Treatment choice and sexual health outcomes in gay and bisexual men with prostate cancer.

Background: The differential impacts of radical prostatectomy (RP) and external beam radiotherapy (EBRT) on sexual health in gay and bisexual men (GBM) with prostate cancer remain understudied, limiting recommendations incorporating preferred sexual behavior.

Methods: Secondary analysis of Restore-2 compared outcomes in GBM after RP (n = 127) or EBRT (n = 27).

Results: Compared to RP, EBRT was associated with lower rates of climacturia (11% vs.

Sexual Orientation and Gender Identity Measures for Cancer Research: Feedback from Older Americans.

To improve upon measures of sexual orientation and gender identity (SOGI) used in previous studies, we created and tested seven measures for inclusion in cancer research and refined them based on input from study participants. Between February and March 2024, cognitive interviews were conducted virtually with a purposive sample of 18 adults ≥50 years old. Equal numbers of participants identified as LGBTQ+ ( = 9) and cisgender heterosexual ( = 9).

Prevalence of loneliness states among the US adult population: Findings from the 2022 HINTS-6.

Introduction: In 2023 the U.S. Surgeon General declared loneliness and social isolation as significant public health issues, linked to adverse outcomes such as chronic disease, mental health disorders, and mortality.

Sexual function and dysfunction in the LGBTQIA+ community-including before and after gender-affirming surgery: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024).

Introduction: Evidence-based clinical practice guidelines focused on sexual (dys)function for the LGBTQIA+ (ie, lesbian, gay, bisexual, transgender, queer/questioning, intersex, and asexual) community, including before and after gender-affirming surgery, are still scarce.

Objectives: To provide an overview and recommendations for sexual (dys)function among individuals with diverse sexual orientations, transgender and gender-diverse individuals, and intersex individuals/individuals with differences of sexual development (DSD).

Methods: A committee of experts conducted a comprehensive review of the literature, focusing on scientific publications since the last consultation, for the fifth International Consultation on Sexual Medicine.

Cancer survivors' health outcomes over the life course: differences by sexual orientation and gender identity.

Purpose: This study seeks to examine sexual and gender minority (SGM) cancer survivors' quality of life (QoL) by age at diagnosis and time since diagnosis.

Methods: This secondary data analysis utilized 2014-2023 Behavior Risk Factor Surveillance Survey data. The survey respondents consisted of 1708 SGM cancer survivors and 56,184 heterosexual cisgender cancer survivors.

A Cross-Sectional Analysis of Psychosocial Mediators Between Discrimination and Health-Related Quality of Life Among Sexual and Gender Minority Cancer Survivors.

Background: Acts of discrimination detrimentally impact the quality of life of sexual and gender minority (SGM) cancer survivors. However, it is unclear how demographic and psychosocial factors shape the impact of discrimination on health.

Aims: To evaluate the intermediating role of everyday discrimination on physical and mental health-related quality of life (HRQOL), and how such relationships vary based on the demographic and psychosocial factors of SGM survivors.

Participants' reactions to the inclusion of Sexual Orientation and Gender Identity (SOGI) measures in an established large-scale cohort: The California Teachers Study.

Sexual and gender minority (SGM) populations are more likely than non-SGM populations to experience poor health outcomes but are underrepresented in research. The California Teachers Study (CTS) is a large prospective observational cohort that, in its 2017-2019 survey, included sexual orientation and gender identity (SOGI) measures and also asked participants to provide feedback on the questionnaire. We conducted an inductive content analysis of participants' feedback responses and used these qualitative codes to a) identify which participants commented on SOGI and b) establish whether these participants had a positive, negative, or ambiguous reaction to the measures.

Minority Stress Clusters and Health and Cancer Care Outcomes of Sexual and Gender Minority Cancer Survivors.

Structural factors affect the health of sexual and gender minority (SGM) cancer survivors, yet how people experience minority stress within their social and health care systems remains unclear. We explored experiences of minority stress across health care and sociocultural contexts and their impact on health and cancer outcomes. We conducted a K-medoid cluster analysis (grouping technique) using data from 2519 participants (training subset = 2015, testing subset = 504) from OUT: The National Cancer Survey (2020-2021).

Implementation of mid-adult HPV vaccination guidelines into clinical practice.

Background: This study investigates the implementation of the 2019 U.S. guideline recommending shared clinical decision-making (SCDM) for HPV vaccination among mid-adults (ages 27-45) by health care providers.

Loneliness among adult cancer survivors in the United States: prevalence and correlates.

Loneliness is recognized as a significant public health concern, affecting quality of life and health outcomes, including cancer-related outcomes. Thus, it is essential to understand the prevalence and risk factors for loneliness in people with cancer. Through an exploratory analysis of secondary data from the Health Information National Trends Survey, we investigated the prevalence and correlates of loneliness among adult cancer survivors (N = 1,234).

Examining tobacco use at the intersection of gender, sexual orientation, race, and ethnicity using national U.S. data of sexual and gender diverse youth.

Objectives: To expand the literature documenting that tobacco use inequities persist and continue to increase for minoritized youth populations by exploring patterns of tobacco use across multiple intersections of sexual, gender, racial, and ethnic identities. Studies with this focus are needed to understand the degree to which tobacco use varies across groups who hold multiple minoritized identities.

Methods: The current study used a novel analytical approach- Exhaustive Chi-square Automatic Interaction Detection - to examine lifetime cigarette use among a U.

Testing an HPV Vaccine Decision Aid for 27- to 45-Year-Old Adults in the United States: A Randomized Trial.

Background: In the United States, human papillomavirus (HPV) vaccination among 27- to 45-y-olds (mid-adults) is recommended based on shared clinical decision making with a health care provider. We developed a patient decision aid tool to support the implementation of this mid-adult HPV vaccination guideline. The purpose of this study was to evaluate the effect of a patient decision aid tool for HPV vaccination, HPV DECIDE, compared with an information fact sheet among mid-adults who have not received the HPV vaccine.

Clinician Perspectives on Implementing HPV Vaccination Guidelines into Practice.

In the United States, HPV vaccination is available for unvaccinated 27 to 45 year olds based on a shared clinical decision with a health care provider. Since the implementation of the guideline, little has been known about provider perceptions of this recommendation. The purpose of this study was to elucidate health care provider perspectives on HPV vaccination for 27 to 45 year olds in the United States.

Development and evaluation of a decision aid for HPV vaccination among adults aged 27-45 years old in the United States.

Objective: To design, develop, and field test the HPV Decide decision tool to facilitate shared clinical decision-making recommendation for mid-adult HPV vaccination.

Methods: The 'HPV Decide' online tool was developed through a 6-step process, involving community and provider advisory boards, usability testing with 10 end users (unvaccinated adults aged 27-45), field testing interviews with another 10, and interviews with 18 healthcare providers. The process incorporated both inductive and deductive qualitative data analyses.

Discrimination against Gay and Bisexual Patients in Prostate Cancer Treatment: Results from the Study.

The purpose of this study was to examine the experiences of discrimination during prostate cancer treatment and assess the association with health-related quality of life (HRQOL) in a cohort of gay and bisexual men (GBM) prostate cancer survivors. This is a cross-sectional analysis of the 24-month follow-up survey from the clinical trial that tested the effectiveness of an online rehabilitation program tailored for GBM prostate cancer survivors in the U.S.

Needs and Opportunities for Anal Cancer Prevention in Patients Engaged With PrEP Care: Development of Conceptual Model.

Introduction: Populations at risk for HIV infection-including gay, bisexual, and other men who have sex with men (GBM) and transgender/gender diverse people (TGD)-are at disproportionate risk for anal cancer. Most anal cancers are caused by human papillomavirus (HPV) and are preventable with HPV vaccination and screening. Engaging at-risk populations who are already receiving HIV preventive care (eg, pre-exposure prophylaxis [PrEP]) may be an effective implementation strategy.

Utilization of Anal Cytology Screening among Sexual and Gender Minority Populations in Pennsylvania.

Background: Despite the risk of anal cancer in sexual and gender minority (SGM) populations, anal cancer screening remains infrequent and inconsistent in these populations. The objective of this analysis was to identify factors associated with anal cancer screenings among SGM populations using the Andersen's behavioral model of health services use.

Methods: Secondary analyses of two cross-sectional surveys from the 2020 (N = 1,125) and 2022 (N = 630) Pennsylvania LGBTQ Health Needs Assessment.

Does sexual rehabilitation work for gay and bisexual prostate cancer patients? Acceptability, feasibility, and efficacy results from the Restore-2 randomized controlled trial.

Purpose: Sexual minority prostate cancer patients have worse health-related quality of life outcomes than heterosexual patients. We conducted the first study to test whether sexual and urinary rehabilitation tailored for sexual minority patients was acceptable, feasible, and efficacious at improving their sexual and urinary function.

Methods: Restore-2 was a 24-month randomized controlled trial of an online biopsychobehavioral rehabilitation study for sexual minority men treated for prostate cancer experiencing sexual and/or urinary problems.

The Association of Stigma, School, and Family Factors with Patterns of Substance Use Among LGBTQ Youth.

Polysubstance use is associated with myriad short- and long-term health outcomes. Although prior research has documented differences in polysubstance use between lesbian, gay, bisexual, transgender, queer/questioning, and other sexual and gender minoritized (LGBTQ +) youth and their heterosexual/cisgender counterparts, as well as between subgroups of LGBTQ + youth, it is unknown how personal, family, and school factors are associated with substance use patterns among LGBTQ + youth. Using a large, national sample of 9646 LGBTQ + youth ages 13-17, we used latent class analysis to examine patterns of alcohol, tobacco, and marijuana use and to determine whether personal, family, and school factors predict class membership.

Advancing Equity in Cancer Care: The Critical Role of Sexual Orientation and Gender Identity Data Collection.

New study highlights critical gaps and opportunities to enhance equitable cancer care for sexual and gender minority patients.