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Cancer is the leading cause of death among Hispanic/Latino individuals, yet many do not complete cancer screenings due to systemic barriers. To address this issue, Rochester Healthy Community Partnership (RHCP) created "Stories for Change: La detección temprana puede salvar vidas" (S4C-cancer prevention). This digital storytelling intervention involved eight Hispanic/Latino cancer survivors or co-survivors who shared their experiences by creating 2-min videos. Their heartfelt stories aim to help patients make informed decisions about cancer screenings. RHCP piloted S4C-cancer prevention at three clinical sites to assess intervention acceptability and success (cancer screenings completed). A total of 51 participants who were overdue for cancer screenings were recruited (breast = 13; cervical = 12; colorectal women = 14; colorectal men = 12). After viewing the intervention, 100% intended to be screened in the future. Within 7 months, 45% of participants completed their recommended cancer screenings. Among those who were screened, 89% stated that their decision was "very much" influenced by S4C-cancer prevention. Participants who did not complete screening cited barriers such as time, lack of access to health education, and fear. Those who had previously screened for the targeted cancer were more likely to complete screening after viewing S4C-cancer prevention. Additionally, participants suggested enhancing the videos by including more education on various cancer topics. We found high acceptability of S4C-cancer prevention. Despite all participants intending to get screened, half completed screening within 7 months of viewing the intervention.
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http://dx.doi.org/10.1007/s13187-025-02696-x | DOI Listing |
Eur J Case Rep Intern Med
August 2025
Division of Gastroenterology, Department of Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA.
Unlabelled: Pancreatic signet ring cell carcinoma (PSRCC) is a rare and aggressive subtype of pancreatic cancer with a dismal prognosis. We present the case of a 50-year-old male who, within six weeks, developed a pancreatic mass with liver metastases. Endoscopic ultrasound-guided biopsy confirmed PSRCC.
View Article and Find Full Text PDFEur J Case Rep Intern Med
August 2025
Division of Internal Medicine, University Hospital of Basel, Basel, Switzerland.
Unlabelled: Encephalitis is a potentially life-threatening condition with infectious or autoimmune aetiologies. Autoimmune encephalitis includes paraneoplastic variants associated with specific onconeural antibodies such as anti-Hu, frequently linked to malignancies. Herpes simplex virus type 1 (HSV-1) is the leading infectious cause in adults.
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September 2025
Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Cancer is a multifaceted disease driven by a complex interplay of genetic predisposition, environmental factors and lifestyle habits. With the accelerating pace of cancer research, the gut microbiome has emerged as a critical modulator of human health and immunity. Disruption in the gut microbial populations and diversity, known as dysbiosis, has been linked with the development of chronic inflammation, oncogenesis, angiogenesis and metastasis.
View Article and Find Full Text PDFIndian J Nucl Med
August 2025
Department of Nuclear Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Lung cancer is the leading cause of cancer and cancer-related deaths, and India ranks the fourth highest country. Lung cancer is a highly aggressive malignancy with a tendency for rapid progression, making early detection and prompt treatment essential for improving patient outcomes. Lung cancer can spread locally into surrounding tissue as well as travel through lymphatics to other parts of the body, most often to bone, brain, liver, and adrenal glands.
View Article and Find Full Text PDFJTO Clin Res Rep
October 2025
Clinical Research Center (CRC), Medical Pathology Center (MPC), Cancer Early Detection and Treatment Center (CEDTC), and Translational Medicine Research Center (TMRC), Chongqing University Three Gorges Hospital, Wanzhou District, Chongqing, People's Republic of China.
NUT carcinoma is a rare and highly aggressive malignancy characterized by rapid progression, resistance to conventional therapies, and an extremely poor prognosis. This report presents a 36-year-old patient with stage IIIB primary pulmonary NUT carcinoma who achieved remarkable clinical outcomes with NHWD-870 monotherapy, a novel BET inhibitor. After just 1 month of treatment, imaging revealed a partial response, and a complete response was achieved within 5 months.
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