient-friendly tools accompanied 10% of guidance, and few discussed implementation strategies (25%) or quality metrics (30%) to evaluate guidance implementation.
Discussion: Clinical guidance exists on a spectrum, from narrative (eg, written documents) to executable tools (eg, automated decision support based on patient context). While integration of computable guidance into clinical workflows may be the ultimate goal in high-resource settings, there are other more feasible and even cost-free modifications developers may integrate into new guidance to improve implementation across settings.
Conclusion: Utilization of trauma clinical guidance is crucial for improving healthcare quality. To achieve this, guidance developers might leverage the elements in the new TRAUMA (Transparency, Robust inclusivity, Adaptability, Usability, Measurability, Accessibility) framework that enhance implementability. Future research is needed to validate this theoretical new framework's impact on clinical implementation and patient outcomes.
Level Of Evidence: IV.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12414163 | PMC |
http://dx.doi.org/10.1136/tsaco-2024-001610 | DOI Listing |
JMIR Ment Health
September 2025
National Institute of Health and Care Research MindTech HealthTech Research Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Background: Cross-sector collaboration is increasingly recognized as essential for addressing complex health challenges, including those in mental health. Industry-academic partnerships play a vital role in advancing research and developing health solutions, yet differing priorities and perspectives can make collaboration complex.
Objective: This study aimed to identify key principles to support effective industry-academic partnerships, from the perspective of industry partners, and develop this into actionable guidance, which can be applied across sectors.
Adv Emerg Nurs J
September 2025
Author Affiliations: Emory University Hospital, Atlanta, Georgia (Drs Alvarez and Davis); and Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia (Dr Davis).
Acute abnormal uterine bleeding is a frequent reason for emergency department visits and, in severe cases, can become life-threatening. Tranexamic acid is a potential treatment option. However, its use in this setting remains under-researched.
View Article and Find Full Text PDFRev Bras Enferm
September 2025
Universidade do Estado do Amazonas. Manaus, Amazonas, Brazil.
Objectives: to develop a mobile application prototype using Artificial Intelligence (AI) to predict and support the diagnosis of pulmonary tuberculosis in children - TB Kids.
Methods: technological development research of the prototyping type, based on the Rational Unified Process model and its four stages: conception, elaboration, construction and transition. The development of the TB Kids prototype took place from November 2022 to July 2023.
PLoS One
September 2025
NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and Institute of Ophthalmology University College London, London, United Kingdom.
Objectives: To describe the research principles and cohort characteristics of the multi-disciplinary Project HERCULES, an innovative model of safe high-volume outpatient eye-care service for patients with stable chronic eye diseases. Results and analyses of the workstreams within Project HERCULES will be reported elsewhere. The rationale was to improve eye-care capacity in the National Health Service (NHS) in England through the creation of technician-delivered monitoring in a large retail-unit in a London shopping-centre, with remote asynchronous review of results by clinicians (named Eye-Testing and Review through Asynchronous Clinic (Eye-TRAC)).
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
September 2025
Department of Electrophysiology, Abbott Inc, Chicago, IL.
We report the first use of the EnSite X system for intraoperative electrophysiological mapping during a robotic hybrid ablation (ROK-AF procedure) for long-standing persistent atrial fibrillation. Epicardial ablation targets were identified, and post-ablation electrical silencing was validated. Unlike conventional systems, its orientation-independent omnipolar technology provides directional activation vectors, high-resolution electrograms, and peak frequency analysis, thereby enhancing substrate characterisation.
View Article and Find Full Text PDF