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Objectives: To compare the effects of conventional therapy and press needle combined therapy on idiopathic sudden sensorineural hearing loss.
Methods: The retrospective case-control study was conducted from December 2023 to January 2024 at Department of Otorhinolaryngology, Changzhou Third People's Hospital, China, and comprised patients with idiopathic sudden sensorineural hearing loss ISSNHL admitted from September 2021 to November 2023. The patients were divided into control group CON in which conventional therapy was used, and the PN group in which the press needle therapy was given additionally. The groups were compared with respect to clinical effects. Data was analysed using SPSS 20.
Results: Of the 297 patents, 143(48%) were in group CON and 154(52%) were in group PN. There was no difference between the groups in terms of age and gender (p>0.05). The PN group showed greater changes in pure-tone audiometric thresholds than the CON group (p<0.05), and the difference was more significant in high-frequency hearing loss patients (p<0.05).
Conclusions: The addition of press needle therapy showed better therapeutic recovery in idiopathic sudden sensorineural hearing loss patients compared to the conventional therapy alone.
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http://dx.doi.org/10.47391/JPMA.20232 | DOI Listing |
J Drugs Dermatol
September 2025
Background: Alopecia universalis (AU) is the most severe form of alopecia areata (AA), characterized by complete scalp and body hair loss. While post-COVID-19 hair loss is often attributed to telogen effluvium (TE), emerging evidence suggests that COVID-19 may also trigger AU through immune dysregulation, particularly via interferon-gamma (IFN-γ)-mediated inflammation. The chronic and relapsing nature of AU raises challenges in long-term disease management, particularly regarding treatment duration and relapse prevention.
View Article and Find Full Text PDFJACC Clin Electrophysiol
September 2025
Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milano, Italy; Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy. Electronic address:
Calmodulinopathies are very rare genetic disorders associated with a high risk for sudden cardiac death. Disease-causing variants in 1 of the 3 identical CALM genes cause severe forms of long QT syndrome, catecholaminergic polymorphic ventricular tachycardia, or idiopathic ventricular fibrillation, and there are many unanswered questions concerning management and underlying mechanisms. What is currently known depends largely on the initial publications from the ICamR (International Calmodulinopathy Registry).
View Article and Find Full Text PDFCureus
July 2025
Otolaryngology - Head and Neck Surgery, University General Hospital of Patras, Patras, GRC.
Background And Objective: Idiopathic sudden sensorineural hearing loss (ISSNHL), which is an otologic emergency characterized by rapid-onset inner-ear hearing loss without an identifiable cause, remains a clinically urgent but poorly understood entity. While environmental factors have been proposed as potential triggers, prior studies show conflicting results. This study aimed to examine associations between weekly ISSNHL incidence and meteorological variables, including temperature, wind speed, and atmospheric pressure, in a Mediterranean city over a six-year period.
View Article and Find Full Text PDFJ Pers Med
August 2025
ENT Department, Fondazione Policlinico Universitario Agostino Gemelli-IRCCS, 00168 Rome, Italy.
Sudden sensorineural hearing loss (SSNHL) represents a challenging clinical entity with variable prognosis. Audiometric curve configuration has been proposed as a predictor of recovery. This study aimed to evaluate the association between audiogram morphology at onset and hearing outcome in patients with idiopathic unilateral SSNHL treated with standardized therapy.
View Article and Find Full Text PDFEar Hear
August 2025
School of Computer and Communication Engineering, Beijing Advanced Innovation Center for Materials Genome Engineering, University of Science and Technology Beijing, Beijing, China.
Objectives: The prognosis of idiopathic sudden sensorineural hearing loss (ISSNHL) is heterogeneous. The study aimed to investigate the prognostic factors of ISSNHL and develop machine-learning models with multiple imputation to predict the prognosis of ISSNHL.
Design: A retrospective study was undertaken on a cohort of 600 patients with ISSNHL who underwent standardized treatment protocols.