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Endophytes are beneficial microorganisms that reside within plant tissues, playing a vital role in plant growth and stress tolerance. Endophytes successfully colonize host plants by employing a range of mechanisms, including cell wall modification, modulation of phytohormones, secretion of effector proteins, and the production of antioxidants. Certain endophytes can efficiently break down specific pollutants such as pesticides in the rhizosphere, phyllosphere, and endosphere. These microbes metabolize pesticides or alter their chemical structures using several enzymatic, genetic, or metabolic pathways. This review examines the underlying colonization mechanism of endophytes in plants, as well as their significance in pesticide degradation. The available data will raise many new questions about endophytic colonization dynamics, regulation of different genes involved in establishing endophytic associations and their role in pesticide degradation with a sustainable research perspective.
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http://dx.doi.org/10.1021/acs.jafc.5c06182 | DOI Listing |
PLoS Biol
September 2025
Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America.
Inter-laboratory replicability is crucial yet challenging in microbiome research. Leveraging microbiomes to promote soil health and plant growth requires understanding underlying molecular mechanisms using reproducible experimental systems. In a global collaborative effort involving five laboratories, we aimed to help advance reproducibility in microbiome studies by testing our ability to replicate synthetic community assembly experiments.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
September 2025
Arencibia Clinic, San Sebastian, Spain.
Follicular unit extraction (FUE) has become a leading technique in hair transplantation, yet optimal management of the donor area remains a clinical challenge. This systematic review analyzes intraoperative and postoperative interventions applied to the donor area in FUE hair transplantation, with a focus on both clinical outcomes and the cellular and molecular mechanisms involved in tissue repair, inflammatory response, and regenerative processes. A comprehensive literature search was conducted in PubMed and EMBASE (January 2000-June 2025), identifying clinical studies that evaluated donor area treatments and reported outcomes related to healing, inflammation, infection, and patient satisfaction.
View Article and Find Full Text PDFFront Plant Sci
August 2025
Plant Protection and Biomolecular Diagnosis Department, Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications, Alexandria, Egypt.
The utilization of arbuscular mycorrhizal fungi (AMF) and spp. correlates with improved plant nutrition and the stimulation of systemic plant defenses in response to pathogen challenges. Nonetheless, studies examining the effects of AMF colonization and the foliar application of the isolate Tvd44 on viral infection are limited.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
Laboratory of Jessica Galloway-Peña, Texas A&M University, Department of Veterinary Pathobiology, Interdisciplinary Graduate Program in Genetics and Genomics, College Station, TX, United States.
Introduction: Acute myeloid leukemia (AML) patients are highly susceptible to infection. Moreover, prophylactic and empirical antibiotic treatment during chemotherapy disrupts the gut microbiome, raising the risk for antibiotic-resistant (AR) opportunistic pathogens. There is limited data on risk factors for AR infections or colonization events in treated cancer patients, and no predictive models exist.
View Article and Find Full Text PDFFront Oral Health
August 2025
School of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Balance of the oral-intestinal axis microbiota is essential for maintaining oral mucosal health. The occurrence of oral disease is closely linked to the microbiota, this disorder is closely related to the pathogenesis of oral mucosal diseases, such as oral lichen planus, recurrent aphthous ulcer, oral candidiasis and squamous-cell carcinoma. As a microorganism that is beneficial to host health, probiotics can show multi-dimensional therapeutic effects in oral mucosal diseases by targeting and regulating the immune microenvironment of the oral mucosa, inhibiting the colonization of pathogenic bacteria and repairing the barrier function.
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