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In order to precisely obtain the magnitude and orientation of in-situ stress in coal mine roadway, the principle and calculation method of hydraulic fracturing technique for in-situ stress with two arbitrary holes were established in this study. Deriving from the basic principle of the traditional hydraulic fracturing in-situ stress testing, this method, based on the basic data of in-situ stress measured from two arbitrary test holes, performed three stress equivalent transformations following the stress transformation formula in elasticity mechanics. The results suggest that all six stress values representing the stress state at a point were accurately obtained after mechanical and mathematical derivation. Furthermore, the practical application and in-situ stress calculation process of this method were introduced with the Nazuo Coal Mine in Fuyuan County, Yunnan Province of China as the engineering foundation, verifying that the testing results were relatively accurate. The proposed method has addressed the limitations of the traditional single-hole hydraulic fracturing method and mitigated the drawbacks of the three-hole hydraulic fracturing method, what is high requirements for drilling quality and is not practical. So it can be treated as a simple, accurate method for hydraulic fracturing in-situ stress testing.
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http://dx.doi.org/10.1038/s41598-025-16099-x | DOI Listing |
J Refract Surg
September 2025
From National Engineering Research Center of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Purpose: To use parametric numerical simulation to characterize and compare the differences in corneal biomechanical responses to laser in situ keratomileusis (LASIK) and keratorefractive lenticule extraction (KLEx) under various surgical settings.
Methods: The Finite Element Model was used in a parametric study to evaluate corneal biomechanical responses to LASIK and KLEx, considering variations in preoperative corneal thickness, corneal flap/cap thickness and diameter, refractive correction, and optical zone diameter. Surgery-induced stress, displacement, and interface contact pressure were compared between LASIK and KLEx using the Wilcoxon signed-rank test.
Small Methods
September 2025
Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong) and School of Life Science, Shanghai University, Nantong, 226011, China.
Timely blood resupply is a clinical strategy to treat myocardial infarction, which unavoidably causes myocardial ischemia-reperfusion injury. With disturbed electrical conduction and oxidative stress in infarcted myocardium, injured heart experiences a negative ventricle remodeling process, and finally leads to heart failure. Nitric oxide (NO) is a short-lived signaling molecule regulating cardiovascular homeostasis, while vasodilation of systemic vasculature is accompanied by its exogenous supplementation.
View Article and Find Full Text PDFLangmuir
September 2025
Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati, Kamrup, Assam 781039, India.
The efficient and sustainable remediation of contaminated water calls for catalytic systems that must clean broadly, endure widely, and last repeatedly. In this regard, we report the development of sulfonate-functionalized core-shell hydrogel beads embedded with synthesized gold nanoparticles (AuNPs) that exhibit intrinsic oxidase-like activity without requiring external light or chemical oxidants. The sulfonate ligands modulate the surface electronic environment of the AuNPs, facilitating singlet oxygen generation via a nonplasmonic, radiationless mechanism.
View Article and Find Full Text PDFAdv Mater
September 2025
Key Laboratory of In-Fiber Integrated Optics of Ministry of Education, College of Physics and Optoelectronic Engineering, Harbin Engineering University, Harbin, 150001, China.
Recently, joint replacement surgery is facing significant challenges of patient dissatisfaction and the need for revision procedures. In-situ monitoring of stress stability at the site of artificial joint replacement during postoperative evaluation is important. Mechanoluminescence (ML), a novel "force to light" conversion technology, may be used to monitor such bio-stress within tissues.
View Article and Find Full Text PDFNanotechnology
September 2025
State Key Laboratory of Optoelectronic Materials and Technologies School of Chemistry and Chemical Engineering, Sun Yat-Sen University, No 135, XinGangXi Road, Guangzhou 510275, guangzhou, 510275, CHINA.
Silicon carbide nanowires (SiC NWs) combine the benefits of bulk SiC materials with the properties of low-dimensional nanomaterials. They are known for their excellent mechanical strength and durability, which are critical for their potential applications in high-stress environments and micro-nano functional systems. Here, the mechanical properties and deformation mechanisms of 2H-SiC NWs with rare defects in the [0001] orientation are reported.
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