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During a hurricane, it is vital that individuals receive communications that are easy to process and provide sufficient information to allow informed hurricane preparedness decisions and prevent loss of life. We study how different hurricane warning scales, the traditional Saffir-Simpson Hurricane Wind Scale (SSHWS) versus the newly developed Tropical Cyclone Severity Scale (TCSS), impact intent to evacuate and understanding of hurricane severity. We use a between-subject design where participants are assigned to either the traditional SSHWS or the new TCSS scale. We collected data in a large-scale (~ 4000 participants) online experiment to examine potential differences in comprehension, risk perception, anticipated evacuation, and preparation decisions among residents in U.S. coastal states prone to hurricanes. We find that participants using the TCSS scale are better at identifying the main hazard of a hurricane. For evacuation, the TCSS leads to significantly higher evacuation intent as opposed to SSHWS in cases where the TCSS is at least two categories higher (due to rainfall or storm surge being the main hazard rather than wind). In addition, the TCSS also seems to have a positive effect on taking appropriate precautionary measures, though not always at our stated significance level. Overall, our results demonstrate that people make better informed and more appropriate decisions with the TCSS as opposed to the currently used SSHWS. Protocol Registration The stage 1 protocol for this Registered Report was accepted in principle on 14 October 2024. The protocol, as accepted by the journal, can be found at: https://doi.org/10.17605/OSF.IO/AYXTK . The approved Stage 1 protocol is available here: https://osf.io/m3swr .
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http://dx.doi.org/10.1038/s41598-025-14170-1 | DOI Listing |
J Biotechnol
August 2025
School of Food and Health, Beijing Technology and Business University, Beijing 100048, China; Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University (BTBU), Beijing 100048, China. Electronic address:
Granaticins, a class of bioactive benzoisochromanequinones (BIQs), are natural blue pigments with biological activities, including antibacterial properties and promising clinical anticancer applications. However, their clinical and industrial applications are limited by low production yields and unclear biosynthetic regulation. In this study, we identified a rare in-cluster two-component system (TCS; orf10/orf11) within the granaticin biosynthesis-related gene cluster (BGC) of Streptomyces vilmorinianum YP1, a novel high-yielding producer.
View Article and Find Full Text PDFSci Rep
August 2025
School of Geosciences, University of South Florida, Tampa, USA.
During a hurricane, it is vital that individuals receive communications that are easy to process and provide sufficient information to allow informed hurricane preparedness decisions and prevent loss of life. We study how different hurricane warning scales, the traditional Saffir-Simpson Hurricane Wind Scale (SSHWS) versus the newly developed Tropical Cyclone Severity Scale (TCSS), impact intent to evacuate and understanding of hurricane severity. We use a between-subject design where participants are assigned to either the traditional SSHWS or the new TCSS scale.
View Article and Find Full Text PDFJ Endocrinol Invest
July 2025
Department of Pain Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Purpose: Diabetic peripheral neuropathy (DPN) is one of the most common complications of type 2 diabetes mellitus (T2DM). In recent years, it has been reported that the progression of DPN is associated with altered gut microbiota and serum metabolites. However, the alterations of the gut microbiota and interaction with metabolites are not well understood in DPN patients.
View Article and Find Full Text PDFAm J Transl Res
January 2025
College of Acupuncture and Tuina, Changchun University of Chinese Medicine Changchun 130117, Jilin, China.
Objectives: Clinical studies suggest that Chinese Tuina therapy may benefit diabetic peripheral neuropathy (DPN), but the evidence is inconclusive. This study evaluates its clinical efficacy and safety for DPN treatment.
Methods: Ten databases were searched, covering the period from their inception to February 21, 2024.
J Diabetes
January 2025
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Objective: To determine whether the use of herbal medicines combined with conventional treatment is more effective than conventional medication alone in improving clinical symptoms in patients with diabetic distal symmetric polyneuropathy (DSPN).
Methods: This multicenter, placebo-controlled, double-blind, randomized controlled clinical trial recruited patients from 6 clinical centers in mainland China. A total of 188 patients were randomly assigned in a 1:1 ratio to the treatment group (Tangbi Formula plus methylcobalamin) and the control group (placebo plus methylcobalamin).