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This study describes lower limb musculotendon unit (MTU) forces and powers during sprint cycling. Seven participants (2 female) performed maximal effort cycling at optimal cadence. Three-dimensional motion capture, pedal forces, and surface electromyography (EMG) data were input into participant-calibrated EMG-informed neuromusculoskeletal models to evaluate forces and powers produced by 18 lower-limb MTUs. In the pushing phase (10° - 170°, relative to the right crank at top dead centre), the hip adductor group generated the highest average force (1623.78 ± 980.62 N) and the vastus lateralis generated the highest average positive power (193.11 ± 153.07 W). In the pulling phase (170°-350°), the hip adductor group generated the highest average force (1140.48 ± 482.57 N) and average power (60.47 ± 68.87 W). In the transition phase (350°-10°), the vastus lateralis generated the highest average force (1432.26 ± 1169.40 N) and average power (76.98 ± 71.84 W). MTU power crank cycle-profiles were generated for each participant, highlighting differences in patterns of MTU power generation. Future work is needed to determine if targeted training based on cyclist-specific MTU force and power model outputs would lead to improved sprint cycling performance.
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http://dx.doi.org/10.1016/j.jbiomech.2025.112890 | DOI Listing |
Muscle Nerve
September 2025
Department of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, South Korea.
Introduction/aims: There is a lack of up-to-date information on the burden of motor neuron diseases (MNDs) in the United States (US). This study aimed to estimate trends in the prevalence, incidence, mortality, and disability-adjusted life years (DALYs) for MNDs in the US from 1990 to 2021.
Methods: We performed a secondary analysis of MNDs in the US using estimates of prevalence, incidence, and mortality obtained from analyses of the Global Burden of Disease 2021 dataset.
J Hosp Adm
January 2025
Department of Population Health, University of Cincinnati, Cincinnati, United States.
Objective: Occupational sharps and needlestick injuries (SNSI) are a significant and persistent challenge in the U.S. healthcare work environment.
View Article and Find Full Text PDFFront Rehabil Sci
August 2025
Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, CA, United States.
Introduction: Spinal cord injury (SCI) presents a significant burden to patients, families, and the healthcare system. The ability to accurately predict functional outcomes for SCI patients is essential for optimizing rehabilitation strategies, guiding patient and family decision making, and improving patient care.
Methods: We conducted a retrospective analysis of 589 SCI patients admitted to a single acute rehabilitation facility and used the dataset to train advanced machine learning algorithms to predict patients' rehabilitation outcomes.
Front Bioeng Biotechnol
August 2025
Department of Orthopaedics, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Objective: Due to its inherent high instability, the selection of fixation strategies for unilateral Denis type II sacral fractures remains a controversial challenge in the field of traumatic orthopedics. This study focuses on unilateral Denis type II sacral fractures. By applying three different fixation methods, it aims to explore their biomechanical properties and provide a theoretical basis for optimizing clinical fixation protocols.
View Article and Find Full Text PDFBackground: Anticonvulsants are widely used in treating patients with mental and neurological disorders. Their long-term use increases the risk of a decrease in bone mineral density (BMD) and low-energy fractures. Despite the growing number of studies of drug-induced osteoporosis, the effect of anticonvulsants on bone microarchitecture remains poorly studied.
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