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This study aimed to examine changes in heart rate variability (HRV) across three match-related time points (pre-match, during the match, and post-match) and to explore whether these physiological responses differed between winners and losers in competitive padel. Twelve matches were analyzed, involving 11 high-level Finnish padel players ranked within the national top 24. HRV was recorded before, during, and immediately after each match, with each measurement lasting a minimum of five min. Time-domain (e.g., SDNN, RMSSD, pNN50), frequency-domain (e.g., LF, HF), and non-linear (e.g., SD1, SD2) HRV metrics were extracted for analysis. All matches took place in Tampere, Finland, under controlled conditions. Results revealed significant intra-match fluctuations in HRV across all domains. Moreover, losing players exhibited consistently higher relative heart rate during the match, suggesting greater physiological strain. This study contributes novel evidence on the dynamic nature of autonomic responses in padel and supports the integration of HRV monitoring in performance and recovery management protocols for high-level athletes.
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http://dx.doi.org/10.3390/jfmk10030306 | DOI Listing |
Adv Med Sci
September 2025
Chair and Department of Medical Microbiology, Medical University of Lublin, Lublin, Poland. Electronic address:
Purpose: The aim of the study was to evaluate the toxicity of triclosan in the Danio rerio model and mammalian cells, as well as to assess its antimicrobial and antibiofilm activity against selected bacterial pathogens.
Methods: Triclosan toxicity was assessed in Danio rerio embryos in accordance with OECD Test Guideline 236: Fish Embryo Acute Toxicity (FET) Test. Cytotoxicity was evaluated in vitro using the MTT assay on human dermal fibroblasts (BJ) and rat cardiomyoblasts (H9c2).
Int J Cardiol
September 2025
Institute of Sports Medicine and Science, National Italian Olympic Committee, Largo Piero Gabrielli, 1, 00197 Rome, Italy.
Introduction: Endurance athletes are expected to present a cardiac remodeling characterized by eccentric hypertrophy. Differentiation from underlying cardiomyopathy mimicking a similar cardiac remodeling may be challenging. Myocardial work indexes (MWI) have been shown to be useful in distinguishing between physiological adaption and pathological changes in the athletes' heart.
View Article and Find Full Text PDFHeart Rhythm
September 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. Electronic address:
Background: The effectiveness of ethanol infusion of the vein of Marshall (EIVOM) for persistent atrial fibrillation (AF) in patients with mitral valve replacement (MVR) remains to be determined.
Objectives: This study investigated the effectiveness and safety of EIVOM in catheter ablation of persistent AF in patients with MVR.
Methods: This is a retrospective case-control study.
Nitric Oxide
September 2025
Department of Physics, Wake Forest University, Winston-Salem, NC 27109, USA; Translational Science Center, Wake Forest University, Winston-Salem, NC 27109, USA. Electronic address:
We recently demonstrated a rapid reaction between labile ferric heme and nitric oxide (NO) in the presence of reduced glutathione (GSH) or other small thiols in a process called thiol-catalyzed reductive nitrosylation, yielding a novel signaling molecule, labile nitrosyl ferrous heme (NO-ferroheme), which we and others have shown can regulate vasodilation and platelet homeostasis. Red blood cells (RBCs) contain high concentrations of GSH, and NO can be generated in the RBC via nitrite reduction and/or RBC endothelial nitric oxide synthase (eNOS) so that NO-ferroheme could, in principle, be formed in the RBC. NO-ferroheme may also form in other cells and compartments, including in plasma, where another small and reactive thiol species, hydrogen sulfide (HS/HS), is also present and may catalyze NO-ferroheme formation akin to GSH.
View Article and Find Full Text PDFBehav Brain Res
September 2025
Department of Pharmacology of the School of Medicine of Ribeirao Preto, University of Sao Paulo, 14049-900, Ribeirao Preto, SP, Brazil. Electronic address:
Aims: Acute restraint stress (RS) has been reported to activate the supraoptic nucleus of the hypothalamus (SON). The aim of the present study was to evaluate the role of glutamatergic neurotransmission in the SON on autonomic [mean arterial pressure (MAP), heart rate (HR), and tail cutaneous temperature], neuroendocrine (plasma levels of corticosterone, oxytocin, and vasopressin), and behavioral responses to RS.
Methods: Male Wistar rats with bilateral SON cannulas received microinjections of NMDA or non-NMDA receptor antagonists or vehicle before restraint stress, and the effects on cardiovascular, tail temperature, hormonal, and behavioral responses were evaluated RESULTS: Microinjection of DL-AP7 or NBQX into the SON reduced MAP increases and tail temperature decreases induced by RS.