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In recent years, bidirectional convolutional recurrent neural networks (RNNs) have made significant breakthroughs in addressing a wide range of challenging problems related to time series and prediction applications. However, the performance of the models is highly dependent on the hyperparameters chosen. Hence, we propose an automatic method for hyperparameter optimization and apply a bidirectional convolutional RNN based on the improved swarm intelligence optimization (sparrow search) to solve regression prediction problems. Specifically, a parallel multiscale dilated convolution (PMDC) module was designed to capture both local and global spatial correlations. This method utilizes convolution with different dilation rates to expand the receptive field without increasing the complexity of the model. Meanwhile, it integrates parallel multiscale structures to extract features at different scales and enhance the model's understanding of the input data. Then, the bidirectional gated recurrent units (BGRUs) learn temporal information from the convolutional features. To address the limitations of empirical hyperparameter selection, such as slow training and low efficiency, a novel PMDC-BGRU model integrated with a pretrained sparrow search algorithm (SSA) was proposed for hyperparameter optimization. Finally, experiments on multiple datasets verified the superiority of the algorithm and explained the flexibility of intelligent optimization algorithms in solving model parameter optimization.
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http://dx.doi.org/10.1109/TNNLS.2025.3596244 | DOI Listing |
Front Microbiol
August 2025
BIOASTER, Lyon, France.
We propose an innovative technology to classify the Mechanism of Action (MoA) of antimicrobials and predict their novelty, called HoloMoA. Our rapid, robust, affordable and versatile tool is based on the combination of time-lapse Digital Inline Holographic Microscopy (DIHM) and Deep Learning (DL). In combination with hologram reconstruction.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, 611731, PR China; Yangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou, Zhejiang, 313001, PR China; Laboratory for Microwave Spatial Inte
Background: X-ray fluorescence (XRF) technology is a promising method for estimating the metal element content in ores, which helps in understanding ore composition and optimizing mining and processing strategies. However, due to the presence of a large number of redundant features in XRF spectra, traditional quantitative analysis models struggle to effectively capture the nonlinear relationship between element concentration and spectral information of XRF, making it more difficult to accurately predict metal element concentrations. Thus, analyzing ore element concentrations by XRF remains a significant challenge.
View Article and Find Full Text PDFJ Chem Inf Model
September 2025
Key Laboratory of Micro-nano Sensing and IoT of Wenzhou, Wenzhou Institute of Hangzhou Dianzi University, Wenzhou 325038, China.
Transcription factors (TFs) are essential proteins that regulate gene expression by specifically binding to transcription factor binding sites (TFBSs) within DNA sequences. Their ability to precisely control the transcription process is crucial for understanding gene regulatory networks, uncovering disease mechanisms, and designing synthetic biology tools. Accurate TFBS prediction, therefore, holds significant importance in advancing these areas of research.
View Article and Find Full Text PDFBasic Clin Pharmacol Toxicol
October 2025
Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.
Early detection of diseases is a critical pillar in advancing modern healthcare, offering timely interventions and better patient outcomes. This overview highlights a range of machine learning (ML) approaches that are transforming early disease diagnosis. We discuss how traditional supervised and unsupervised methods, alongside advanced deep learning and reinforcement learning techniques, are utilized to detect early disease markers, often before clinical symptoms appear.
View Article and Find Full Text PDFPhysiol Meas
September 2025
College of Medicine and Biomedical Information Engineering, Northeastern University, Shenyang 110169, People's Republic of China.
The aortic pressure waveform (APW) is relevant to diagnosing and treating cardiovascular diseases. While various non-invasive methods for APW estimation exist, more accurate and practical monitoring methods are required. This study introduces a hybrid model combining variational mode decomposition improved by particle swarm optimization (PSO-VMD) and gated recurrent unit (GRU) networks (PSO-VMD-GRU) to reconstruct the APW from the brachial pressure waveform (BPW).
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