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Article Abstract
We herein report a catalyst- and thiol-free method for synthesizing thioesters from arenes, carboxylic acids, and tetramethylthiourea in a one-pot process, by combining arene activation the interrupted Pummerer reaction with an electron donor-acceptor complex strategy. The method enables late-stage modification of complex bioactive molecules, and operates effectively under natural sunlight, highlighting its potential synthetic value.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366446 | PMC |
| http://dx.doi.org/10.1039/d5sc05002b | DOI Listing |
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