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http://dx.doi.org/10.1164/rccm.202411-2184IM | DOI Listing |
Comput Methods Programs Biomed
September 2025
Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, 210096, China; Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing, Southeast University, Nanjing, 210096, China. Electronic address: xuji@s
Background: Photon counting computed tomography (PCCT) has emerged as a potential technology that is revolutionizing clinical CT imaging. Using photon counting detectors (PCDs), the PCCT counts each X-ray event and measures the corresponding energy above the noise floor with significantly higher spatial resolution. However, the multiple-energy-bin setting and much smaller pixels increase the raw data size of PCCT by 20-100 times compared to traditional CT.
View Article and Find Full Text PDFAJR Am J Roentgenol
September 2025
Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Patients with inflammation-associated coronary artery disease (CAD) may exhibit rapid progression and require regular coronary imaging. To evaluate the diagnostic performance of spectral photon-counting detector (PCD) coronary CTA with reduced radiation and contrast media doses for detecting coronary stenosis and in-stent restenosis in patients with inflammation-associated CAD. This prospective study enrolled patients with inflammation-associated CAD from January 2023 to March 2024.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
September 2025
From the Department of Otorhinolaryngology Head and Neck Surgery (J.G., Y.L., S.G.) and Department of Radiology (N.X., R.T., H.D.,Z.Y., Z.W., P.Z.), Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Background And Purpose: Isolated congenital middle ear malformation contributes significantly to congenital hearing loss and growth problems. This study aims to compare 0.1 mm isotropic ultra-high-resolution computed tomography and conventional high-resolution computed tomography for assessing isolated congenital middle ear malformation, using surgical exploration as the gold standard.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Institute of Materials Science, Vietnam Academy of Science and Technology, Hanoi, 10000, Viet Nam. Electronic address:
Background: Recent advancements in cancer therapeutics have catalyzed the development of noninvasive treatment modalities, including the utilization of fluorescent chemotherapeutic agents. These agents offer dual functionality, enabling targeted drug delivery, real-time tumor imaging, and personalized therapy monitoring. Such capabilities are instrumental in the progression toward more precise and effective cancer interventions.
View Article and Find Full Text PDFPhotochem Photobiol
September 2025
Department of Chemistry, Case Western Reserve University, Cleveland, Ohio, USA.
The development of biocompatible organic photosensitizers remains an important challenge for advancing image-guided photodynamic therapy. Specifically, photosensitizers that combine strong photodynamic activity, fluorescence emission for bioimaging, decrease or stop the proliferation of cancer cells, and allow synthetic accessibility are in high demand. Herein, we report the synthesis and characterization of a new class of alloxazine-based photosensitizers (ANOMe, A8OMe and A7OMe).
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