Factors Associated with Exertional Desaturation in Patients with Chronic Obstructive Pulmonary Disease.

Int J Chron Obstruct Pulmon Dis

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Yonsei University Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea.

Published: August 2025


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Article Abstract

The six minute walk test (6MWT) has a prognostic role in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to determine the factors associated with desaturation during the 6MWT in patients with COPD. This study utilized data from the prospective KOrea COPD Subgroup Study (KOCOSS) cohort. The results of the 6MWT performed at enrollment were analyzed in this study. A total of 1789 participants performed the 6MWT. Among them, 185 (10.3%) experienced desaturation during 6MWT. Old age, ex-smoker, low forced expiratory volume in one second (%), and high COPD assessment test score were significantly associated with exertional desaturation.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358123PMC
http://dx.doi.org/10.2147/COPD.S522341DOI Listing

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